Development and pilot validation of a chemiluminescence immunoassay for monitoring immunologic changes during peanut oral immunotherapy using sIgE/sIgG4 ratio [0.03%]
一种用于监测花生口服免疫治疗期间免疫变化的sIgE/sIgG4比率化学发光免疫测定法的建立和初步验证
Xiao Yang,Austin Vanderkallen,J Joanna Yu et al.
Xiao Yang et al.
Background: The sIgE/sIgG4 ratio has been proposed as a dynamic measure of immune modulation during peanut oral immunotherapy (OIT). This study evaluated a chemiluminescent immunoassay for simultaneous quantification of p...
Severe recurrent anaphylaxis: investigating underlying mechanisms beyond IgE-mediated allergy - a case report [0.03%]
重度反复性过敏性休克：一例超出了IgE介导的过敏反应的机制调查的病例报告
Agnieszka Gawlewicz-Mroczka,Ewelina Gacek,Natalia Zamorska et al.
Agnieszka Gawlewicz-Mroczka et al.
Anaphylaxis is a sudden, life-threatening, and generalized allergic reaction that develops within minutes to hours following exposure to an allergen. Cutaneous, respiratory, and cardiovascular symptoms may occur in various combinations, and...
Advances in clinical examination techniques for allergic rhinitis: a review from traditional testing to precision diagnosis [0.03%]
过敏性鼻炎临床检查技术进展：从传统检测到精准诊断的回顾分析
Xinyan Liu,Yongtai Wang,Hexiao Tian et al.
Xinyan Liu et al.
Allergic rhinitis (AR) is an IgE-mediated, non-infectious inflammatory disorder of the nasal mucosa, and accurate diagnosis is important for individualized treatment. Over the past decade, diagnostic strategies for AR have evolved substanti...
Tezepelumab attenuates exertional symptom burden in severe asthma: insights from a real-world cohort [0.03%]
tezepelumab减轻重度哮喘运动诱发的症状负担——真实世界队列研究的新见解
Slagjana Stoshikj,Katharina Marth,Daniela Boryshchuk et al.
Slagjana Stoshikj et al.
Background: Exertional symptom burden is an important yet insufficiently characterised component of morbidity in severe asthma. Tezepelumab, a monoclonal antibody targeting thymic stromal lymphopoietin (TSLP), reduces exa...
Effects of vitamin D levels and vitamin D supplementation on allergic diseases: an umbrella review [0.03%]
维生素D水平和维生素D补充剂对过敏性疾病的影响:伞式综述
Yuxin Hou,Qitong Zhang,Xianpeng Xu et al.
Yuxin Hou et al.
Background: The association between vitamin D levels/supplementation and the risk of allergic diseases has been extensively studied. However, the strength and consistency of the existing evidence remain unclear, and most ...
Yu Kyoung Hwang
Yu Kyoung Hwang
Allergic diseases are traditionally interpreted through epithelial barrier dysfunction, type 2 immune activation, and downstream inflammatory mediators, whereas routine serum lipid measures have usually been considered markers of cardiometa...
Improving prescriber confidence in COX-2 inhibitor use for aspirin-exacerbated respiratory disease: impact of a standard operating procedure [0.03%]
改善COX-2抑制剂使用的开具者的信心以治疗阿司匹林加重的呼吸系统疾病：标准操作程序的影响
Emily Hocknell,Peta-Lee Sacks,Ulka Vamadevan et al.
Emily Hocknell et al.
Introduction: Aspirin-exacerbated respiratory disease (AERD) presents a challenge in perioperative pain management. Many prescribers are uncertain about COX-2 inhibitor safety, leading to inconsistent prescribing practice...
The Chronic Angioedema Registry: what the first 2 years since the implementation of the global registry have taught us [0.03%]
慢性血管性水肿登记处：实施全球登记后的前两年教会了我们什么
Thomas Buttgereit,Mathias Sulk,Jonathan A Bernstein et al.
Thomas Buttgereit et al.
Background: The Chronic Angioedema Registry (CARE) is the first international, multicenter observational registry established to systematically collect clinical and patient-reported data from patients with recurrent angio...
Systemic immunologic effects of long-term dupilumab treatment in severe eosinophilic asthma beyond clinical outcomes [0.03%]
与临床结果无关的长期杜匹鲁单抗治疗重度嗜酸性粒细胞性哮喘的全身免疫效应
Sabina Škrgat,Luka Kunej,Urška Bidovec-Stojkovič et al.
Sabina Škrgat et al.
Introduction: Dupilumab, an IL-4Rα antagonist that blocks IL-4/IL-13 signalling, is used in severe eosinophilic asthma to improve clinical control and suppress type 2 inflammation. ...
Biologic-assisted immunotherapy for pediatric food allergy: a systematic review [0.03%]
儿童食物过敏的生物辅助免疫疗法：系统性回顾研究
Anthony Mayer
Anthony Mayer
Background: Food allergies affect up to 8% of children and are a major cause of anaphylaxis, reduced quality of life, and healthcare use. Oral immunotherapy (OIT) can induce desensitization but is limited by adverse react...