Case Report: Angiotensin converting enzyme inhibitors vs. angiotensin receptor blockers in the management of chronic hypertension: a case of lisinopril-induced rhinorrhea [0.03%]
个例报告：慢性高血压的治疗中，血管紧张素转换酶抑制剂与血管紧张素受体拮抗剂的不同效果：一例 Lisinopril 引发流鼻涕的病例研究
Alice A Amudzi,Giro Richard Samale,Xavier Vela-Parada
Alice A Amudzi
A 47-year-old woman presents to our clinic with a chief complaint of rhinorrhea; she had chronic hypertension managed with four antihypertensive drugs, including an ACE inhibitor. While dry cough is a well-known side effect associated with ...
Pediatric eosinophilic esophagitis: a Belgian single-center retrospective analysis reveals real-life difficulties in diagnosis and treatment [0.03%]
比利时单中心回顾性分析显示儿科嗜酸细胞性食管炎的诊断和治疗困难
Toon Dominicus,Lisa Nuyttens,Ilse Hoffman et al.
Toon Dominicus et al.
Introduction: Eosinophilic esophagitis (EoE) is a chronic immune-mediated disorder characterized by eosinophilic infiltration of the esophageal mucosa. Me...
Baricitinib as monotherapy and with topical corticosteroids in moderate-to-severe atopic dermatitis: a systematic review and meta-analysis of dose-response [0.03%]
巴利西单抗作为单药治疗和与外用皮质类固醇联合治疗中至重度特应性皮炎：剂量反应的系统评价和meta分析
Ibrahim H I Almoghayer,Abdul Mateen Soomro,Shah Dev et al.
Ibrahim H I Almoghayer et al.
Introduction: Atopic dermatitis (AD) is a chronic inflammatory skin disorder that affects millions worldwide, presenting challenges in managing symptoms and quality of life. Current treatments include topical corticostero...
Hereditary alpha tryptasemia: elevated tryptase, female sex, thyroid disorders, and anaphylaxis [0.03%]
遗传性α-肥大细胞增多症：血清中触酶水平升高、女性性别、甲状腺疾病和过敏反应之间的关联
Viktoria Puxkandl,Stefan Aigner,Wolfram Hoetzenecker et al.
Viktoria Puxkandl et al.
Introduction: The clinical significance of elevated baseline serum tryptase (BST) in the absence of mast cell disorders or allergic reactions has long been unclear. Recently, a genetic variation of the TPSAB1 gene, which ...
Assessing the predictive potential of ADAM8 for disease control in chronic rhinosinusitis with nasal polyps [0.03%]
评估ADAM8在慢性鼻窦炎伴鼻息肉疾病控制中的预测潜力
Peiqiang Liu,Meng Liu,Yibin Sun et al.
Peiqiang Liu et al.
Background: A disintegrin and metalloproteinase 8 (ADAM8) has been implicated in eosinophilic inflammation; however, its role in chronic rhinosinusitis with nasal polyps (CRSwNP) remains to be elucidated. This study aimed...
Dominic S H Wong,Alexandra F Santos
Dominic S H Wong
Food allergy represents an increasing global health issue, significantly impacting society on a personal and on a systems-wide level. The gold standard for diagnosing food allergy, the oral food challenge, is time-consuming, expensive, and ...
Unraveling heterogeneity and treatment of asthma through integrating multi-omics data [0.03%]
通过整合多组学数据解析哮喘的异质性与治疗方式
Wei Zhang,Yu Zhang,Lifei Li et al.
Wei Zhang et al.
Asthma has become one of the most serious chronic respiratory diseases threatening people's lives worldwide. The pathogenesis of asthma is complex and driven by numerous cells and their interactions, which contribute to its genetic and phen...
Andrew C Retzinger,Gregory S Retzinger
Andrew C Retzinger
The Acari Hypothesis posits that acarians, i.e., mites and ticks, are operative agents of allergy. It derived from observations that allergens are molecular elements of acarians or acarian foodstuffs. A corollary of The Hypothesis provides ...
Case Report: Anaphylaxis caused by traditional Chinese medicine in a patient with pollinosis [0.03%]
病例报告：一名患有过敏性鼻炎的患者因服用中药导致过敏性休克
Zhouxian Pan,Mengyuan Zhan,Qing Wang et al.
Zhouxian Pan et al.
This case describes a patient with anaphylaxis caused by traditional Chinese medicine. Skin prick test with the traditional Chinese medicine decoction indicates that he was allergic to Suan Zao Ren. The patient had pollinosis and had never ...
Case Report: Dual monoclonal antibody therapy in chronic rhinosinusitis with nasal polyps and severe eosinophilic asthma-a proteome analysis [0.03%]
病例报告：慢性鼻窦炎合并鼻息肉和重度嗜酸性粒细胞性哮喘的双特异抗体治疗-蛋白组分析
Manon Blauwblomme,Philippe Gevaert,Sharon Van Nevel et al.
Manon Blauwblomme et al.
Context: Recent insights into type 2 inflammation have led to the development of monoclonal antibody therapies for severe asthma and chronic rhinosinusitis with nasal polyps (CRSwNP). Despite add-on therapy with a monoclo...