Microcirculatory response and leukocyte activation in patients undergoing elective cardiac surgery with cardiopulmonary bypass [0.03%]
心血管外科手术患者接受心肺旁路术的微循环反应和白细胞活化状态
Emanuele Favaron,Can Ince,Ruben J Bosch et al.
Emanuele Favaron et al.
Background: Fluid administration, priming solutions, and the use of cardiopulmonary bypass (CPB) during cardiac surgery are likely to promote hemodilution and inflammatory responses, leading to microcirculatory impairment...
Efficacy and safety of remimazolam tosylate for sedation in ICU patients: A multicenter, randomized, phase 2 study [0.03%]
托硫酸盐remimazolam在ICU镇静中的疗效和安全性：一项多中心、随机的二期临床试验
Ning Liu,Fenghui Lin,Jianli Wen et al.
Ning Liu et al.
Background: Effective sedation in intensive care unit (ICU) patients is critical for minimizing agitation, ensuring safety, and facilitating mechanical ventilation. Remimazolam tosylate, a novel benzodiazepine with rapid ...
European Society of Intensive Care Medicine Clinical Practice Guideline on fluid therapy in adult critically ill patients: A path toward improved patient management [0.03%]
欧洲重症医学学会成人危重患者液体治疗临床实践指南：改善患者管理的途径
Daniel De Backer,Maurizio Cecconi,Marlies Ostermann
Daniel De Backer
Kenneth J Broadley,Alexander C Voisey,William R Ford et al.
Kenneth J Broadley et al.
Sepsis involves an unregulated response to bacterial infection, the inflammatory response leading to persistent hypotension, leading to a precipitous fall in arterial blood pressure. The major trigger for the hypotension in sepsis and septi...
Characteristics of CD4+T-cell reduction and pulmonary infections in critically ill immunocompromised patients [0.03%]
重症免疫抑制患者CD4+T细胞减少的特征及肺部感染
Yizhu Chen,Lidi Zhang,Tao Wang et al.
Yizhu Chen et al.
Background: The CD4+T-cell count is a key indicator for evaluating immunosuppression. Infections significantly influence the survival and prognosis of critically ill patients. This study aims to systematically evaluate th...
Yingyi Yang,Rui Kang,Huiting Zhou et al.
Yingyi Yang et al.
Itaconate is a mitochondrial metabolite generated from the tricarboxylic acid cycle intermediate cis-aconitate by the enzyme aconitate decarboxylase 1 (ACOD1). Beyond its metabolic role, itaconate has emerged as a critical regulator of immu...
Practice guideline on the prevention and treatment of central line-associated bloodstream infection: Part 1--Diagnosis and prevention [0.03%]
中心静脉导管相关血流感染预防与控制专家共识（上篇）——诊断和预防
Guideline working group of Chinese Society of Critical Care;Yan Kang,Xiangdong Guan,Dechang Chen
Guideline working group of Chinese Society of Critical Care;Yan Kang
Central line-associated bloodstream infection (CLABSI) is a severe complication of indwelling intravascular catheters and a leading cause of healthcare-associated infections in intensive care units (ICUs). CLABSI significantly increases mor...
Corrigendum to "Effect of timing of norepinephrine administration on prognosis of patients with septic shock: A prospective cohort study" [Journal of Intensive Medicine volume 2 (2025) 160-166] [0.03%]
“纳洛尔 administra定时使用对脓毒性休克患者预后影响：前瞻性队列研究”的勘误（第2卷，2025年，160-166页）
Yuting Li,Deyou Zhang,Hongxiang Li et al.
Yuting Li et al.
[This corrects the article DOI: 10.1016/j.jointm.2024.10.002.]. © 2025 The Authors.
Published Erratum
Journal of intensive medicine. 2025 Dec 12;6(2):196. DOI:10.1016/j.jointm.2025.11.002 2025
Cast nephropathy in the ICU: Early recognition and extracorporeal strategies to improve outcomes [0.03%]
重症监护病房中的铸型肾病：早期识别和体外策略以改善预后
Silvia De Rosa,Fiorenza Ferrari,Diana Zarantonello et al.
Silvia De Rosa et al.
Cast-induced acute kidney injury (AKI) is a frequent yet under-recognized cause of kidney dysfunction in the intensive care unit. It arises when filtered proteins or pigments - free light chains (FLCs) in multiple myeloma, myoglobin in rhab...
Electrolyte imbalance and post-open-heart surgery complications: Is there a link? [0.03%]
电解质紊乱与开胸手术后并发症的关系探讨
Uria Shaul,Pierre Singer,Ruth Mishali et al.
Uria Shaul et al.
Background: Electrolyte disturbances are common after cardiac surgery involving cardiopulmonary bypass (CPB) and may influence postoperative outcomes. Although postoperative atrial fibrillation (POAF), atelectasis, and pl...