Mohamed Ateia,Ashley Hesterberg Butzlaff
Mohamed Ateia
Mohamed Ateia Ibrahim (environmental engineer and group leader at the US Environmental Protection Agency and adjunct assistant professor at Rice University) and Ashley Hesterberg Butzlaff (environmental engineer at the US Environmental Prot...
Maia E Czaikowski,Sophie W Anferov,John S Anderson
Maia E Czaikowski
Electrochemistry has been an increasingly useful tool for organic synthesis, as it can selectively generate reactive intermediates under mild conditions using an applied potential. Concurrently, synergistic activity of a metal and a ligand ...
Steric Modulation of CAACs Controls Orientation and Ethenolysis Performance [0.03%]
CAACs的立体调控控制着取向和乙醇性能
Katrina H Jensen,Brian W Michel
Katrina H Jensen
In this issue of Chem Catalysis, Sytniczuk, Kajetanowicz, and Grela report sterically tuned Cyclic(Alkyl)(Amino)Carbene (CAAC) ligands to protect the requisite Ru-methylidene ([Ru]=CH2) intermediate present during ethenolysis of renewable f...
Targeted Enzyme Modifications Enable Regioselective Biosynthesis of Fluorinated Polyketides [0.03%]
靶向酶修饰实现氟化聚酮类化合物的区域选择性生物合成
Sydney D Welch,Jared Cossin,Thaddeus Q Paulsel et al.
Sydney D Welch et al.
In attempts to enhance natural products as therapeutic agents, fluorination has emerged as a new tool for synthetic biologists and chemists. In recent articles published in Nature Chem. and Nature Chem. Bio., Grininger, Chang, and co-worker...
Imprinted Polymeric Nanoparticles as Artificial Enzymes for Ester Hydrolysis at Room Temperature and pH 7 [0.03%]
室温下pH值为7的酯水解的人工酶聚合成纳米粒子的印迹技术
M D Arifuzzaman,Ishani Bose,Foroogh Bahrami et al.
M D Arifuzzaman et al.
Natural esterases hydrolyze esters under physiological pHs but chemists often have to use strongly acidic or basic conditions for the same hydrolysis. We report synthetic nanoparticle catalysts that hydrolyze nonactivated alkyl esters at ro...
Selective C-H Activation of Unprotected Allylamines by Control of Catalyst Speciation [0.03%]
通过控制催化剂的物种实现未保护亚胺茋衍生物的C-H键活化
Vinod G Landge,Ankita Mishra,Waruna Thotamune et al.
Vinod G Landge et al.
An outstanding challenge in the Pd-catalyzed functionalization of allylamines is the control of stereochemistry. Terminal alkenes preferentially undergo Heck-type reactions, while internal alkenes may undergo a mixture of Heck and C-H activ...
Triazole-modified Ru-carbene complexes: A valid olefin metathesis pre-catalyst for dynamic covalent chemistry via C=C bond formation [0.03%]
通过生成C=C键用于动态共价化学的有效的 olefin metathesis 前催化剂：三唑修饰的钌卡宾配合物
Chenhuan Wang,Shuyao Zhang,Teng Yuan et al.
Chenhuan Wang et al.
The 1,2,3-triazole coordinated ruthenium carbene complexes (TA-Ru) were reported for the first time as a new class of modified Grubbs catalyst to achieve challenging olefin metathesis at higher temperatures without catalyst decomposition. P...
Nickel-Mediated Alkyl-, Acyl-, and Sulfonylcyanation of [1.1.1]Propellane [0.03%]
镍介导的[1.1.1]丙烷的氰代、酰氰代和磺酰氰代反应
Weizhe Dong,Sebastian Keess,Gary A Molander
Weizhe Dong
The replacement of traditional functional groups with polycyclic scaffolds has been increasingly rewarding in medicinal chemistry programs. Over the decades, 1,3-disubstituted bicyclo[1.1.1]pentanes (BCPs) have demonstrated the potential fo...
Photochemical iron-catalyzed decarboxylative azidation via the merger of ligand-to-metal charge transfer and radical ligand transfer catalysis [0.03%]
基于配体到金属电荷转移和自由基配体转移催化的铁光催化去羧基叠氮化反应
Shih-Chieh Kao,Kang-Jie Bian,Xiao-Wei Chen et al.
Shih-Chieh Kao et al.
Ligand-to-metal charge transfer (LMCT) using stoichiometric copper salts has recently been shown to permit decarboxylative C-N bond formation via an LMCT/radical polar crossover (RPC) mechanism; however, this method is unable to function ca...
Maia E Czaikowski,John S Anderson
Maia E Czaikowski
In this issue of Chem Catalysis, Zhang and co-workers demonstrate the utility of electrochemical methods to enable catalytic turnover, employing high-valent Cu for C-H bond fluorination with selectivity for more hydridic bonds. Correspondin...