Astragalus membranaceus extract reduces functional knee joint pain: a randomized, double-blinded, placebo-controlled trial [0.03%]
膜荚黄芪提取物可减少膝关节功能疼痛：随机、双盲、安慰剂对照试验
Lorenzo Lippi,Alessio Turco,Girish H Rudrappa et al.
Lorenzo Lippi et al.
Introduction: Concerns regarding the side effects of pharmacotherapy in the management of joint pain have led to increased interest in dietary supplements. Astragalus membranaceus root extract (AME) has been proposed as a...
Dijun Wang,Ting Li,Weiqi Wang et al.
Dijun Wang et al.
Rheumatoid arthritis (RA) pain is one of the most common forms of chronic pain in clinic. A large number of RA-related literature has been reported. At present, although some analgesic measures are used in clinic, pain management after drug...
Innate immunity in chemotherapy-induced peripheral neuropathy: recent advances [0.03%]
化疗诱导的外周神经病变中的先天免疫：最近的研究进展
Nana Dong,Tongtong Lin
Nana Dong
Chemotherapy-induced peripheral neuropathy (CIPN) is a common dose-limiting side effect in patients undergoing chemotherapy. Many commonly used chemotherapeutic agents simultaneously induce neurotoxicity and modulate the immune system. Emer...
Exploring fascia in myofascial pain syndrome: an integrative model of mechanisms [0.03%]
肌筋膜痛综合征的筋膜探索：机制整合模型
Vlodeks Gromakovskis
Vlodeks Gromakovskis
Myofascial pain syndrome (MPS) is a leading cause of chronic musculoskeletal pain, yet its mechanisms remain debated. Traditional models emphasized muscle contracture or central sensitization, but growing evidence highlights fascia as a bio...
Effectiveness of medical ozone injections into the intervertebral disc on relieving lumbosacral pain-a systematic review and meta-analysis [0.03%]
医用臭氧注射治疗腰骶疼痛的疗效——系统回顾和荟萃分析
Donghui Cao,Xusheng Li,Xiao Zhang et al.
Donghui Cao et al.
Objective: To investigate the clinical efficacy of medical ozone injections into the intervertebral disc on relieving lumbosacral pain. through a systematic review and meta-analysis. ...
At the Intersection of Pain and Sleep: a Roadmap for Preclinical Pain Research [0.03%]
疼痛与睡眠的交叉口：痛症前期研究路线图
Clare M Diester,William Joo
Clare M Diester
The complex relationship between pain and sleep has received increasing attention for its therapeutic potential. Over half of chronic pain patients suffer from sleep disorders, and poor sleep is a strong predictor for pain in clinical popul...
Case Report: A case of toothache of cardiac origin with a long-term clinical course [0.03%]
心脏源性牙痛1例报告及长期随访临床表现
Chizuko Maeda,Takayuki Suga,Kiyotoshi Oishi et al.
Chizuko Maeda et al.
Background: Toothache of cardiac origin is a rare but significant form of referred pain originating from cardiac pathology such as angina pectoris. Although jaw and throat discomfort are known referred pain sites, toothac...
Acute postoperative pain trajectories and their impact on functional recovery following total knee arthroplasty [0.03%]
全膝关节置换术后急性术后疼痛病程及其对功能恢复的影响
Caijin Wen,Qin Qin,Lu Wei et al.
Caijin Wen et al.
Objective: To investigate the trajectories of acute postsurgical pain (APSP) following total knee arthroplasty (TKA), its influencing factors, and its impact on knee function recovery at 3 months postoperatively. ...
Metabolic resilience governs sex-specific pain recovery during hormonal aging: a multi-omics study of neuropathy in mice [0.03%]
代谢适应性决定激素衰老过程中神经病变小鼠的性别差异痛觉恢复：一种多组学研究
Sara Marinelli,Claudia Rossi,Luisa Pieroni et al.
Sara Marinelli et al.
Introduction: Biological aging and sex interact to shape systemic metabolism, yet their role in chronic pain resolution remains unexplored. We hypothesized that metabolic resilience-the ability to flexibly switch fuel sou...
James C Hackworth,John E Schneider,Maggie Do Valle et al.
James C Hackworth et al.
The prevalence of acute pain has grown substantially over the past two decades, due primarily to more surgeries, an aging population, and the rapid growth in the prevalence of metabolic disease. Although opioids are often the only effective...