Patterns of Clinical Reactivity in a Danish Cohort of Tree Nut Allergic Children, Adolescents, and Young Adults [0.03%]
丹麦一个包含儿童、青少年和年轻人的树坚果过敏队列的临床反应模式
Nanna Juel-Berg,Lau Fabricius Larsen,Niels Küchen et al.
Nanna Juel-Berg et al.
Background: Tree nut allergy is associated with severe reactions and poly-sensitization to other nuts and peanuts often occurs. There are regional differences in sensitization profiles that result in differences in clinic...
Real-Life Experience With Subcutaneous Plasma-Derived C1-Inhibitor for Long-Term Prophylaxis in Patients With Hereditary Angioedema: A Case Series [0.03%]
遗传性血管水肿长期预防的现实经验：人血浆衍生C1酯酶抑制剂皮下注射治疗的病例系列研究报告
Andrea Zanichelli,Chiara Suffritti,Valentina Popescu Janu et al.
Andrea Zanichelli et al.
Hereditary angioedema due to C1-inhibitor deficiency (C1-INH-HAE) is characterized by swelling attacks that may be even life-threatening. To reduce the frequency of attacks, some patients need a long-term prophylaxis (LTP). In addition to t...
Fiorella Petrelli,Daiana Giannini,Silvia Bilia et al.
Fiorella Petrelli et al.
Urticarial vasculitis (UV) is a small-vessel leukocytoclastic vasculitis characterized by different clinical manifestations ranging from long-lasting urticarial lesions to severe and potentially life-threatening multi-organ involvement. Oma...
Luane Marques de Mello,Faradiba Sarquis Serpa,Joseane Chiabai et al.
Luane Marques de Mello et al.
Objective: To assess the profile of allergist/immunologist (A/I) physicians in Brazil, the workplace, the access to diagnostic and therapeutic procedures, and the impact of the COVID-19 pandemic on professional practice. ...
Differences in Linear Epitopes of Ara h 9 Recognition in Peanut Allergic and Tolerant, Peach Allergic Patients [0.03%]
花生过敏和桃子过敏患者与耐受患者对Ara h 9线性表位识别的差异性研究
L Sánchez-Ruano,C Fernández-Lozano,M Ferrer et al.
L Sánchez-Ruano et al.
Background: Peanut-allergic patients from the Mediterranean region are predominantly sensitized to the lipid transfer protein (LTP) Ara h 9, and the peach LTP Pru p 3 seems to be the primary sensitizer. However, LTP sensi...
Changes in food-related costs during the COVID-19 pandemic among families managing food allergy [0.03%]
新冠肺炎大流行期间食物过敏家庭食品相关费用的变化
Michael A Golding,Cathérine Lemoine-Courcelles,Elissa M Abrams et al.
Michael A Golding et al.
Background: The COVID-19 pandemic has affected the supply, cost, and demand for certain foods, but it is not clear how these changes have affected food-allergic households. ...
β-arrestin-1 and β-arrestin-2 Restrain MRGPRX2-Triggered Degranulation and ERK1/2 Activation in Human Skin Mast Cells [0.03%]
人皮肤肥大细胞中βarrestin-1和βarrestin-2限制MRGPRX2触发的脱颗粒和ERK1/2活化
Zhao Wang,Zhuoran Li,Gürkan Bal et al.
Zhao Wang et al.
As a novel receptor that efficiently elicits degranulation upon binding to one of its numerous ligands, MRGPRX2 has moved to the center of attention in mast cell (MC) research. Indeed, MRGPRX2 is believed to be a major component of pseudo-a...
Basophil Activation Test as a Biomarker for Taxanes Anaphylaxis [0.03%]
他克莫司过敏 basophil activation test 值的临床研究
Lucila De Campos,Pedro Giavina-Bianchi,Shree Acharya et al.
Lucila De Campos et al.
Introduction: Taxanes are widely used chemotherapy agents, and their administration, despite premedication, is associated with hypersensitivity reactions (HR) in up to 9% of patients, 1% of which are severe. The mechanism...
Measuring the Impact of Food Immunotherapy on Health-Related Quality of Life in Clinical Trials [0.03%]
测量食物免疫疗法对临床试验中与健康相关的生活质量的影响
Melanie Lloyd,Audrey Dunn Galvin,Mimi L K Tang
Melanie Lloyd
Food allergy is a common, and often lifelong, disorder with considerable negative impact on the quality of life of those affected and their families. While several promising immunotherapies for food allergy have either been approved or are ...
Searching for Genetic Biomarkers for Hereditary Angioedema Due to C1-Inhibitor Deficiency (C1-INH-HAE) [0.03%]
遗传性血管水肿(C1抑制剂缺乏引起的[C1-INH-HAE])的基因生物标志物筛查
Faidra Parsopoulou,Gedeon Loules,Maria Zamanakou et al.
Faidra Parsopoulou et al.
Existing evidence indicates that modifier genes could change the phenotypic outcome of the causal SERPING1 variant and thus explain the expression variability of hereditary angioedema due to C1-inhibitor deficiency (C1-INH-HAE). To further ...