Innovative diagnostic techniques and their clinical implications in food allergy: current clinical practice and future perspectives [0.03%]
食物过敏的创新诊断技术及其临床意义：现行临床实践和未来展望
Carlo Maria Rossi,Stefania Merli,Linda Borgonovo et al.
Carlo Maria Rossi et al.
Food allergy (FA) is an immune-mediated adverse reaction to food components (mainly proteins) and represents an increasing global health problem, affecting millions of individuals and imposing substantial clinical, psychosocial, and economi...
Real-world outcomes of personalized sublingual immunotherapy for environmental allergies delivered through a telemedicine platform: a retrospective longitudinal cohort study [0.03%]
基于远程医疗平台个性化给药的舌下免疫疗法治疗环境过敏的真实世界结局：一项回顾性纵向队列研究
Chet Tharpe,Joshua Davidson,Kayla Mardaga et al.
Chet Tharpe et al.
Background: Allergen immunotherapy (AIT) is a disease-modifying treatment for IgE-mediated respiratory allergy, but real-world use is limited by access and adherence. Telemedicine-enabled sublingual immunotherapy (SLIT) m...
Protective effects of sodium hyaluronate nasal spray on murine nasal mucosa via preservation of airway surface liquid and mucociliary clearance [0.03%]
透明质钠鼻喷雾剂通过保持气道表面液和黏液纤毛清除作用保护小鼠鼻粘膜的作用研究
Weizheng Zhao,Jinqi Lang,Yongtai Wang et al.
Weizheng Zhao et al.
Background: Saline nasal irrigation is widely used in the management of nasal diseases; however, its inability to replicate the physicochemical properties of airway surface liquid (ASL) may limit its long-term efficacy. W...
Cat exposure and asthma outcomes in a cohort of children with asthma and allergy [0.03%]
接触猫与儿童哮喘和过敏患者的哮喘结局关系的研究
Resthie R Putri,Cecilia Lundholm,Anna Hedman et al.
Resthie R Putri et al.
Introduction: The impact of current pet exposure on children with allergic asthma is not yet fully understood. This study aimed to investigate the association between cat exposure and asthma outcomes in children with esta...
The forgotten billion: bridging the global allergy care chasm through scalable, equity-driven strategies [0.03%]
被遗忘的百亿人口：通过可扩展和公平驱动的战略弥合全球过敏护理缺口
Sheng-Guang Li,Lina Zhang,Jing Zhang et al.
Sheng-Guang Li et al.
Background: Allergic diseases affect more than one billion people globally, yet care access is profoundly unequal. The "forgotten billion" refers to underserved populations-especially in LMICs and marginalized groups with...
An immunodominance perspective on a paradoxical phenomenon: discovery and modeling of ragweed and tree sensitization as negative predictors for high mugwort IgE reactivity [0.03%]
从免疫优势角度看待一个悖论现象：豚草和树木致敏作为高浓度艾属植物IgE反应的负向预测因子的发现与建模研究
Yuqiao Zhang,Xiyuan Yan,Fengxia Yang et al.
Yuqiao Zhang et al.
Background: Mugwort allergy poses a significant disease burden in Northwestern China. While sensitization to mugwort can be confirmed through specific IgE testing, the immunological factors that influence the intensity of...
Integrative skin-blood transcriptomic analysis identifies circulating biomarkers reflecting disease activity in atopic dermatitis [0.03%]
整合性皮肤-血液转录体分析鉴定出特应性皮炎疾病活动的循环生物标志物
Alberto Fernández-Bernaldez,Ana Jiménez-Sánchez,Pablo Chicharro et al.
Alberto Fernández-Bernaldez et al.
Background: Atopic dermatitis (AD) is characterized by complex immune dysregulation primarily studied in lesional skin. Identifying circulating molecular signatures that mirror cutaneous inflammation could enable non-inva...
Serological and biochemical characterization of Aspergillus fumigatus Asp f 10 as a potential diagnostic marker in ABPA and related respiratory diseases [0.03%]
烟曲霉菌Asp f 10的血清学和生化特性鉴定及其作为ABPA及相关的呼吸系统疾病的诊断标志物研究
Shramana Ghosh,Angira Dasgupta,Rajat Kanti Sarkar et al.
Shramana Ghosh et al.
Background: Aspergillus fumigatus is a major cause of allergic bronchopulmonary aspergillosis (ABPA), yet diagnosis remains challenging due to overlap with other atopic conditions. Asp f 10, a secreted aspartic protease, ...
Hemoglobin-to-Red cell distribution width ratio and asthma risk: cross-population validation and vitamin D mediation analysis [0.03%]
血红蛋白-红细胞分布宽度比率与哮喘风险：交叉人群验证及维生素D介导分析
Yanbiao Xiao,Jun Lai,Yanglin Zhang
Yanbiao Xiao
Purpose: This study aimed to explore the association between hemoglobin-to-red blood cell distribution width ratio (HRR) and asthma risk using a large U.S. population-based cohort (NHANES), and to validate the core associ...
Recent advances in biomarkers for efficacy assessment in allergen-specific immunotherapy [0.03%]
近年过敏特异性免疫治疗疗效评估生物标志物研究进展
Hong Huang,Dan Zeng
Hong Huang
Allergen-specific immunotherapy (AIT) is a disease-modifying therapeutic approach that addresses the fundamental etiology of allergic diseases by inducing immune tolerance through modulation of the immune system. Nevertheless, assessing AIT...