Compliance with SEP-1 guidelines is associated with improved outcomes for septic shock but not for severe sepsis [0.03%]
SEP-1依从性与重度脓毒症不良结局无关但可改善脓毒性休克预后
Shelly N B Sloan,Nate Rodriguez,Thomas Seward et al.
Shelly N B Sloan et al.
Background: In 2018, the Centers for Medicaid and Medicare Services (CMS) issued a protocol for the treatment of sepsis. This bundle protocol, titled SEP-1 is a multicomponent 3 h and 6 h resuscitation treatment for patie...
Hongmin Zhang,Dawei Liu
Hongmin Zhang
Sepsis-induced myocardial dysfunction is common. In addition to acute coronary syndrome, at least two types of left ventricular dysfunction can occur in septic patients: typical septic cardiomyopathy (SC) and sepsis-related takotsubo cardio...
Alternatives to norepinephrine in septic shock: Which agents and when? [0.03%]
Septic休克中去甲肾上腺素的替代药物有哪些？什么时候使用？
Mathieu Jozwiak
Mathieu Jozwiak
Vasopressors are the cornerstone of hemodynamic management in patients with septic shock. Norepinephrine is currently recommended as the first-line vasopressor in these patients. In addition to norepinephrine, there are many other potent va...
Increase in chloride from baseline is independently associated with mortality in intracerebral hemorrhage patients admitted to intensive care unit: A retrospective study [0.03%]
氯离子基线变化与脑出血患者重症监护病房死亡率独立相关：一项回顾性研究
Dawei Zhou,Tong Li,Dong Zhao et al.
Dawei Zhou et al.
Background: Hyperchloremia is associated with increased mortality in critically ill patients. The objective of this study was to investigate the association between increased chloride levels and mortality outcomes in intr...
Criteria deemed important by ICU patients when designating a reference person [0.03%]
ICU患者在指定联系人时认为重要的标准
Jean-Pierre Quenot,Nicolas Meunier-Beillard,Eléa Ksiazek et al.
Jean-Pierre Quenot et al.
Background: We investigated the criteria that hospitalized patients in intensive care units (ICUs) deem important when designating relatives who are best qualified to interact with the caregiving staff. ...
Oxygenation strategy during acute respiratory failure in immunocompromised patients [0.03%]
免疫功能低下的急性呼吸衰竭患者氧合策略
Virginie Lemiale,Elise Yvin,Achille Kouatchet et al.
Virginie Lemiale et al.
Acute respiratory failure (ARF) in immunocompromised patients remains challenging to treat. A large number of case require admission to intensive care unit (ICU) where mortality remains high. Oxygenation without intubation is important in t...
Mean airway pressure has the potential to become the core pressure indicator of mechanical ventilation: Raising to the front from behind the clinical scenes [0.03%]
平均气道压有望成为机械通气的核心压力监测指标：从临床幕后走到台前
Longxiang Su,Pan Pan,Dawei Liu et al.
Longxiang Su et al.
Mean airway pressure (Pmean) is a common pressure monitoring parameter of mechanical ventilators that is closely correlated with mean alveolar pressure and represents stresses applied to the lung parenchyma during ventilation. Pmean is dete...
Ying Huang,Ruman Chen,Lai Jiang et al.
Ying Huang et al.
Sepsis-associated encephalopathy (SAE), a major cerebral complication of sepsis, occurs in 70% of patients admitted to the intensive care unit (ICU). This condition can cause serious impairment of consciousness and is associated with a high...
Oxygenation strategies after extubation of critically ill and postoperative patients [0.03%]
危重病和术后患者拔管后的氧疗策略
Arnaud W Thille,Mathilde Wairy,Sylvain Le Pape et al.
Arnaud W Thille et al.
In intensive care units (ICUs), the decision to extubate is a critical one because mortality is particularly high in case of reintubation. Around 15% of patients ready to be weaned off a ventilator experience extubation failure leading to r...
Assessment of respiratory support decision and the outcome of invasive mechanical ventilation in severe COVID-19 with ARDS [0.03%]
重症新冠肺炎相关ARDS患者的呼吸支持决策及有创机械通气预后评估
Shuhan Cai,Fangfang Zhu,Hongtao Hu et al.
Shuhan Cai et al.
Background: The coronavirus disease 2019 (COVID-19) is an ongoing pandemic. Invasive mechanical ventilation (IMV) is essential for the management of COVID-19 with acute respiratory distress syndrome (ARDS). We aimed to as...