EGFR inhibitors suppress house dust mite allergen Der pII induced inflammation in monocytes and macrophages [0.03%]
表皮生长因子受体抑制剂可抑制尘螨过敏原Der p II诱发的单核细胞和巨噬细胞炎症
Ya-Hui Chiang,I-Lun Hsin,Ping-Ju Chen et al.
Ya-Hui Chiang et al.
Introduction: Allergic asthma, often triggered by house dust mites (HDMs), is characterized by airway inflammation, mucus hypersecretion, and airway hyperresponsiveness. Among the major HDM allergens, Der pII plays a sign...
The knowledge, attitudes and practice of nasal irrigation among patients with rhinosinusitis: a cross-sectional study [0.03%]
鼻窦炎患者的鼻腔冲洗知识、态度及行为调查：横断面研究
Feng-Ling Yang,Biao Wang,Wei Deng et al.
Feng-Ling Yang et al.
Objective: Nasal inflammatory diseases significantly impair patients' quality of life, with global prevalence varying regionally. Nasal irrigation, endorsed by international guidelines as adjunctive therapy, lacks standar...
IgE, anti-IgE therapy, and regulatory T cells: new paradigms in allergic inflammation [0.03%]
IgE、抗IgE治疗和调节性T细胞：过敏性疾病的新模式
C Benito-Villalvilla,A Angelina,L Martín-Cruz et al.
C Benito-Villalvilla et al.
Allergic inflammation arises from a dysregulated immune response in which immunoglobulin E (IgE) plays a central pathogenic role. By binding to its high-affinity FcεRI on mast cells and basophils, IgE orchestrates the rapid activation and ...
Nasal eosinophilia and its clinical correlates in patients with allergic rhinitis at a Kenyan tertiary hospital [0.03%]
肯尼亚三级医院过敏性鼻炎患者的鼻腔嗜酸性粒细胞增多及其临床相关因素
Vivyane Wamara,Catherine Irungu,Musa Kipingor et al.
Vivyane Wamara et al.
Introduction: Allergic Rhinitis (AR) is an IgE- mediated inflammatory disease of the nasal mucosa. While the diagnosis mainly relies on a typical clinical history and physical examination, the evaluation of eosinophils in...
Editorial: Gut microbiota changes: a key driver of increased food allergy prevalence [0.03%]
述评：肠道微生物改变是食物过敏增加的关键原因
Ibrahim Musa,Maurizio Mennini
Ibrahim Musa
Safety of a novel oral immunotherapy approach in preschool children with single and multiple food allergies [0.03%]
一种新型口服免疫疗法治疗学龄前儿童单一和多种食物过敏的安全性
Lieke J C Barten,Joyce Faber,Kim Kamphorst et al.
Lieke J C Barten et al.
Background: Oral immunotherapy (OIT) has emerged as a promising food allergy treatment with significant evidence of increased efficacy in preschool-aged children. However, current OIT protocols are generally burdensome an...
Clinical Trial
Frontiers in allergy. 2026 Feb 2:7:1724759. DOI:10.3389/falgy.2026.1724759 2026
Andrea O&#x;Malley,Kriti Khatri,Elaine M Wright et al.
Andrea O&#x;Malley et al.
Calcium-binding proteins, particularly those in the EF-hand family, are found ubiquitously in nature, primarily for calcium transport and storage in the body. In this review, we discuss allergens in the parvalbumin, polcalcin, sarcoplasmic ...
The Spanish REAL project: expert allergist guidance on allergen immunotherapy based on mixtures from different allergenic sources [0.03%]
西班牙REAL项目：基于不同过敏原来源混合物的变应原免疫疗法专家指导
M Viñas,V Bellido,D El-Qutob et al.
M Viñas et al.
Background: The increase in polyallergy highlights allergen-specific immunotherapy (AIT) as a crucial therapeutic option for these patients. It is the only etiological treatment capable of modifying the natural course of ...
A shared metabolic-immune axis links local and systemic inflammation in chronic rhinosinusitis with comorbid asthma [0.03%]
慢性鼻窦炎伴发哮喘的局部和全身性炎症之间的代谢免疫轴联系研究
Xin Peng,Zhili Li,Yibo Liang et al.
Xin Peng et al.
Background: Chronic rhinosinusitis with nasal polyps (CRSwNP) comorbid with asthma (CRSwA) represents a severe "unified airway" phenotype, yet the metabolic mechanisms linking upper and lower airway inflammation remain un...
Impact of biologicals on revision ESS numbers in CRSwNP in a tertiary care rhinology center [0.03%]
生物制剂对三级耳鼻喉中心肉芽肿性鼻窦炎患者再次内镜下鼻窦手术数量的影响
Judith E Adriaenssens,An-Sofie Viskens,Elien Borgers et al.
Judith E Adriaenssens et al.
Background: Since 2022, several biologics are indicated and reimbursed for Belgian patients with severe uncontrolled CRSwNP despite previous endoscopic sinus surgery (ESS). Data on the impact of biologics on the number of...