A practical approach to SARS-CoV-2 testing in a pre and post-vaccination era [0.03%]
疫苗接种前后SARS-CoV-2检测的实践方法
Sean C Taylor
Sean C Taylor
As countries globally are in the process of planning, introducing or implementing mass vaccination strategies while continuing to deal with the ongoing SARS-CoV-2 pandemic, an evolution in testing strategies may be required to minimize spre...
Multi-center evaluation of Cepheid Xpert® Xpress SARS-CoV-2/Flu/RSV molecular point-of-care test [0.03%]
Cepheid XpertXpress SARS-CoV-2/Flu/RSV分子即时检测的多中心评估研究
John Sluimer,Gabriel Goderski,Sharon van den Brink et al.
John Sluimer et al.
Background: SARS-CoV-2 is taking a huge toll on society while influenza and RSV detection are also becoming more important. These viruses pose a high burden on health care. Rapid and accurate diagnostics for these pathoge...
Nasopharyngeal and serological anti SARS-CoV-2 IgG/IgA responses in COVID-19 patients [0.03%]
新型冠状病毒肺炎患者的鼻咽部和血清学抗SARS-CoV-2免疫球蛋白G/免疫球蛋白A的反应
Bernadette Crescenzo-Chaigne,Sylvie Behillil,Vincent Enouf et al.
Bernadette Crescenzo-Chaigne et al.
Background: The systemic antibody responses to SARS-CoV-2 in COVID-19 patients has been extensively studied. However, less is known about the mucosal responses in the upper airways, the site of initial SARS-CoV-2 replicat...
Audit of vaccination status of health-care workers who tested positive for SARS-CoV-2 [0.03%]
对检测出SARS-CoV-2阳性的医护人员的疫苗接种情况审计
L Berry,K Jones,T Robbins et al.
L Berry et al.
Multiple SARS-CoV-2 vaccinations have shown excellent efficacy during clinical trials. However, post vaccine surveillance is important to confirm 'real-world' findings of vaccine efficacy and safety. It is therefore imperative to identify i...
Judith Kannenberg,Carolin Schnurra,Nina Reiners et al.
Judith Kannenberg et al.
SARS-CoV-2-specific IgM antibodies wane during the first three months after infection and IgG antibody levels decline. This may limit the ability of antibody tests to identify previous SARS-CoV-2 infection at later time points. To examine i...
Single base mutations in the nucleocapsid gene of SARS-CoV-2 affects amplification efficiency of sequence variants and may lead to assay failure [0.03%]
SARS-CoV-2核衣壳基因中单碱基突变影响序列变异的扩增效率并可能导致检测失败
Nathaniel Storey,Julianne R Brown,Rui P A Pereira et al.
Nathaniel Storey et al.
Reverse transcriptase quantitative PCR (RT-qPCR) is the main diagnostic assay used to detect SARS-CoV-2 RNA in respiratory samples. RT-qPCR is performed by specifically targeting the viral genome using complementary oligonucleotides called ...
Co-infection of SARS-CoV-2 and influenza viruses: A systematic review and meta-analysis [0.03%]
SARS-CoV-2和流感病毒的共感染：系统回顾和荟萃分析
Thi Loi Dao,Van Thuan Hoang,Philippe Colson et al.
Thi Loi Dao et al.
We conducted this meta-analysis to determine the proportion of co-infection with influenza viruses in SARS-CoV-2 positive patients and to investigate the severity of COVID-19 in these patients. We included studies with SARS-CoV-2 infection ...
Lack of neutralizing activity in nonconvalescent sera, regardless of ABO blood group and anti-A isoagglutinin titer [0.03%]
不论ABO血型和抗A异凝集素滴度非恢复期血清中均缺乏中和活性
Daniele Focosi,Alfredo Rosellini,Pietro Giorgio Spezia et al.
Daniele Focosi et al.
Background: Several ABO blood groups have been associated with the likelihood of infection, severity, and/or outcome of COVID-19 in hospitalized cohorts, raising the hypothesis that anti-A isoagglutinins in non-A-group re...
Evaluation of alternative RNA extraction methods for detection of SARS-CoV-2 in nasopharyngeal samples using the recommended CDC primer-probe set [0.03%]
评估用于检测鼻咽样本中SARS-CoV-2的替代RNA提取方法（使用美国CDC推荐的一套引物和探针）
Vinícius Pietta Perez,Wallace Felipe Blohem Pessoa,Bruno Henrique Andrade Galvão et al.
Vinícius Pietta Perez et al.
Background: The efficiency of isolation and purification of the viral genome is a critical step to the accuracy and reliability of RT-qPCR to detect SARS-CoV-2. However, COVID-19 testing laboratories were overwhelmed by a...
Evaluation of the genalyte maverick SARS-CoV-2 multi-antigen serology panel [0.03%]
Genalyte Maverick SARS-CoV-2多抗原血清学检测板的评估研究
Leslie J Donato,Elitza S Theel,Nikola A Baumann et al.
Leslie J Donato et al.
Serologic testing for SARS-CoV-2 can be used for evaluation of past infection in individual patients and for community seroprevalence studies. We evaluated the analytical and clinical performance of the Genalyte Maverick SARS-CoV-2 Multi-An...