Sevoflurane Preconditioning Rescues PKMζ Gene Expression from Broad Hypoxia-Induced mRNA Downregulation Correlating with Improved Neuronal Recovery [0.03%]
七氟烷预处理从广泛的缺氧诱导的mRNA下调中挽救PKMζ基因表达，与改善神经元恢复相关
Joan Y Hou,Kim D Allen,A Iván Hernandez et al.
Joan Y Hou et al.
Hypoxia due to stroke is a major cause of neuronal damage, leading to loss of cognition and other brain functions. Sevoflurane preconditioning improves recovery after hypoxia. Hypoxia interferes with protein expression at the translational ...
Distinguishing Early from Late Mild Cognitive Impairment Using Magnetic Resonance Free-Water Diffusion Tensor Imaging [0.03%]
利用磁共振自由水扩散张量成像区分轻度认知障碍的早期和晚期
Maurizio Bergamino,Molly M McElvogue,Ashley M Stokes et al.
Maurizio Bergamino et al.
Mild Cognitive Impairment (MCI) is a transitional stage between normal aging and Alzheimer's disease. Differentiating early MCI (EMCI) from late MCI (LMCI) is crucial for early diagnosis and intervention. This study used free-water diffusio...
Intensive Speech Therapy for Hypokinetic Dysarthria in Parkinson's Disease: Targeting the Five Subsystems of Speech Production with Clinical and Instrumental Evaluation [0.03%]
帕金森病的密集型言语疗法：针对临床和仪器评估的五种发音子系统中的运动过弱性失语症
Annalisa Gison,Marco Ruggiero,Davide Tufarelli et al.
Annalisa Gison et al.
Background: Hypokinetic dysarthria is a speech disorder observed in almost 90% of PD patients that can appear at any stage of the disease, usually worsening as the disease progresses. Today, speech therapy intervention in PD is seen as a po...
Trends and Disparities in Parkinson's Disease Mortality in the United States with Predictions Using Machine Learning [0.03%]
美国帕金森病死亡率的变化及差距及其利用机器学习的预测结果
Henry Weresh,Kallin Hermann,Ali Al-Salahat et al.
Henry Weresh et al.
Background: Parkinson's disease (PD) is a progressive neurodegenerative condition characterized by the degradation of dopaminergic pathways in the brain. As the population in the United States continues to age, it is esse...
Neurodegenerative Disorders in Criminal Offending and Cognitive Decline Among Aging Inmates [0.03%]
神经变性障碍、犯罪行为以及老年囚犯的认知衰退
Sara Veggi,Fausto Roveta
Sara Veggi
Dementia, including Alzheimer's disease (AD) and frontotemporal dementia (FTD), presents critical challenges for correctional systems, particularly as global populations age. AD, affecting 60-80% of dementia cases, primarily impairs memory ...
Nutritional Intervention in Patients with Multiple Sclerosis, Correlation with Quality of Life and Disability-A Prospective and Quasi-Experimental Study [0.03%]
多发性硬化患者的营养干预及其与生活质量、残疾的相关性-一项前瞻性准实验研究
Konstantina Metaxouli,Chrysoula Tsiou,Eleni Dokoutsidou et al.
Konstantina Metaxouli et al.
Multiple sclerosis (MS) is a multifactorial disease, with diet and lifestyle playing an important role in its development. The Mediterranean diet has been considered to be particularly beneficial for MS patients. The aim of the present stud...
Sex Influence on Trigeminal Nerve Stimulation and Breath-Hold Diving Performance: Examination of the Autonomic Regulation of Cardiovascular Responses to Facial Cooling and Apnoea Across Sex and Varied Factors [0.03%]
性别对面神经刺激和屏息潜水表现的影响：考察自主神经系统对面部冷却和屏息时心血管反应的调节作用
Krzysztof S Malinowski,Magdalena Wszędybył-Winklewska,Paweł J Winklewski
Krzysztof S Malinowski
This review emphasises the importance of the cardiovascular response to facial cooling (FC) and breath holding in both sexes. The trigemino-cardiac reflex, triggered by FC, reduces heart rate (HR) and constricts blood vessels. When combined...
Visual Noise Mask for Human Point-Light Displays: A Coding-Free Approach [0.03%]
基于编码的无噪人点光源显示面具方法研究
Catarina Carvalho Senra,Adriana Conceição Soares Sampaio,Olivia Morgan Lapenta
Catarina Carvalho Senra
Human point-light displays consist of luminous dots representing human articulations, thus depicting actions without pictorial information. These stimuli are widely used in action recognition experiments. Because humans excel in decoding hu...
Pediatric Acute Disseminated Encephalomyelitis Triggered by Concurrent Administration of Seasonal and H1N1 Influenza Vaccines: A Case Report and Review [0.03%]
季节性和H1N1流感疫苗同时接种诱发的急性播散性脑脊髓炎1例及文献复习
George Imataka,Hideaki Shiraishi,Shigemi Yoshihara
George Imataka
Background: Acute disseminated encephalomyelitis (ADEM) is a rare, immune-mediated inflammatory disorder of the central nervous system (CNS), typically characterized by the acute onset of multifocal demyelination. The pat...
Case Reports
NeuroSci. 2024 Dec 30;6(1):1. DOI:10.3390/neurosci6010001 2024
Konstantinos Kostakos,Alexandra Pliakopanou,Vasileios Meimaridis et al.
Konstantinos Kostakos et al.
Although spatial memory has been widely studied in rodents, developmental studies involving humans are limited in number and sample size. We designed and studied the validity of two simple experimental setups for the evaluation of spatial m...