The Relevance of Circadian Clocks to Stem Cell Differentiation and Cancer Progression [0.03%]
昼夜钟对干细胞分化和癌症发展的相关性研究
Astha Malik,Shreya Nalluri,Arpan De et al.
Astha Malik et al.
The molecular mechanism of circadian clocks depends on transcription-translation feedback loops (TTFLs) that have known effects on key cellular processes. However, the distinct role of circadian TTFLs in mammalian stem cells and other less ...
Localization of Thioredoxin-Interacting Protein in Aging and Alzheimer's Disease Brains [0.03%]
硫氧还蛋白相互作用蛋白在衰老和阿尔茨海默氏症大脑中的定位
Haruka Tsubaki,Anarmaa Mendsaikhan,Undral Buyandelger et al.
Haruka Tsubaki et al.
Thioredoxin-Interacting Protein (TXNIP) has been shown to have significant pathogenic roles in many human diseases, particularly those associated with diabetes and hyperglycemia. Its main mode of action is to sequester thioredoxins, resulti...
Paraskevi Sgourdou
Paraskevi Sgourdou
Deep, dreamless sleep is considered the only "normal" state under which consciousness is lost. The main reason for the voluntary, external induction of an unconscious state, via general anesthesia, is to silence the brain circuitry of nocic...
Jennifer Mather
Jennifer Mather
Temporality is one of the criteria that Birch has advanced for areas of cognitive ability that may underlie animal sentience. An ability to integrate and use information across time must be more than simply learning pieces of information an...
Marisa Cressatti,Hyman M Schipper
Marisa Cressatti
α-Synuclein is a key driver of the pathogenesis of Parkinson disease (PD). Heme oxygenase-1 (HO-1), a stress protein that catalyzes the conversion of heme to biliverdin, carbon monoxide and free ferrous iron, is elevated in PD-affected neu...
Developing the Rationale for Including Virtual Reality in Cognitive Rehabilitation and Exercise Training Approaches for Managing Cognitive Dysfunction in MS [0.03%]
开发在认知康复和运动训练方法中纳入虚拟现实以管理MS患者认知障碍的理论依据
Carly L A Wender,John DeLuca,Brian M Sandroff
Carly L A Wender
Cognitive impairment is a common and detrimental consequence of multiple sclerosis (MS) and current rehabilitation methods are insufficient. Cognitive rehabilitation (CR) and exercise training (ET) are the most promising behavioral approach...
Ultrastructural Analysis of a Forming Embryonic Embodiment in the Adult Zebrafish Optic Tectum Surviving in Organotypic Culture [0.03%]
成年斑马鱼视顶盖中正在形成的胚胎实体的组织培养中超微结构分析
Ricardo L Peguero,Nicole A Bell,Andras Bimbo-Szuhai et al.
Ricardo L Peguero et al.
It has been shown that adult zebrafish are capable of regenerating regions of the central nervous system (CNS) after insult. Unlike in higher-order vertebrates where damage to the CNS leads to glial scar formation and permanent functional d...
Remi L Landry,Monica E Embers
Remi L Landry
The potential contribution of pathogenic microbes to dementia-inducing disease is a subject of considerable importance. Alzheimer's disease (AD) is a neurocognitive disease that slowly destroys brain function, leading to cognitive decline a...
Long COVID and the Autonomic Nervous System: The Journey from Dysautonomia to Therapeutic Neuro-Modulation through the Retrospective Analysis of 152 Patients [0.03%]
长新冠与自主神经系统：152例患者回顾性分析的从自主神经失调到治疗性神经调控之路
Joseph Colombo,Michael I Weintraub,Ramona Munoz et al.
Joseph Colombo et al.
Introduction: The severity and prevalence of Post-Acute COVID-19 Sequela (PACS) or long-COVID syndrome (long COVID) should not be a surprise. Long-COVID symptoms may be explained by oxidative stress and parasympathetic an...
Bilateral Facial Palsy as the Onset of Neurosarcoidosis: A Case Report and a Revision of Literature [0.03%]
双侧面部瘫痪作为神经系统结节病首发症状的病例报道及文献复习
Chiara Gallo,Letizia Mazzini,Claudia Varrasi et al.
Chiara Gallo et al.
Unilateral facial nerve palsy (FNP) is one of the most common cranial mononeuropathies. Among rare etiologies, neurosarcoidosis (NS) can cause bilateral involvement (both recurring and simultaneous) only in 15% to 25% of cases. The rarity o...
Case Reports
NeuroSci. 2022 May 29;3(2):321-331. DOI:10.3390/neurosci3020023 2022