Update on Disease-Modifying Pharmacological Treatments for Frontotemporal Dementia (FTD): A Scoping Review of Registered Trials [0.03%]
额叶颞叶痴呆(FTD)的疾病修饰药物治疗最新进展:注册临床试验综述
Patrick Bartoshyk,Rónán OCaoimh
Patrick Bartoshyk
Frontotemporal dementia (FTD) represents a cluster of adult-onset neurodegenerative diseases resulting from a combination of genetic and epigenetic factors. Currently, treatment is symptomatic and there are no licensed disease-modifying the...
Intraoperative Ultrasound in Brain and Spine Surgery: Current Applications, Translational Value and Future Perspectives [0.03%]
术中神经超声技术:现状、转化价值及未来展望
Carmelo Pirri,Nina Pirri,Veronica Macchi et al.
Carmelo Pirri et al.
Intraoperative ultrasound (IOUS) has developed from a rudimentary adjunct into a versatile modality that now plays a crucial role in neurosurgery. Offering real-time, radiation-free and repeatable imaging at the surgical site, it provides d...
Exploratory Behavioral Study of the Production and Processing of French Categorical Liaisons in Children with Expressive DLD [0.03%]
儿童表达性语言障碍的探索性行为研究:法语范畴连音的产生与加工
Elisabeth Cesari,Bernard Laks,Frédéric Isel
Elisabeth Cesari
Categorical liaison-defined as the obligatory pronunciation of a latent word in the form of a final consonant when followed by a vowel as the initial word or a word beginning with a silent "h" (e.g., des‿ours [dezuʁs])-is a robust phonolo...
Validation and Interpretation of the Persian Version of the Swallowing Disturbance Questionnaire in Patients with Multiple Sclerosis [0.03%]
帕金森病患者的吞咽障碍问卷的波斯语版本的有效性及解释效度研究
Omid Mirmosayyeb,Mohammad Mohammadi,Saeed Vaheb et al.
Omid Mirmosayyeb et al.
Background: Patients with multiple sclerosis (PwMS) frequently experience dysphagia, which affects their quality of life. The swallowing disturbance questionnaire (SDQ) has demonstrated potential in screening dysphagia in...
Compound Heterozygous PNKP Variants Causing Developmental and Epileptic Encephalopathy with Severe Microcephaly: Natural History of Two New Cases and Literature Review [0.03%]
PNKP复合杂合变异引起的发育性和癫痫性脑病合并严重小头畸形:2例新病例的自然史及文献回顾
Francesca Ragona,Giuliana Messina,Stefania Magri et al.
Francesca Ragona et al.
Microcephaly with early-onset, intractable seizures, and developmental delay (MCSZ) is a rare inherited neurological disorder caused by biallelic loss-of-function variants in the polynucleotide kinase/phosphatase (PNKP) gene, which encodes ...
Self-Administered Cognitive Rehabilitation Using an Electronic Device in Subacute Stroke Patients: A Proof-of-Concept Study on Safety, Feasibility, and Preliminary Efficacy [0.03%]
基于电子设备的卒中亚急性期患者自我管理认知康复的可行性、安全性和疗效概念验证研究
Cristina Fonte,Alessio Damora,Laura Abbruzzese et al.
Cristina Fonte et al.
Background: Cognitive impairment after stroke often reduces independence and quality of life. Cognitive rehabilitation is therefore essential, and recent research on computer-based interventions has shown promising result...
Neuroscience of Behavior [0.03%]
行为神经科学
Mario Treviño,Oscar Arias-Carrión,Braniff de la Torre-Valdovinos et al.
Mario Treviño et al.
Behavior is not a mere sequence of responses to stimuli but the dynamic expression of internal processes such as planning, prediction, valuation, and inference. These functions arise from distributed and metabolically costly neural systems ...
Oscar Arias-Carrión,Elizabeth Romero-Gutiérrez,Emmanuel Ortega-Robles
Oscar Arias-Carrión
Atypical parkinsonian disorders-progressive supranuclear palsy (PSP), corticobasal degeneration (CBD), and multiple system atrophy (MSA)-are rare, rapidly progressive neurodegenerative syndromes characterized by distinct molecular pathologi...
STING Signaling Deficiency Exacerbates Demyelination and Immune Infiltration in Focal EAE Lesions [0.03%]
STING信号缺陷加重 focal EAE病灶的脱髓鞘和免疫浸润
Marlene T Mørch,Line S Reinert,Anouk Benmamar-Badel et al.
Marlene T Mørch et al.
Stimulator of interferon genes (STING) is a cytosolic DNA sensor that activates type I interferon (IFN) signaling, which plays a key role in neuroinflammation. Although the role of STING in experimental autoimmune encephalomyelitis (EAE), a...
Frontal Regions and Executive Function Testing: A Doubted Association Shown by Brain-Injured Patients [0.03%]
额区和执行功能测验:脑损伤患者表现出的令人怀疑的关联性
Demis Basso,Ida Bosio,Vincenza Tarantino et al.
Demis Basso et al.
Since its introduction, the construct of executive functions (EFs) has been associated with a set of tests to assess these functions and a brain network centered in the associative frontal brain regions. While the majority of perspectives h...