The effects of pulsed radiofrequency stimulation on mitochondrial function in neurons: a mini review [0.03%]
脉冲无线电频率刺激对神经元线粒体功能的影响:综述
Lukas D Linde,Paul Potgieter,Petra van Blerk et al.
Lukas D Linde et al.
Pulsed radiofrequency (PRF) stimulation is a widely used clinical intervention for neuropathic pain. Unlike continuous radiofrequency (CRF) ablation, PRF is non-destructive, yet its precise mechanism of action remains under debate. Emerging...
Chronic pain as a state-constrained brain network disorder: a dynamical systems model integrating physiological regulation and self-organisation [0.03%]
慢性疼痛作为受大脑网络状态约束的紊乱:一个整合生理调节和自我组织的动力系统模型
Tim Ho,Mark Ryan
Tim Ho
Chronic pain is increasingly understood as a disorder of large-scale brain network organisation rather than a direct consequence of persistent nociceptive input. Neuroimaging studies have consistently identified alterations in the salience ...
Pain sensitization as a potentially modifiable factor in people with knee osteoarthritis: insights from behavioral graded activity [0.03%]
膝骨关节炎患者痛觉敏感性增高的潜在可变性因素:行为分级活动的启示
Takafumi Hattori,Takako Matsubara
Takafumi Hattori
Introduction: Exercise is a first-line treatment for knee osteoarthritis (KOA); however, a substantial proportion of patients show a limited response to standardized exercise programs. Pain sensitization is increasingly r...
Short-term efficacy of physical interventions for lateral epicondylitis: a network meta-analysis based on multidimensional evaluation of pain and function [0.03%]
基于多维度评估短期物理治疗侧副韧带炎疗效的网状meta分析研究
Yu-Hong Song,Jin-Yan Lan,He-Hui Fu et al.
Yu-Hong Song et al.
Background: Lateral epicondylitis (LE) is a prevalent chronic tendinopathy that significantly impairs upper limb function and quality of life. This network meta-analysis (NMA) aims to evaluate and compare the short-term (...
Feasibility and reliability of pressure algometry for mechanical nociceptive threshold quantification in lambs in a field environment [0.03%]
基于压力 algometry 的机械痛阈量化在放牧环境下的可行性与可靠性研究
Charlotte Helen Johnston,Danila Marini,Stefan T Musolino et al.
Charlotte Helen Johnston et al.
Objective: To validate a modified algometer method for assessing mechanical nociceptive threshold (MNT) in lambs before and after husbandry procedures (marking) under field conditions by testing the precision, intra-opera...
Integrated machine learning and multi-omics analysis identifies CYP1B1 as a candidate target of orientin in intervertebral disc degeneration-associated low back pain [0.03%]
集成机器学习和多组学分析识别CYP1B1为髓核细胞中orientin靶标候选物:与椎间盘退行性病变相关背痛的研究
Hai-E Liu,Dong-Dong Guo,Kun Liu et al.
Hai-E Liu et al.
Objectives: Orientin is a bioactive agent isolated from natural resources successfully applied for pain control. This study was to explore candidate hub gene of orientin to intervertebral disc degeneration (IDD) -associat...
The impact of the 5A nursing model on pain in patients with postherpetic neuralgia: a randomized controlled trial [0.03%]
5A护理模式对带状疱疹后神经痛患者疼痛的影响:一项随机对照试验
Xi Yi
Xi Yi
Background: The complex pathogenesis of postherpetic neuralgia significantly impacts patients' quality of life. Traditional nursing models often fail to fully meet patients' individual needs, whereas the 5A nursing model ...
Phenotyping of isolated mesh associated pain secondary to continence mesh device insertion [0.03%]
盆底网片植入后导致的孤立网片相关的疼痛表型研究
Hawra Badri,Karen Ward,Richard Edmondson et al.
Hawra Badri et al.
Introduction: Isolated Mesh associated Pain Syndrome (I-MAPS) is the most common complication of continence mesh devices. The pain mechanism involved remains unknown. The aim of this study is to characterise the phenotype...
The time-effect relationship of intra-articular ozone injection for knee osteoarthritis: a systematic review and meta-analysis [0.03%]
膝骨关节炎玻璃体内注射臭氧的量效关系:系统评价和网络meta分析
Fengjiao Chen,Yufeng Tao,Jing Deng et al.
Fengjiao Chen et al.
Background: As a gradual degenerative illness, knee osteoarthritis (KOA) is characterized by high rates of impairment and prevalence. Patients' quality of life is seriously jeopardized, and healthcare systems and social a...
Pressure point: blood flow restriction exercise and the pain paradox in musculoskeletal injury and persistent pain populations-a narrative review [0.03%]
痛点:肌肉骨骼损伤和慢性疼痛人群中的血压限制锻炼与疼痛悖论-叙述性综述
Luke Gray,Luke Hughes,Lynn Kelly et al.
Luke Gray et al.
Musculoskeletal injuries are commonly accompanied by acute and persistent pain; the latter of which can lead to maladaptive neurophysiological changes including central sensitisation and altered pain modulation responses. Blood flow restric...