Electroacupuncture therapy and bone cancer pain relief: experimental study on analgesic mechanisms in rats [0.03%]
电针疗法与骨癌痛觉缓解：大鼠镇痛机制的实验研究
Yanhua Li,Fangfei Li,Caizhi Xiao et al.
Yanhua Li et al.
Background: Bone cancer pain is a common complication of advanced malignant tumors.Chemotherapeutic drugs, regardless of their origin or type, are often associated with various adverse effects such as gastrointestinal tox...
Extreme pulse dosing of 10 kHz spinal cord stimulation: how low can you go? [0.03%]
10kHz脊髓刺激的极低脉冲剂量：还有更低吗？
Mayank Gupta,Amy Reinert,C O West et al.
Mayank Gupta et al.
Background: Pulse dosing of high frequency spinal cord stimulation at 10 kHz (10 kHz SCS) may offer comparable clinical benefits as continuous 10 kHz SCS, but extreme pulse dosing (EPD) has not been studied. ...
Migraine is associated with a higher risk of ischemic and hemorrhagic stroke: an analysis of the All of Us database [0.03%]
偏头痛与缺血性和出血性卒中的风险增加有关：来自“全民参与”数据库的分析
Nick Seah,Catherine D Chong,Oana M Dumitrascu et al.
Nick Seah et al.
Background: While prior studies suggest an increased risk of stroke among individuals with migraine, particularly those with migraine with aura, data on how specific migraine characteristics and comorbidities influence th...
Primary somatosensory cortex oscillations in trigeminal neuralgia: laser-evoked signatures and their potential relevance to microvascular decompression [0.03%]
三叉神經痛的 primary somatosensory皮层振荡：激光诱发特征及其对显微血管减压术的意义
Britta N Kretzschmar,André Rupp,Sandro M Krieg et al.
Britta N Kretzschmar et al.
Classical trigeminal neuralgia (TN) is a severe chronic pain disorder characterized by sudden, intense facial pain attacks and represents a major burden for affected individuals. Microvascular decompression (MVD) can provide pain relief, ye...
Low-intensity muscle contraction exercise reduces pain sensitivity by modulating peripheral pathology and spinal sensitization in end-stage knee osteoarthritis rats [0.03%]
低强度肌肉收缩运动通过调节外周病理性改变和脊髓敏化减轻膝关节骨关节炎终末期大鼠疼痛敏感性
Satoko Motokawa,Junya Sakamoto,Ryo Sasaki et al.
Satoko Motokawa et al.
Introduction: This study evaluated the effects of low-intensity muscle contraction exercise on pain sensitivity, peripheral pathology, and central sensitization in the spinal dorsal horn in a rat model of end-stage knee o...
Exploring pain and suffering through spatial acousmatic music: innovative perspectives beyond conventional music therapy [0.03%]
超越传统音乐疗法的时空声学音乐创新探索疼痛与苦难的视角
Nikos Stavropoulos,Mark I Johnson
Nikos Stavropoulos
In this perspective article we contend that acousmatic music, which departs from the traditional "instrumental music paradigm" by obscuring or removing the origin of sounds, may deepen a person's understanding and expression of pain and suf...
Expectations about pain management after discharge from total hip and knee replacement surgery: a qualitative study with patients and prescribers [0.03%]
人工髋关节和膝关节置换术后出院时的疼痛管理期望定性研究（患者和处方者视角）
Ian Liang,Peter Youssef,Abby Haynes et al.
Ian Liang et al.
Objective: This study aimed to explore the perspectives of both patients and prescribers regarding analgesia after discharge following total hip or knee replacement surgeries, focusing on opioid use and the factors influe...
NOP agonist AT-403 promoted sleep in lactic acid-induced acute pain model [0.03%]
AT-403（NOP受体激动剂）可促进乳酸诱发的急性疼痛模型中小鼠睡眠
Bethany E Pierce,Harlie A McKelvey,Mary H Hite et al.
Bethany E Pierce et al.
The majority of patients with acute pain experience sleep disturbances that persist despite analgesic treatments such as mu opioid receptor (MOP) agonists and non-steroidal anti-inflammatory drugs (NSAIDs). Further, sleep disturbances incre...
The intersection of aging, pain, and opioid use disorder: a retrospective chart review from an outpatient opioid treatment clinic [0.03%]
老年、疼痛和阿片类药物使用障碍的交集：来自门诊阿片类治疗诊所的回顾性病历审查
Bethea A Kleykamp,Hannah Smith,Erin Lynch et al.
Bethea A Kleykamp et al.
Introduction: Older adults represent a growing proportion of individuals with opioid use disorder (OUD) and adults 55 + are significantly more likely to experience a fatal overdose. This exploratory pilot study examined a...
Kelly Marie Naugle,Keela Herr
Kelly Marie Naugle