A new experimental model of peanut allergy in BALB/c and C57BL/6 mice [0.03%]
BALB/c和C57BL/6小鼠新的花生过敏实验模型研究
Marcos Felipe Andrade-Oliveira,Rafael Saavedra Langer,Sara Cândida Barbosa et al.
Marcos Felipe Andrade-Oliveira et al.
Introduction: Food allergy protocols are highly variable. While it allows the exploration of multiple scientific questions, it limits the possibility to make general assumptions and point out specific features of allergy ...
Esophageal tissue immunoglobulin G4 in eosinophilic esophagitis and its correlation with serum-specific IgG4 to six foods [0.03%]
嗜酸细胞性食管炎的食管组织免疫球蛋白G4及其与六种食物特异性IgG4的相关性研究
Eva Macías,Ana Menéndez-Ramos,Antonio Velasco-Guardado et al.
Eva Macías et al.
Background & aims: Eosinophilic esophagitis (EoE) is a chronic inflammatory disorder in which IgG4 involvement is unclear. We aimed to evaluate immunoglobulin G4 (IgG4) in eosinophilic esophagitis (EoE) and investigate th...
Risk factors for drug resistance in allergen immunotherapy for allergic rhinitis: a systematic review and meta-analysis [0.03%]
过敏性鼻炎免疫治疗药物耐受性的危险因素：系统评价和Meta分析
Zhi-Qiang Zhang,Jing-Yang Li,Jinyu Geng et al.
Zhi-Qiang Zhang et al.
Background: Allergen Immunotherapy (AIT) is largely considered to be the only therapy that can provide relief from allergic rhinitis (AR).Although its effectiveness has been confirmed by the results of a large number of p...
Specific IgE to tropomyosin increases the diagnostic accuracy of shrimp allergy [0.03%]
特异性IgE抗体检测肌动蛋白可提高虾过敏诊断的准确性
Prapasri Kulalert,Piyawut Kreetapirom,Surapon Piboonpocanun et al.
Prapasri Kulalert et al.
Purpose: Skin prick test (SPT) and the level of serum-specific IgE (sIgE) antibodies to shrimp have low specificity in the diagnosis of shrimp allergy. Measurement of sIgE to tropomyosin is available as a test, but the ac...
Clinical evaluation of pediatric olfactory disorders: a review from etiology to management [0.03%]
儿童嗅觉障碍的临床评估：从病因到治疗的综述
Eleonora M C Trecca,Marella Reale,Luca Leone et al.
Eleonora M C Trecca et al.
Olfactory perception plays a fundamental role in nutrition, emotional development, and social behavior, yet olfactory disorders (OD) in children remain largely underrecognized and understudied. This mini review summarizes current evidence a...
Case Report: Extending dosing intervals of biologics in adults severe asthma: a case series [0.03%]
成人重度哮喘生物制剂给药间隔延长的病例报告系列研究
Tomoya Harada,Miyu Nishigami,Hiroyuki Tanaka et al.
Tomoya Harada et al.
Background: Biological therapies have improved the control of severe asthma. However, biological therapies are expensive. Therefore, the cost-effective use of these medications after achieving improved disease control war...
MRGPRX2-expressing mast cells are increased in the GI tract of individuals with active inflammatory bowel disease and hereditary α-tryptasemia [0.03%]
MRGPRX2表达的肥大细胞在炎症性肠病活动期和遗传性α-精胺素血症患者的胃肠道中增加
Michelle Galeas-Pena,Jonathan J Lyons,Dhana Llivichuzhca-Loja et al.
Michelle Galeas-Pena et al.
Introduction: Hereditary α-tryptasemia (HαT), defined by increased TPSAB1 copy number and elevated basal serum tryptase, is associated with mast cell (MC)-mediated symptoms. However, its role in gastrointestinal disease...
Editorial: Exploring the interconnection: obesity's role in asthma development and management [0.03%]
述评：探索相互关联：肥胖在哮喘发生和发展中的作用
Akira Yamasaki,Katsuyuki Tomita
Akira Yamasaki
A randomized, double-blind, placebo-controlled trial of soluble corn fiber supplementation for children with asthma [0.03%]
哮喘儿童可溶性玉米纤维干预的随机双盲安慰剂对照试验研究
Matthew A Rank,Daisy L Barroso,Kathryn A Conn et al.
Matthew A Rank et al.
Introduction: Asthma is a multifactorial disease influenced by genetic and environmental factors, including diet. The gut microbiome contributes to airway inflammation via the gut-lung axis, partly through production of s...
Clinical Trial
Frontiers in allergy. 2026 Jan 21:6:1707834. DOI:10.3389/falgy.2025.1707834 2026
Biologic therapies for severe pediatric asthma: efficacy, safety, and biomarker-guided selection [0.03%]
儿科严重哮喘的生物疗法：疗效、安全性和生物标志物指导的选择
Enrico Tondina,Alessia Claudia Codazzi,Riccardo Castorina et al.
Enrico Tondina et al.
Background: Severe pediatric asthma is a heterogeneous, high-burden disease marked by variable corticosteroid responsiveness, frequent exacerbations, and substantial impairment in quality of life. Advances in airway immun...