Positive Impact of Targeted Educational Intervention in Children With Low Adherence to Growth Hormone Treatment Identified by Use of the Easypod™ Electronic Auto-injector Device [0.03%]
Easypod™电子自动注射器装置识别的生长激素治疗依从性较低的儿童中目标教育干预的积极作用
Aria Reza Assefi,Fernanda Roca,Adrián Rubstein et al.
Aria Reza Assefi et al.
Background: It is important to identify patients with low adherence to recombinant human growth hormone (r-hGH) therapy and initiate actions to improve adherence. The Merck Patient Support Program (PSP) aims to raise the awareness of these ...
A Clinical Perspective on the Role of Electronic Devices in Monitoring and Promoting Adherence in Airways Disease [0.03%]
电子设备在监测和促进呼吸系统疾病依从性中的作用的临床视角
Vincent Brennan,Christopher Mulvey,Garrett Greene et al.
Vincent Brennan et al.
Poor adherence to treatment is a common reason why patients with chronic disease have worse outcomes than might be expected. Poor treatment adherence is of particular concern among people with airways disease because, apart from not taking ...
Spectroscopic and Microscopic Approaches for Investigating the Dynamic Interactions of Anti-microbial Peptides With Membranes and Cells [0.03%]
用于研究抗菌肽与膜和细胞的动态相互作用的光谱学和显微镜方法
Andrew H A Clayton
Andrew H A Clayton
The emergence of microbes resistant to conventional antibiotics is a burgeoning threat to humanity with significant impacts on the health of people and on the health system itself. Antimicrobial peptides (AMPs) hold promise as potential fut...
Alberto Williams-Medina,Michael Deblock,Damir Janigro
Alberto Williams-Medina
Medical progress has historically depended on scientific discoveries. Until recently, science was driven by technological advancements that, once translated to the clinic, fostered new treatments and interventions. More recently, technology...
A Comparative Clinical Study of a Novel Pre-colonoscopy Bowel Capsule Preparation Against Two Commercially Available Liquid Preparations [0.03%]
一种新型胶囊式结肠镜检查清肠药与两种市售液体清肠药的临床比较研究
Harriet Kingston-Smith,Anoja W Gunaratne,John Saxon et al.
Harriet Kingston-Smith et al.
Background and Aims: Colonoscopy surveillance depends on effective bowel preparation. Inadequate bowel preparation can lead to inaccurate clinical diagnosis, insufficient visualization of the colon and increased risk of missed diagnosis. Th...
Deuterium Solid State NMR Studies of Intact Bacteria Treated With Antimicrobial Peptides [0.03%]
用抗菌肽处理完整细菌的氘固体核磁共振研究
Valerie Booth
Valerie Booth
Solid state NMR has been tremendously useful in characterizing the structure and dynamics of model membranes composed of simple lipid mixtures. Model lipid studies employing solid state NMR have included important work revealing how membran...
Digital Medication Adherence Support: Could Healthcare Providers Recommend Mobile Health Apps? [0.03%]
数字化医疗顺应性支持：医疗卫生机构能否推荐移动医疗软件？
Claudine Backes,Carla Moyano,Camille Rimaud et al.
Claudine Backes et al.
Adherence to prescribed medication is suboptimal in 50% of the chronic population, resulting in negative medical and economic outcomes. With the widespread use of mobile phones worldwide, medication adherence apps for mobile phones become p...
Revealing the Mechanisms of Synergistic Action of Two Magainin Antimicrobial Peptides [0.03%]
揭示两种magainin抗菌肽协同作用机制
Burkhard Bechinger,Dennis Wilkens Juhl,Elise Glattard et al.
Burkhard Bechinger et al.
The study of peptide-lipid and peptide-peptide interactions as well as their topology and dynamics using biophysical and structural approaches have changed our view how antimicrobial peptides work and function. It has become obvious that bo...
Exploring the Association Between Sialic Acid and SARS-CoV-2 Spike Protein Through a Molecular Dynamics-Based Approach [0.03%]
基于分子动力学的模拟方法探究SARS-CoV-2刺突蛋白与唾液酸之间的相互作用关系
Leonardo Bò,Mattia Miotto,Lorenzo Di Rienzo et al.
Leonardo Bò et al.
Recent experimental evidence demonstrated the capability of SARS-CoV-2 Spike protein to bind sialic acid molecules, which was a trait not present in SARS-CoV and could shed light on the molecular mechanism used by the virus for the cell inv...
Current Perspective: 3D Spheroid Models Utilizing Human-Based Cells for Investigating Metabolism-Dependent Drug-Induced Liver Injury [0.03%]
基于人体细胞的三维球形模型在代谢依赖型药物引起的肝损伤研究中的应用当前展望
Christopher R Cox,Stephen Lynch,Christopher Goldring et al.
Christopher R Cox et al.
Drug-induced liver injury (DILI) remains a leading cause for the withdrawal of approved drugs. This has significant financial implications for pharmaceutical companies, places increasing strain on global health services, and causes harm to ...