Diana C Yánez,Ching-In Lau,Jasmine Rowell et al.
Diana C Yánez et al.
The Forkhead box A (FOXA) transcription factors are pioneer factors that orchestrate diverse cellular and developmental processes. Within the respiratory system, FOXA1, FOXA2, and FOXA3 have emerged as modulators of pulmonary inflammation, ...
Depemokimab demonstrates efficacy in patients with type 2 asthma with comorbid CRSwNP: Phase III SWIFT-1/-2 analysis [0.03%]
Enrico Heffler,Diana Jarreta,Chang-Qing Zhu et al.
Enrico Heffler et al.
Introduction: The efficacy of twice-yearly depemokimab was demonstrated in the Phase III SWIFT-1/-2 trials for type 2 asthma characterized by blood eosinophils, and ANCHOR-1/-2 trials for chronic rhinosinusitis with nasal...
S Lau,V Backer,G K Scadding et al.
S Lau et al.
EUFOREA, the European Forum for Research and Education in Allergy and Airways diseases, is an international non-for-profit organisation of physicians, patients, and other stakeholders committed to the improvement of outcomes for patients su...
Comparison of rapid and same-day desensitization protocols in hypersensitivity reactions to platinum and taxanes: a retrospective cohort study [0.03%]
María Cruz Torres Górriz,Julián Borrás Cuartero,Paula Viedma Ayllón et al.
María Cruz Torres Górriz et al.
Background: Rapid drug desensitization (RDD) allows first-line treatment to continue after a hypersensitivity reaction to the antineoplastic agent. There are different desensitization procedures, and none of them are free...
Understanding disease burden, challenges in current treatment strategies and call for action for management of severe asthma in Asia: a position statement from Asian respiratory experts [0.03%]
亚洲呼吸病专家关于亚太地区重度哮喘疾病负担、现有治疗策略挑战及应对声明
Mariko Siyue Koh,Ken Ka Pang Chan,Koichi Fukunaga et al.
Mariko Siyue Koh et al.
In the Asia-Pacific region, there is limited data on the full extent of the burden of severe asthma, as well as a lack of clear guidance on improving care standards. Genetic, environmental, behavioural, policy and funding factors in -Asia-P...
Histopathological alterations in airways associated with physiological changes in airway allergy phenotypes [0.03%]
与气道过敏表型生理改变相关的气道组织病理学改变
Marisol Alvarez-González,Angélica Flores-Flores,Ivonne Pacheco-Alba et al.
Marisol Alvarez-González et al.
Introduction: Ovalbumin sensitization in guinea pigs induces diverse allergic responses. The asthma model exhibits airway obstruction, hyperresponsiveness, fibrosis, and reduced airway caliber, associated with elevated β...
Yiming Di,Ruizhi Zeng,Lei Huang et al.
Yiming Di et al.
Managing chronic rhinosinusitis with nasal polyps (CRSwNP) poses challenges, especially when conventional treatments fail to achieve adequate symptom control. CRSwNP is often marked by type 2 inflammation, and a large number of patients hav...
Clinical observation of stapokibart in patients under 18 years of age with seasonal allergic rhinitis: a case series study of 20 cases [0.03%]
司巴汀颗粒治疗18岁以下季节性过敏性鼻炎患者的临床观察（病例系列）
Long-Fei Wang,Wei-Cong Ma,Chen-Xing Kan et al.
Long-Fei Wang et al.
Objective: The objective of this work was to investigate the efficacy and safety of stapokibart, an anti-IL-4Rα monoclonal antibody, in patients under 18 years of age with moderate-to-severe seasonal allergic rhinitis (S...
Long-term Qipian® administration confers resistance to airway inflammation in OVA-induced asthmatic mice [0.03%]
Qipian®长期给药可以改善卵清蛋白致敏小鼠哮喘炎症反应
Huiying Wang,Ru-Yi Chen,Jin-Jin Shi et al.
Huiying Wang et al.
Background: Qipian® is an immunomodulatory agent with established short-term benefits in allergic asthma, but its long-term effects remain unclear. This study aimed to investigate its potential to attenuate the developme...
IgE-defined endotypes reveal distinct clinical profiles of prurigo nodularis compared with atopic dermatitis: a multicenter study in China [0.03%]
基于IgE的亚型揭示了皮瘤性皮炎与特应性皮炎不同的临床特征：中国多中心研究
Shihua Ling,Yan Liao,Chaofeng Chen et al.
Shihua Ling et al.
Background: Prurigo nodularis (PN) is a chronic inflammatory dermatosis that often coexists with atopic dermatitis (AD) but represents a distinct entity. Evidence directly comparing PN and AD in Chinese populations remain...