Compound Heterozygous PNKP Variants Causing Developmental and Epileptic Encephalopathy with Severe Microcephaly: Natural History of Two New Cases and Literature Review [0.03%]
PNKP复合杂合变异引起的发育性和癫痫性脑病合并严重小头畸形：2例新病例的自然史及文献回顾
Francesca Ragona,Giuliana Messina,Stefania Magri et al.
Francesca Ragona et al.
Microcephaly with early-onset, intractable seizures, and developmental delay (MCSZ) is a rare inherited neurological disorder caused by biallelic loss-of-function variants in the polynucleotide kinase/phosphatase (PNKP) gene, which encodes ...
Self-Administered Cognitive Rehabilitation Using an Electronic Device in Subacute Stroke Patients: A Proof-of-Concept Study on Safety, Feasibility, and Preliminary Efficacy [0.03%]
基于电子设备的卒中亚急性期患者自我管理认知康复的可行性、安全性和疗效概念验证研究
Cristina Fonte,Alessio Damora,Laura Abbruzzese et al.
Cristina Fonte et al.
Background: Cognitive impairment after stroke often reduces independence and quality of life. Cognitive rehabilitation is therefore essential, and recent research on computer-based interventions has shown promising result...
Neuroscience of Behavior [0.03%]
行为神经科学
Mario Treviño,Oscar Arias-Carrión,Braniff de la Torre-Valdovinos et al.
Mario Treviño et al.
Behavior is not a mere sequence of responses to stimuli but the dynamic expression of internal processes such as planning, prediction, valuation, and inference. These functions arise from distributed and metabolically costly neural systems ...
Oscar Arias-Carrión,Elizabeth Romero-Gutiérrez,Emmanuel Ortega-Robles
Oscar Arias-Carrión
Atypical parkinsonian disorders-progressive supranuclear palsy (PSP), corticobasal degeneration (CBD), and multiple system atrophy (MSA)-are rare, rapidly progressive neurodegenerative syndromes characterized by distinct molecular pathologi...
STING Signaling Deficiency Exacerbates Demyelination and Immune Infiltration in Focal EAE Lesions [0.03%]
STING信号缺陷加重 focal EAE病灶的脱髓鞘和免疫浸润
Marlene T Mørch,Line S Reinert,Anouk Benmamar-Badel et al.
Marlene T Mørch et al.
Stimulator of interferon genes (STING) is a cytosolic DNA sensor that activates type I interferon (IFN) signaling, which plays a key role in neuroinflammation. Although the role of STING in experimental autoimmune encephalomyelitis (EAE), a...
Frontal Regions and Executive Function Testing: A Doubted Association Shown by Brain-Injured Patients [0.03%]
额区和执行功能测验：脑损伤患者表现出的令人怀疑的关联性
Demis Basso,Ida Bosio,Vincenza Tarantino et al.
Demis Basso et al.
Since its introduction, the construct of executive functions (EFs) has been associated with a set of tests to assess these functions and a brain network centered in the associative frontal brain regions. While the majority of perspectives h...
Enhancing Neural Efficiency in Competitive Golfers: Effects of Slow Cortical Potential Neurofeedback on Modulation of Beta Activity-An Exploratory Randomized Controlled Trial [0.03%]
提升高尔夫运动员神经效率：慢皮层电位脑反馈对β活动调制的影响——一项探索性随机对照试验
Eugenio Lizama,Luciana Lorenzon,Carolina Pereira et al.
Eugenio Lizama et al.
Background: Neural efficiency theory proposes that expert athletes optimize brain resource allocation and functioning. Beta band oscillations are associated with attention, motor preparation, and emotional control, reflec...
Effects of Telerehabilitation Platforms on Quality of Life in People with Multiple Sclerosis: A Systematic Review of Randomized Clinical Trials [0.03%]
远程康复平台对多发性硬化症患者生活质量的影响：随机临床试验的系统评价研究
Alejandro Herrera-Rojas,Andrés Moreno-Molina,Elena García-García et al.
Alejandro Herrera-Rojas et al.
Introduction: Multiple sclerosis (MS) is a chronic neurodegenerative disease that entails high costs, progressive disability, and reduced quality of life (QoL). Telerehabilitation (TR), supported by new technologies, is e...
NMDA Receptor: An Old but Refreshed Target for Neurodegeneration [0.03%]
新颖与经典并存：NMDA受体在神经退行性疾病治疗中的新机遇
Joana M Marques,Ricardo J Rodrigues
Joana M Marques
Different neurodegenerative diseases display varying etiologies and phenotypes, reflecting region-specific neurodegeneration [...].
Editorial
NeuroSci. 2025 Oct 8;6(4):102. DOI:10.3390/neurosci6040102 2025
Mitigating Head Position Bias in Perivascular Fluid Imaging: LD-ALPS, a Novel Method for DTI-ALPS Calculation [0.03%]
减轻血管周围液体成像中的头部位置偏差：一种新的DTI-ALPS计算方法（LD-ALPS）
Ford Burles,Emily Sallis,Daniel C Kopala-Sibley et al.
Ford Burles et al.
Background/objectives: The glymphatic system is a recently characterized glial-dependent waste clearance pathway in the brain, which makes use of perivascular spaces for cerebrospinal fluid exchange. Diffusion tensor imag...