Medical Device Sterilization and Reprocessing in the Era of Multidrug-Resistant (MDR) Bacteria: Issues and Regulatory Concepts [0.03%]
多重耐药细菌时代的医疗器械灭菌和再处理：问题与监管概念
Jonathan Josephs-Spaulding,Om V Singh
Jonathan Josephs-Spaulding
The emergence of multidrug-resistant (MDR) bacteria threatens humans in various health sectors, including medical devices. Since formal classifications for medical device sterilization and disinfection were established in the 1970's, microb...
Data-Driven Prediction of Freezing of Gait Events From Stepping Data [0.03%]
基于步态数据的冻结 gait事件的数据驱动预测方法研究
Midhun Parakkal Unni,Prathyush P Menon,Lorenzo Livi et al.
Midhun Parakkal Unni et al.
Freezing of gait (FoG) is typically a symptom of advanced Parkinson's disease (PD) that negatively influences the quality of life and is often resistant to pharmacological interventions. Novel treatment options that make use of auditory or ...
Design of a Multi-Control Objective Rescue Mechanical Ventilation System (Linshomator) [0.03%]
多功能目标导向救援机械通气系统（林休莫TOR）的设计
Aritra Roy,Pushpak Singh,Simran Saha et al.
Aritra Roy et al.
In recent years, the need for a low-cost emergency ventilation system has increased unprecedentedly. Mechanical ventilation systems are widely used to cater to sudden oxygen demands, low breathing rates, and critical conditions during brady...
Modeling the Three-Dimensional Bioprinting Process of β-Sheet Self-Assembling Peptide Hydrogel Scaffolds [0.03%]
β折叠自组装肽水凝胶支架的三维生物打印过程模拟
Irene Chiesa,Cosimo Ligorio,Amedeo F Bonatti et al.
Irene Chiesa et al.
Extrusion-based three-dimensional (3D) bioprinting is nowadays the most efficient additive manufacturing technology to fabricate well-defined and clinical-scale relevant 3D scaffolds, exploiting soft biomaterials. However, trial and error a...
Harnessing Recent Advances in Synthetic DNA and Electroporation Technologies for Rapid Vaccine Development Against COVID-19 and Other Emerging Infectious Diseases [0.03%]
利用合成DNA和电穿孔技术的最新进展快速开发针对COVID-19和其他新兴传染病的疫苗
Ziyang Xu,Ami Patel,Nicholas J Tursi et al.
Ziyang Xu et al.
DNA vaccines are considered as a third-generation vaccination approach in which antigenic materials are encoded as DNA plasmids for direct in vivo production to elicit adaptive immunity. As compared to other platforms, DNA vaccination is co...
Monitoring Steam Penetration in Channeled Instruments: An Evidence-Based Worst-Case for Practical Situations [0.03%]
监控有槽器械中的蒸汽穿透情况：基于证据的实际情境最坏情况监测
Francesco Tessarolo,Michela Masè,Andrea Visonà et al.
Francesco Tessarolo et al.
Steam sterilization of channeled medical devices requires steam penetration into narrow channels. However, a quantitative characterization of this phenomenon in practical situations is lacking. This study evaluates the effect of load, loadi...
Protective Immunity to Dengue Virus Induced by DNA Vaccines Encoding Nonstructural Proteins in a Lethal Challenge Immunocompetent Mouse Model [0.03%]
登革病毒DNA疫苗编码非结构蛋白诱导免疫小鼠产生保护性免疫力
Rúbens Prince Dos Santos Alves,Robert Andreata-Santos,Carla Longo de Freitas et al.
Rúbens Prince Dos Santos Alves et al.
Dengue virus represents the main arbovirus affecting humans, but there are no effective drugs or available worldwide licensed vaccine formulations capable of conferring full protection against the infection. Experimental studies and results...
Structure-Based Modeling of SARS-CoV-2 Peptide/HLA-A02 Antigens [0.03%]
基于结构的SARS-CoV-2肽/HLA-A02抗原模型化研究
Santrupti Nerli,Nikolaos G Sgourakis
Santrupti Nerli
SARS-CoV-2-specific CD4 and CD8 T cells have been shown to be present in individuals with acute, mild, and asymptomatic Coronavirus disease (COVID-19). Toward the development of diagnostic and therapeutic tools to fight COVID-19, it is impo...
The 100 Most Influential Studies in Chimeric Antigen Receptor T-Cell: A Bibliometric Analysis [0.03%]
CAR-T细胞研究的百年千篇：哪一百篇文献影响力最大？——基于引文网络的共被引分析与多维尺度可视化研究
Beomjun Seo,Seungwook Kim,Jeeyoon Kim
Beomjun Seo
Background: Bibliometric analyses are used to provide information on trends within a specific research field, along with indicators of the impact of a publication. With such an analysis, we map the scientific landscape of chimeric antigen r...
Alicia J El Haj
Alicia J El Haj