Glenis Kathleen Scadding,Peter Kenneth Smith,Michael Blaiss et al.
Glenis Kathleen Scadding et al.
Allergic rhinitis in childhood has been often missed, mistreated and misunderstood. It has significant comorbidities, adverse effects upon quality of life and educational performance and can progress to asthma or worsen control of existing ...
Transcription Factors in the Development and Pro-Allergic Function of Mast Cells [0.03%]
转录因子在肥大细胞发育及促过敏功能中的作用
Mansi Srivastava,Mark H Kaplan
Mansi Srivastava
Mast cells (MCs) are innate immune cells of hematopoietic origin localized in the mucosal tissues of the body and are broadly implicated in the pathogenesis of allergic inflammation. Transcription factors have a pivotal role in the developm...
Omalizumab Reduces Unplanned Healthcare Interactions in Irish Patients With Chronic Spontaneous Urticaria [0.03%]
奥马珠单抗可减少爱尔兰慢性自发性荨麻疹患者的非计划就医次数
Katie Ridge,Vyanka Redenbaugh,Niall Conlon
Katie Ridge
Chronic spontaneous urticaria (CSU) is a common, debilitating skin disorder associated with impaired quality of life and psychological comorbidity. Symptoms can be difficult to control and many individuals will not respond to first line tre...
Hiroki Masumi,Yutaka Takemura,Tomoyuki Arima et al.
Hiroki Masumi et al.
Background: Oral food challenge (OFC) is the most reliable method for diagnosing food allergies. However, the scarcity of long-term data on eating habits of people after a negative OFC poses a challenge for provisional medical care. Objecti...
Neutrophilic Asthma Is Associated With Smoking, High Numbers of IRF5+, and Low Numbers of IL10+ Macrophages [0.03%]
中性粒细胞型哮喘与吸烟、IRF5+巨噬细胞数量高和IL10+巨噬细胞数量低有关
Nil Turan,T Anienke van der Veen,Christina Draijer et al.
Nil Turan et al.
Asthma is a heterogenous disease with different inflammatory subgroups that differ in disease severity. This disease variation is hampering treatment and development of new treatment strategies. Macrophages may contribute to asthma phenotyp...
Personalized Pollen Monitoring and Symptom Scores: A Feasibility Study in Grass Pollen Allergic Patients [0.03%]
基于草花粉过敏患者的个性化花粉监测及症状评分的可行性研究
Letty A de Weger,Peter Th W van Hal,Bernadette Bos et al.
Letty A de Weger et al.
Background: Pollen is a major trigger for allergic symptoms in sensitized individuals. Airborne pollen is usually monitored by Hirst type pollen samplers located at rooftop level, providing a general overview of the pollen distribution in t...
Allergic Rhinitis: What Do We Know About Allergen-Specific Immunotherapy? [0.03%]
过敏性鼻炎：我们对特异性免疫疗法了解多少？
Tadech Boonpiyathad,Mongkol Lao-Araya,Chirawat Chiewchalermsri et al.
Tadech Boonpiyathad et al.
Allergic rhinitis (AR) is an IgE-mediated disease that is characterized by Th2 joint inflammation. Allergen-specific immunotherapy (AIT) is indicated for AR when symptoms remain uncontrolled despite medication and allergen avoidance. AIT is...
Allergological Importance of Invertebrate Glutathione Transferases in Tropical Environments [0.03%]
热带环境中无脊椎动物谷胱甘肽S-转移酶的过敏重要性
Josefina Zakzuk,Ana Lozano,Luis Caraballo
Josefina Zakzuk
Glutathione-S transferases (GSTs) are part of a ubiquitous family of dimeric proteins that participate in detoxification reactions. It has been demonstrated that various GSTs induce allergic reactions in humans: those originating from house...
Alvaro Teijeiro,R Maximiliano Gómez
Alvaro Teijeiro
Bronchiolitis is a virus-associated infection of the lower respiratory tract exhibiting signs and symptoms of airway obstruction. Respiratory Syncytial Virus (RSV) is responsible in most cases; however, different rhinoviruses have also been...
A Pilot Study to Evaluate the Dietary Intake of Adults Attending a Food Allergy Clinic, and Compare the Results Against the Final Diagnostic Outcome [0.03%]
一项针对就诊于食物过敏门诊的成人摄入饮食的研究及与最终诊断结果对比的研究试点工作
Isabel J Skypala,Cecile F Taylor,Anthony Pallister et al.
Isabel J Skypala et al.
Background: The impact of poor diet on growth and development in children with a food allergy is well-recognized and researched. Food allergy is an increasing problem in adults, as are food intolerances. Another issue is the rising number o...