Inhalation and inflammation: examining aeroallergens and eosinophilic esophagitis [0.03%]
吸入与炎症：探究气传过敏原和嗜酸性粒细胞食管炎的关系
Sitharthan Sekar,Kate Kelly,Dipa Sheth et al.
Sitharthan Sekar et al.
Eosinophilic esophagitis (EoE) is a chronic immune-mediated disease leading to inflammation in the esophageal lining. EoE has become a significant cause of gastrointestinal illness in both children and adults. While there is significant foc...
Efficacy and limitations of systemic corticosteroids in patients with CRSwNP compared to alternative therapies with monoclonal antibodies: real-life of 101 patients from the Lazio region, Italy [0.03%]
与使用单克隆抗体的替代疗法相比，皮质类固醇在CRSwNP患者中的疗效和局限性：意大利拉齐奥地区101例患者的现实情况分析
F Anastasi,C Di Nota,S Sessi et al.
F Anastasi et al.
Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) is a chronic inflammatory disease. Its severe uncontrolled form may share, with asthma and atopic dermatitis, the pathophysiological mechanism of T helper 2 inflammation, characterized by ti...
Clinical efficacy on acupuncture for perennial allergic rhinitis: a study protocol for a randomized clinical trial [0.03%]
针刺治疗常年性过敏性鼻炎的临床疗效研究方案：一项随机对照试验研究报告
Jia-Xin Yang,Shu-Ren Ming,Hui Chen et al.
Jia-Xin Yang et al.
Background: Allergic rhinitis (AR) is a prevalent allergic disorder. Acupuncture has been widely utilized to alleviate allergic symptoms, and numerous studies have investigated its therapeutic effects on AR. However, due ...
Non allergic gastrointestinal manifestations of hereditary alpha-tryptasemia [0.03%]
遗传性α-胰蛋白酶血症的非过敏性胃肠表现
Dylan Vainer,Kathryn Peterson
Dylan Vainer
Hereditary alpha-tryptasemia (HαT) is an autosomal dominant genetic trait characterized by elevated basal serum tryptase due to increased TPSAB1 gene copy numbers. Affecting approximately 4%-6% of the Caucasian population, HαT is associat...
Platelet-to-high-density lipoprotein ratio as a biomarker for asthma risk in adolescents: insights from NHANES 2011-2023 [0.03%]
血小板与高密度脂蛋白比率作为青少年哮喘风险生物标志物：来自NHANES 2011-2023的见解
Fangju Liao,Qi Lv,Yana Xu et al.
Fangju Liao et al.
Background: Asthma is a common inflammatory disease among adolescents, with systemic inflammation playing a key role in its development. The platelet-to-high-density lipoprotein ratio (PHR) has emerged as a novel indicato...
Epigenetic modifications are associated with mRNA and cytokine expression changes in chronic rhinosinusitis: a multiomics study from the United States [0.03%]
表观遗传修饰与慢性鼻窦炎的信使rna和细胞因子表达变化相关性研究：一项美国多组学研究报告
Devyani Lal,Tripti Brar,Chantal McCabe et al.
Devyani Lal et al.
Objectives/hypothesis: Chronic rhinosinusitis (CRS) may be triggered by environmental insults. We hypothesized that CRS results from epigenetic modifications of host DNA from external insults, leading to downstream RNA/DN...
Efficacy of index of reactivity-liquid sublingual immunotherapy in allergic rhinoconjunctivitis: a systematic review and meta-analysis of randomized studies [0.03%]
变应性鼻结膜炎活性反应指数-液体亚舌下免疫治疗疗效的系统评价和meta分析
Danilo Di Bona,Andrea Di Biase,Giovanni Paoletti et al.
Danilo Di Bona et al.
Introduction: Allergen immunotherapy (AIT) is a well-established treatment with demonstrated efficacy and safety. However, variability in study outcomes remains a challenge, driven by differences in patient characteristic...
From skin testing to molecular diagnostics: the precision leap in dust mite allergy diagnosis and clinical translation challenges [0.03%]
从皮肤点刺试验到分子诊断：尘螨过敏精准诊疗的发展及临床转化挑战
Ming Han,Jindan Luo,Wenjing Zhou et al.
Ming Han et al.
Dust mites are ubiquitous in human living environments and represent the primary source of indoor air allergens worldwide. They are capable of triggering allergic rhinitis, conjunctivitis, asthma, atopic dermatitis, and other allergic condi...
Acute airway eosinophilic inflammation model in mice induced by ovalbumin, house dust mite, or shrimp tropomyosin: a comparative study [0.03%]
卵清蛋白、粉尘螨和虾热激蛋白诱导小鼠急性气道嗜酸性粒细胞炎症模型的比较研究
Liangyu Xu,Zichen Wei,Rongfang Wu et al.
Liangyu Xu et al.
Background: Ovalbumin (OVA) and house dust mite (HDM) are widely used allergenic proteins in murine models of allergic asthma. In our previous studies, shrimp tropomyosin (ST) was shown to induce type I hypersensitivity, ...
Yuanli Guo,Manli Qi,Jinluan Ding
Yuanli Guo
Background: Hereditary angioedema (HAE) is a life-threatening condition characterized by repeated asymmetric cutaneous and mucosal edema. It is a rare autosomal dominant genetic disease with a mortality rate of 8.6%. Fami...