Cognitive Impairment in Multiple Sclerosis: An Update on Assessment and Management [0.03%]
多发性硬化症认知障碍的评估与治疗新进展
Emilio Portaccio,Maria Pia Amato
Emilio Portaccio
Cognitive impairment (CI) is a core feature of multiple sclerosis (MS) and affects up to 65% of patients in every phase of the disease, having a deep impact on all aspects of patients' lives. Cognitive functions most frequently involved inc...
Bernardo C Antunes,Tomás Mateus,Vanessa A Morais
Bernardo C Antunes
The maintenance of energetic homeostasis relies on a tight balance between glycolysis and mitochondrial oxidative phosphorylation. The case of the brain is a peculiar one, as although entailing a constant demand for energy, it is believed t...
Characterization of Anti-GAD65-Associated Neurological Syndromes: Clinical Features and Antibody Titers [0.03%]
抗GAD65相关神经综合征的特征：临床特点和抗体滴度
João Moura,Firmina Sambayeta,Ana Paula Sousa et al.
João Moura et al.
Introduction: Anti-GAD65 antibodies are associated with several neurological phenotypes. Antibody titers are increasingly recognized as useful in diagnosis and prognosis. ...
"I Wouldn't Even Know What to Ask for": Patients' and Caregivers' Experiences of Psychological Support for Huntington's Disease in Italy [0.03%]
意大利亨廷顿舞蹈病患者和护理人员接受心理支持的经历调查：“甚至不知道要求什么”
Nicolò Zarotti,Barbara D&#x;Alessio,Marta Scocchia et al.
Nicolò Zarotti et al.
People with Huntington's disease (HD) often experience psychological difficulties linked with disease progression and the adjustment to living with a chronic condition, which are also frequently shared by their informal caregivers (e.g., pa...
Frequency Domain Template Subtraction Approach to Attenuate Maternal Electrocardiogram in Fetal Electrocardiogram [0.03%]
胎儿心电图中抑制胎母心电信号的频域模板相减法研究
Susan Wang,Pooneh Roshanitabrizi,Anita Krishnan et al.
Susan Wang et al.
We develop a frequency domain template subtraction approach to attenuate the maternal ECG in the abdominal ECG measured from pregnant women. The proposed approach was tested on five public fetal ECG datasets simultaneously measured with ECG...
Effect of Enriched Environment on Cerebellum and Social Behavior of Valproic Zebrafish [0.03%]
富集环境对丙戊酸诱导的斑马鱼小脑及社交行为的影响
Bernardo Flores-Prieto,Flower Caycho-Salazar,Jorge Manzo et al.
Bernardo Flores-Prieto et al.
The etiology of autism spectrum disorder (ASD) has been linked to both genetic and epigenetic factors. Among the epigenetic factors, exposure to valproic acid (VPA), an antiepileptic and mood-modulating drug, has been shown to induce charac...
Cytotoxic Effect of Amyloid-β1-42 Oligomers on Endoplasmic Reticulum and Golgi Apparatus Arrangement in SH-SY5Y Neuroblastoma Cells [0.03%]
淀粉样蛋白-β1-42低聚体对神经母细胞瘤SH-SY5Y细胞内质网和高尔基体排列的细胞毒性作用
José J Jarero-Basulto,Yadira Gasca-Martínez,Martha C Rivera-Cervantes et al.
José J Jarero-Basulto et al.
Amyloid-β oligomers are a cytotoxic structure that is key for the establishment of the beginning stages of Alzheimer's disease (AD). These structures promote subcellular alterations that cause synaptic dysfunction, loss of cell communicati...
Influence of Temporal and Frequency Selective Patterns Combined with CSP Layers on Performance in Exoskeleton-Assisted Motor Imagery Tasks [0.03%]
时间选择性和频率选择性模式结合CSP层对外骨骼辅助运动想象任务性能的影响
Cristian David Guerrero-Mendez,Cristian Felipe Blanco-Diaz,Hamilton Rivera-Flor et al.
Cristian David Guerrero-Mendez et al.
Common Spatial Pattern (CSP) has been recognized as a standard and powerful method for the identification of Electroencephalography (EEG)-based Motor Imagery (MI) tasks when implementing brain-computer interface (BCI) systems towards the mo...
The Effect of Myofascial Stretching on Mechanical Nociception and Contributing Neural Mechanisms [0.03%]
肌肉筋膜拉伸对机械伤害感受及其神经机制的影响
Abigail W Anderson,Arthur Soncini,Kaitlyn Lyons et al.
Abigail W Anderson et al.
Myofascial stretching is often prescribed in the management of musculoskeletal pain. However, the neural mechanisms contributing to a decrease in pain are unknown. Stretching produces a sensation that may act as a conditioning stimulus in a...
Systemic Tumors Can Cause Molecular Changes in the Hippocampus That May Have an Impact on Behavior after Chronic Social Stress [0.03%]
系统肿瘤可引起海马分子变化，慢性社会压力后可能会影响行为
Olatz Goñi-Balentziaga,Alina Díez-Solinska,Garikoitz Beitia-Oyarzabal et al.
Olatz Goñi-Balentziaga et al.
Evidence indicates that chronic social stress plays a significant role in the development of cancer and depression. Although their association is recognized, the precise physiological mechanism remains unknown. In our previous work, we obse...