Multiplex IgE peanut panels: a critical appraisal of assay designs and the good, the bad, and the ugly features of the applied allergen components [0.03%]
多重花生IgE检测：对所应用过敏原组分的测定设计及优劣特点的评价
D de Boer,C J J Bijnens,M C Slot et al.
D de Boer et al.
Background: Multiplex allergy assays are currently well-established in allergy diagnostics. However, the different assays in terms of designs and performance are also claimed to be heterogeneous as no agreed standards and...
Enhancing allergy diagnosis: mass spectrometry as a complementary technique to the basophil activation test [0.03%]
过敏诊断技术的改进——质谱技术作为basophil活化试验的补充方法
Nicole Wheeler,Miloslav Sanda,Lanya Rasool et al.
Nicole Wheeler et al.
Accurate diagnostic tools for allergic conditions are essential for effective treatment. Traditional methods, such as skin prick tests (SPT) and specific IgE measurements are widely used, but they have limitations in sensitivity and specifi...
Fluticasone propionate in chronic rhinosinusitis with nasal polyps (CRSwNP): an artificial intelligence-driven consensus [0.03%]
人工智能驱动的慢性鼻窦炎伴鼻息肉(CRSwNP)患者使用氟替卡松丙酸酯共识陈述
Emilio Avallone,Raffaella Iannella,Antonella Di Lullo et al.
Emilio Avallone et al.
Introduction: Fluticasone propionate (FP) is a topical corticosteroid used to treat rhinosinusitis with nasal polyposis (CRSwNP). However, the need for a consensus on its use stems from the increasing focus on optimizing ...
Utility of tryptase genotyping in the screening, diagnosis, and management of systemic mastocytosis [0.03%]
系统性肥大细胞增生症筛查、诊断和治疗中对血清组胺N-甲酰化的 utility
Jeremy C McMurray,Brandon J Schornack,Joaquin Villar et al.
Jeremy C McMurray et al.
Tryptase genotyping has an expanding role in the screening, diagnosis, and management of patients with systemic mastocytosis (SM). Reference ranges for basal serum tryptase (BST) based on increased TPSAB1 gene copy number can guide whether ...
R Maximiliano Gomez,Beré Kezia Mahoney
R Maximiliano Gomez
Steroid-sparing benefits of biologic use in hypereosinophilic syndrome and substantial disease burden across subtypes [0.03%]
生物制剂在高嗜酸性粒细胞综合征中的糖皮质激素节省效益及不同类型疾病负担的评估
Jeremiah Hwee,Lynn Huynh,Wilson da Costa Jr et al.
Jeremiah Hwee et al.
Background: Limited data exist on the burden of myeloproliferative, lymphocytic and idiopathic subtypes of hypereosinophilic syndrome (M-HES, L-HES and I-HES) and the characteristics of patients with HES receiving biologi...
Editorial: Preventing childhood asthma-the neglected impact of existing public health interventions [0.03%]
预防儿童哮喘——现有公共卫生干预措施的 neglected 影响不容忽视
David M Patrick,Stuart E Turvey,Meghan B Azad et al.
David M Patrick et al.
Abigail Lang
Abigail Lang
Food allergy (FA) and hereditary alpha-tryptasemia (HαT) are both relatively common conditions, but potential associations between these diagnoses have not been well-studied. Prior studies have suggested that acute rises in tryptase follow...
The safety and efficacy of oral immunotherapy compared to epicutaneous immunotherapy in peanut allergen desensitisation amongst the paediatric cohort-a narrative review [0.03%]
口服免疫疗法与儿科花生过敏脱敏表皮免疫疗法的安全性和有效性的比较-综述性文章
Ehtesam A Chowdhury,Olivia C Jadeja
Ehtesam A Chowdhury
Peanut allergies result from a type 1 hypersensitivity reaction, with a prevalence of approximately 1% in children under 5 years of age. The allergens that instigate this reaction are the peanut proteins (Ara h 1-Ara h 8) for which IgE anti...
Study protocol for a randomized double-blinded placebo-controlled trial on ASA therapy for patients with chronic rhinosinusitis with nasal polyps, NSAID-exacerbated respiratory disease, and asthma [0.03%]
阿司匹林治疗慢性鼻窦炎合并鼻息肉、非甾体抗炎药加重性呼吸系统疾病及哮喘患者的随机双盲安慰剂对照研究方案
Sanna Toppila-Salmi,Annina Lyly,Viljami Salmi et al.
Sanna Toppila-Salmi et al.
Background: Chronic rhinosinusitis with nasal polyps (CRSwNP) is a chronic inflammatory condition affecting the nasal passages and paranasal sinuses. It is characterized by persistent inflammation and often leads to a con...