Machine learning using the extreme gradient boosting (XGBoost) algorithm predicts 5-day delta of SOFA score at ICU admission in COVID-19 patients [0.03%]
基于极端梯度提升算法的机器学习预测COVID-19患者入住ICU时5天后的SOFA评分变化值
Jonathan Montomoli,Luca Romeo,Sara Moccia et al.
Jonathan Montomoli et al.
Background: Accurate risk stratification of critically ill patients with coronavirus disease 2019 (COVID-19) is essential for optimizing resource allocation, delivering targeted interventions, and maximizing patient survi...
High-flow nasal cannula oxygen therapy in acute hypoxemic respiratory failure and COVID-19-related respiratory failure [0.03%]
急性低氧性呼吸衰竭和COVID-19相关呼吸衰竭的高流量鼻导管吸氧治疗
Jean-Pierre Frat,Laura Marchasson,François Arrivé et al.
Jean-Pierre Frat et al.
Although standard oxygen face masks are first-line therapy for patients with acute hypoxemic respiratory failure, high-flow nasal cannula oxygen therapy has gained major popularity in intensive care units. The physiological effects of high-...
Safety and efficacy of selective RIPK1 inhibitor SIR1-365 in hospitalized patients with severe COVID-19: A multicenter, randomized, double-blind, phase 1b trial [0.03%]
选择性RIPK1抑制剂SIR1-365治疗重症COVID-19住院患者的安全性和有效性：一项多中心、随机、双盲、Ⅰb期试验
Background: Receptor-interacting protein kinase 1 (RIPK1), a serine/threonine protein kinase, is mainly activated by pro-inflammatory cytokines and pathogens, including severe acute respiratory syndrome coronavirus 2 (SAR...