Minimally Invasive Dentistry: Parent/Carer Perspectives on Atraumatic Restorative Treatments and Dental General Anaesthesia to the Management of Early Childhood Caries [0.03%]
微创儿童牙科治疗：家长对以儿童龋齿管理为目的的无创修复治疗和口腔全身麻醉的看法
Peter Arrow,Helen Forrest,Susan Piggott
Peter Arrow
Introduction: Parents of children treated under dental general anaesthesia (DGA) have reported feelings of concern and anxiety. This study elicited the views of parents/carers (P/C) of children with early childhood caries (ECC) who particip...
Tumor Microenvironment in Oral Cancer Following Neoadjuvant Pembrolizumab: Preliminary Analysis of the Histopathologic Findings [0.03%]
新辅助派姆单抗治疗口腔癌后的肿瘤微环境：初步病理分析结果
Alex Dobriyan,Iris Gluck,Eran Alon et al.
Alex Dobriyan et al.
Background: The tumor microenvironment (TME) of oral squamous cell carcinoma (OSCC) is associated with immune suppression, one of the pathways being the programmed death receptor 1 (PD-1) and its ligands (PD-L1/PD-L2). Checkpoint inhibitors...
Expression of Interleukin-1ß and Interleukin-8 in Oral Potentially Malignant Disorders and Carcinomas [0.03%]
口腔癌前病变和癌症中的细胞因子IL-1β和IL-8表达研究
Jeaneth Lopez-Labady,Ronell Bologna-Molina,Mariana Villarroel-Dorrego
Jeaneth Lopez-Labady
Objective: To evaluate interleukin-1ß (IL-1ß) and interleukin-8 (IL-8) epithelial expressions in potentially malignant disorders of the oral mucosa as malignant predictive markers. Study design: About 55 tissues embedded in paraffin, comp...
Oleh Andrukhov
Oleh Andrukhov
Dental mesenchymal stromal cells (MSCs) are a promising tool for clinical application in and beyond dentistry. These cells possess multilineage differentiation potential and immunomodulatory properties. Due to their localization in the oral...
At the Crossroads of Molecular Biology and Immunology: Molecular Pathways for Immunological Targeting of Head and Neck Squamous Cell Carcinoma [0.03%]
分子生物学和免疫学交叉领域：头颈鳞状细胞癌免疫治疗的分子途径
Niels E Wondergem,Dennis N L M Nijenhuis,Jos B Poell et al.
Niels E Wondergem et al.
Background: Recent advances in immunotherapy for head and neck squamous cell carcinoma (HNSCC) have led to implementation of anti-programmed death receptor 1 (PD-1) immunotherapy to standard of care for recurrent/metastatic HNSCC. However, ...
Polymorphisms in the HTR2A and HTR3A Genes Contribute to Pain in TMD Myalgia [0.03%]
HTR2A和HTR3A基因多态性对肌痛型颞下颌关节紊乱病疼痛的贡献作用
Sofia Louca Jounger,Nikolaos Christidis,Britt Hedenberg-Magnusson et al.
Sofia Louca Jounger et al.
Background: The aim of this study was to investigate if single nucleotide polymorphisms (SNPs) related to monoaminergic neurotransmission, in particular the serotonergic pathway, contribute to pain perception in patients with temporomandibu...
Inflammatory Mediators in Oral Cancer: Pathogenic Mechanisms and Diagnostic Potential [0.03%]
口腔癌的炎症介质：病理机制和诊断潜力
Sven E Niklander
Sven E Niklander
Approximately 15% of cancers are attributable to the inflammatory process, and growing evidence supports an association between oral squamous cell carcinoma (OSCC) and chronic inflammation. Different oral inflammatory conditions, such as or...
Biocultural Drivers of Salivary Microbiota in Australian Aboriginal and Torres Strait Islander Children [0.03%]
影响澳大利亚原住民儿童唾液微生物群的生物文化驱动因素
Matilda Handsley-Davis,Emily Skelly,Newell W Johnson et al.
Matilda Handsley-Davis et al.
Australian Aboriginal and Torres Strait Islander children experience unacceptably high rates of dental caries compared to their non-Indigenous Australian counterparts. Dental caries significantly impacts the quality of life of children and ...
Understanding the Matrix: The Role of Extracellular DNA in Oral Biofilms [0.03%]
理解矩阵：口腔生物膜中细胞外DNA的作用
Hannah J Serrage,Mark A Jepson,Nadia Rostami et al.
Hannah J Serrage et al.
Dental plaque is the key etiological agent in caries formation and the development of the prevalent chronic oral inflammatory disease, periodontitis. The dental plaque biofilm comprises a diverse range of microbial species encased within a ...
Combination of Clptm1L and TMEM207 Expression as a Robust Prognostic Marker in Oral Squamous Cell Carcinoma [0.03%]
Clptm1L和TMEM207联合表达作为口腔鳞状细胞癌预后标志物的风险因素分析
Kimika Hano,Kiichi Hatano,Chiemi Saigo et al.
Kimika Hano et al.
Overexpression of Cleft Lip and Palate Transmembrane 1-Like (Clptm1L) confers cancer cell survival through the endoplasmic reticulum (ER) stress survival signaling pathway, while TMEM207 impairs the tumor suppressor function of WW domain co...