The Allergen-Specific IgE Concentration Is Important for Optimal Histamine Release From Passively Sensitized Basophils [0.03%]
特异性IgE的浓度对被动致敏嗜碱细胞组胺释放的影响重要
Peter Stoffersen,Per S Skov,Lars K Poulsen et al.
Peter Stoffersen et al.
Background: The basophil histamine release (HR) assay can be used for allergy diagnosis in addition to the conventional measurement of allergen-specific IgE (sIgE). Passive sensitization of basophils increases the versati...
Sarah Iuliano,Laurence Senn,Laura Moi et al.
Sarah Iuliano et al.
Beta-lactam allergy is a common problem in everyday medical practice and is recognized as a major public health issue. Carrying this label frequently leads to the avoidance of all beta-lactam antibiotics, favoring the use of other less pref...
Disease Impact, Diagnostic Delay, and Unmet Medical Needs of Patients With Cholinergic Urticaria in German-Speaking Countries [0.03%]
德国说德语地区胆碱性荨麻疹患者的疾病影响、诊断延迟和未满足的医疗需求
Sabine Altrichter,Emilia Mellerowicz,Dorothea Terhorst-Molawi et al.
Sabine Altrichter et al.
Background: Cholinergic urticaria (CholU) is a common type of chronic inducible urticaria. Little is known about the burden of the disease and its unmet medical needs. ...
Sex Differences in Airway Remodeling and Inflammation: Clinical and Biological Factors [0.03%]
气道重构和炎症的性别差异：临床与生物学因素
Carolyn Damilola Ekpruke,Patricia Silveyra
Carolyn Damilola Ekpruke
Asthma is characterized by an increase in the contraction and inflammation of airway muscles, resulting in airflow obstruction. The prevalence of asthma is lower in females than in males until the start of puberty, and higher in adult women...
Benralizumab in Patients With Severe Eosinophilic Asthma With and Without Chronic Rhinosinusitis With Nasal Polyps: An ANANKE Study post-hoc Analysis [0.03%]
伴有和不伴慢性鼻窦炎伴鼻息肉的重度嗜酸细胞性哮喘患者的本拉鲁单抗疗效：ANANKE研究事后分析
Maria D&#x;Amato,Francesco Menzella,Elena Altieri et al.
Maria D&#x;Amato et al.
Background: Severe eosinophilic asthma (SEA) in the presence of chronic rhinosinusitis with nasal polyps (CRSwNP) indicates the presence of a more extensive eosinophilic inflammation. Post-hoc analyses from a pivotal clin...
Multicentric and Observational Study of Omalizumab for Chronic Spontaneous Urticaria in Real-Life in Colombia [0.03%]
omalizumab治疗哥伦比亚真实世界慢性自发性荨麻疹的多中心观察研究
Elizabeth García-Gómez,Edgardo Chapman,María Beatriz García-Paba et al.
Elizabeth García-Gómez et al.
Background: Although chronic urticaria (CU) is a common, cause of medical consulting both in general practitioners and allergist specialists worldwide, there is little information about its behavior and management in Lati...
Findings of in vitro Analyses of Basophil Functions May Help Us Better Understand Drug Desensitization [0.03%]
体外 basophil 功能分析的发现有助于我们更好地理解药物脱敏现象
Masao Yamaguchi,Akiko Komiya,Maho Suzukawa et al.
Masao Yamaguchi et al.
Drug hypersensitivity can be an important problem during pharmacological management of various diseases. Patients diagnosed as having a drug allergy usually need to avoid the offending drug, either temporarily or for life. Another way of ov...
Evaluation of Stool Short Chain Fatty Acids Profiles in the First Year of Life With Childhood Atopy-Related Outcomes [0.03%]
生命早期粪便短链脂肪酸谱特征与儿童特应性相关结局的关系研究
Hsin Yue Cheng,James Chun Yip Chan,Gaik Chin Yap et al.
Hsin Yue Cheng et al.
Introduction: Short chain fatty acids (SCFAs) are the main intestinal intermediate and end products of metabolism of dietary fibers/polyphenols by the gut microbiota. The aim of this study was to evaluate the biological i...
Diagnosing Pediatric Patients With Hereditary C1-Inhibitor Deficiency-Experience From the Hungarian Angioedema Center of Reference and Excellence [0.03%]
匈牙利参考和卓越血管性水肿中心遗传性C1抑制剂缺乏症儿科患者的诊断经验
Noémi Andrási,Zsuzsanna Balla,Beáta Visy et al.
Noémi Andrási et al.
Background: Hereditary Angioedema with C1-inhibitor deficiency (C1-INH-HAE) is a rare disease characterized by recurrent subcutaneous and/or submucosal edematous (HAE) episodes, which may occur at any age. The mean age of...
Low Levels Matter: Clinical Relevance of Low Pru p 3 sIgE in Patients With Peach Allergy [0.03%]
低水平的Pru p 3 sIgE也重要：低Pru p 3 sIgE水平在桃过敏患者中的临床意义
Sara Balsells-Vives,Clara San Bartolomé,Rocío Casas-Saucedo et al.
Sara Balsells-Vives et al.
Many clinical lab settings still use 0.35 KUA/L as the cut-off for serum specific-IgE (sIgE) immunoassays, while the detection limit is 0.1 KUA/L. The clinical relevance of -low-level sIgE (0.1-0.35 KUA/L) remains controversial. Pru p 3 sIg...