Antibiotic therapy as a risk factor for chronic residual and phantom limb pain after combat-related amputation: a 212-patient cohort study [0.03%]
抗生素治疗与战斗相关的截肢后残余痛和幻肢痛的危险因素：一项涉及212名患者的研究
Kateryna Ksenchyna,Oleh Ksenchyn,Oleksandr Nazarchuk et al.
Kateryna Ksenchyna et al.
Background: Antibiotic (AB) therapy is standard in managing combat-related infections, particularly after traumatic limb amputations. However, prolonged or combined antibiotic regimens may contribute to neuroinflammatory ...
Exclusion criteria in clinical trials of treatments for neuropathic pain: a systematic analysis [0.03%]
神经病理性疼痛治疗临床试验的排除标准：系统分析
Raymundo Salcedo,Reihaneh Moghadam,Sahar Saneifard et al.
Raymundo Salcedo et al.
Introduction: Clinical trials for neuropathic pain often employ strict exclusion criteria that may limit the generalizability of their findings to real-world clinical populations. This study systematically analyzed the na...
Artemin/GFRA3 axis and TRP channels: molecular insights from a feline model of osteoarthritis [0.03%]
动脉蛋白/GFRA3轴和TRP通道：来自猫骨关节炎模型的分子见解
Joshua J Wheeler,Chie Tamamoto-Mochizuki,Margaret E Gruen et al.
Joshua J Wheeler et al.
Introduction: Degenerative Joint Disease (DJD) is a form of highly prevalent osteoarthritis in humans and animals, including cats, which causes significant pain and hypersensitivity. Despite its prevalence, the mechanisms...
Determinants of adherence and safety in fully autonomous home-based transcranial direct current stimulation for fibromyalgia [0.03%]
家庭基于的纤维肌痛自主经颅直流电刺激的影响及安全性因素研究
Wolnei Caumo,Lucas Bohrer Flores,Isabela Souza Fontoura et al.
Wolnei Caumo et al.
Background: Autonomous home-based transcranial direct current stimulation (HB-tDCS) is a scalable non-pharmacological intervention for chronic pain, but evidence under fully autonomous use remains limited. ...
A tonic electrocutaneous stimulation paradigm for graded sensory C-fiber engagement in healthy subjects [0.03%]
健康受试者分级感觉C纤维参与的电导刺激范式
Youngsun Kong,Andrew G Peitzsch,Riley Q McNaboe et al.
Youngsun Kong et al.
Introduction: Long-term pain models provide valuable proxies for studying physiological changes associated with chronic pain, which is commonly associated with sustained C-fiber-mediated nociceptive input and central sens...
Integrated multi-omics elucidates the dual anti-inflammatory and neuroendocrine mechanisms of novel TCM plasters against primary dysmenorrhea [0.03%]
整合多组学阐明新研制外用膏药治疗原发性痛经的抑炎及调脑作用机制
Weihui Liang,Wenxuan Cao,Yuan Zheng et al.
Weihui Liang et al.
Background: Primary dysmenorrhea (PD) is a prevalent gynecological condition primarily driven by uterine inflammation and hormonal imbalances. While non-steroidal anti-inflammatory drugs (NSAIDs) are the first-line treatm...
Beyond nociception: rethinking pain in ovarian endometriosis a pilot study [0.03%]
超越 nociception：卵巢子宫内膜异位症疼痛的重新思考——一项初步研究
Amira Quevedo,Mackenzie S Dyrda,Terrie Vasilopoulos et al.
Amira Quevedo et al.
Background: Endometriosis affects 1 in 10 women, is the most common cause of chronic pelvic pain, classically known for its nociceptive pain mechanisms. Medical therapies have limited efficacy, prevent pregnancy, and can ...
Impact of therapeutic exercises on pain-related outcomes in patients with knee osteoarthritis: an umbrella review of 116 systematic reviews [0.03%]
锻炼对膝关节炎患者的疼痛相关结果的影响：116项系统评价的伞式评审
Dmitriy Viderman,Sultan Kalikanov,Akerke Mazhibiyeva et al.
Dmitriy Viderman et al.
Background and objectives: Chronic knee pain is highly prevalent in various knee diseases. It significantly decreases patients' quality of life. Among non-surgical interventions, exercise is considered a promising approac...
Vineeta Singh,Anand Kumar,Sucharita Ray et al.
Vineeta Singh et al.
Background: Migraine is a neurological condition resulting from intricate connections among cerebral excitability, the nervous system, muscular function, and the body's stress response. For various reasons, complementary ...
The importance of partnership in chronic pain - co-creation of tomorrow's pain care by working together in research, implementation, and knowledge dissemination [0.03%]
慢性疼痛管理中的合作精神——通过研究、实施和知识传播共创未来的疼痛治疗体系的重要性
Paulin Andréll,Birgit Heckemann,Anna Grimby-Ekman et al.
Paulin Andréll et al.
Chronic pain is a long-term condition that affects the daily lives, identities, and well-being of millions of people worldwide. Effective pain care remains limited. Moreover, lack of knowledge and awareness among healthcare professionals an...