Clinical characteristics and treatment of unilateral allergic fungal rhinosinusitis: a retrospective case series and literature review [0.03%]
单侧过敏性真菌性鼻窦炎的临床特征及治疗：病例系列研究和文献综述
Xiaodong Chen,Jiawei Chen,Jian Wang et al.
Xiaodong Chen et al.
To retrospectively summarize the clinical manifestations, pathological characteristics, and efficacy of unilateral allergic fungal rhinosinusitis (AFRS), we analyzed the clinical data of 23 patients diagnosed with unilateral AFRS in a teach...
Real world evidence of dupilumab effectiveness in a Colombian cohort of patients diagnosed with severe asthma [0.03%]
杜匹鲁单抗治疗重度哮喘的哥伦比亚患者队列的有效性现实世界证据
Abraham Alí-Munive,Josefina Zakzuk,Nelson J Alvis-Zakzuk et al.
Abraham Alí-Munive et al.
Background: Real-world effectiveness and safety of dupilumab for asthma treatment have been evaluated in USA and Europe, but research from Latin America is lacking. We aimed to describe the effectiveness of dupilumab in t...
Defining "Normal" basal serum tryptase levels: a context-dependent approach to improve diagnostics in systemic mastocytosis [0.03%]
定义系统性肥大细胞增多症诊断中“正常”的基础血清组织胺水平：一种以情境为基础的方法
Francesca Crupi,Jessica Caroprese,Francesco Mannelli
Francesca Crupi
Serum tryptase level has long been used as a biomarker in clinical practice to suspect mast-cell associated disorders. Basal serum tryptase (BST) above 20 ng/ml represents a minor criterion according to WHO and ICC for the diagnosis of syst...
Multi-omics technology reveals the changes in gut microbiota to stimulate aromatic amino acid metabolism in children with allergic rhinitis and constipation [0.03%]
多组学技术揭示了肠道菌群变化可促进过敏性鼻炎伴便秘儿童芳香族氨基酸代谢激活
Chunyan Wang,Haiying Liu,Xiaoli Li et al.
Chunyan Wang et al.
Background: Comorbid allergic rhinitis and constipation (ARFC) in children are associated with gut microbiota (GM) dysbiosis and metabolic perturbations; however, the underlying mechanistic interplay remains unclear. ...
Effect of seasonal exposure in aeroallergen-sensitised patients with irritable bowel syndrome-diarrhoea [0.03%]
季节性接触对易感肠道易激综合征-腹泻患者的影響
Carlo Maria Rossi,Marco Vincenzo Lenti,Stefania Merli et al.
Carlo Maria Rossi et al.
Background: Pollen allergy may influence irritable bowel syndrome (IBS) symptoms; however, available data are scant. Aims: This study a...
A deep dive into shrimp allergy: clinical spectrum of shrimp allergy in a Tunisian pilot study [0.03%]
一次深入的虾过敏研究：一项针对突尼斯受试者的研究中虾过敏的临床症状
Dhouha Krir,Imen Zamali,Yousr Galai et al.
Dhouha Krir et al.
Shrimp allergy has emerged as a growing health concern in Tunisia, likely due to changing dietary habits. This study aimed to characterize the clinical features of shrimp-allergic patients and investigate potential cross-reactivity with hou...
T2 cytokine-driven alarmin and antiviral responses in asthma: insights into immune modulation and the role of IL-4Rα targeting [0.03%]
哮喘中由T2细胞因子驱动的alarmin和抗病毒反应：免疫调节及IL-4Rα靶向作用的新见解
Jelena Pesic,Juan José Nieto-Fontarigo,Katerina Pardali et al.
Jelena Pesic et al.
Introduction: Severe asthma is a heterogeneous condition characterized by distinct phenotypes and endotypes based on clinical or biological characteristics. Interleukin (IL) 4 and IL-13 are central cytokines in the type 2...
The changing epidemiology of paediatric childhood asthma and allergy in different regions of the world [0.03%]
全球不同地区儿童哮喘和过敏流行病学的变化
D J Adamko,Kyla J Hildebrand
D J Adamko
Allergic disorders encompass a variety of conditions including asthma, atopic dermatitis, food allergy, allergic rhinitis, and eosinophilic esophagitis. These atopic disorders are connected via an abnormal host immune response to the enviro...
Case Report: Identification of a novel mutation, c.1067T > A, in the SERPING1 gene in a Chinese male with type 1 hereditary angioedema [0.03%]
案例报告：在一名中国男性1型遗传性血管水肿患者中识别出SERPING1基因新突变c.1067T>A
Wenjin Du,Ke Yang,Qiuxing Zhang et al.
Wenjin Du et al.
Hereditary angioedema (HAE) is a rare autosomal dominant genetic disorder characterized by recurrent, unpredictable episodes of angioedema that commonly involve the face, limbs, respiratory tract, and gastrointestinal tract. Clinical presen...
Editorial: The socio-economic burden of food allergy: from households to healthcare systems [0.03%]
论著：食物过敏的经济社会负担：从家庭到医疗体系
Jennifer L P Protudjer,Lucy A Bilaver
Jennifer L P Protudjer