Clinical comparison and agreement of PCR, antigen, and viral culture for the diagnosis of COVID-19: Clinical Agreement Between Diagnostics for COVID19 [0.03%]
PCR、抗原和病毒培养在诊断新型冠状肺炎方面的临床比较与一致性：关于COVID19检测的一致性
Amanda Agard,Omar Elsheikh,Drew Bell et al.
Amanda Agard et al.
The aim of this study is to compare the COVID-19 nasopharyngeal PCR (NP PCR) to antigen, nasal PCR, and viral culture. One-hundred-and-fourteen risk-stratified patients were tested by culture, nasal PCR, NP PCR, and Ag testing. Twenty (48%)...
Evaluation of the artus® Prep&Amp UM RT-PCR for detection of SARS-CoV-2 from nasopharyngeal swabs without prior nucleic acid eluate extraction [0.03%]
评估适用于从鼻咽拭子样本检测SARS-CoV-2的安图斯 Prep&Amp UM RT-PCR（无需提前提取核糖核酸释放物）
Robert William O&#x;Hara,Benjamin Brown,Angela Hughes et al.
Robert William O&#x;Hara et al.
Here we describe a retrospective clinical evaluation of the QIAGEN artus® SARS-CoV-2 Prep&Amp UM RT-PCR assay that detects SARS-CoV-2 RNA without the need for a nucleic acid eluate extraction procedure. Using Roche SARS-CoV-2 RT-PCR on the...
Evaluation of the DiaSorin LIAISON SARS-CoV-2 antigen assay on nasopharyngeal swabs in two different SARS-CoV-2 pandemic waves in Switzerland: The impact of the Omicron variant on its performance [0.03%]
DiaSorin LIAISON SARS-CoV-2抗原检测试剂盒在两波新冠肺炎疫情中对鼻咽拭子标本的检测评估：奥密克戎变异株对其性能的影响
Stephanie Uster,Zana Topalli,Thomas Sasse et al.
Stephanie Uster et al.
Background: SARS-CoV-2 antigen tests reliably detect individuals with high viral loads and provide an efficient diagnostic tool to manage the current SARS-CoV-2 pandemic. However, mutations in SARS-CoV-2 variants of conce...
Sotrovimab-emergent resistance in SARS-CoV-2 Omicron: A series of three cases [0.03%]
三种情况下的新冠病毒奥密克戎株感染的sotrovimab抗性变异案例分析
Daniele Focosi,Federica Novazzi,Andreina Baj et al.
Daniele Focosi et al.
Antibody response after a booster dose of BNT162B2mRNA and inactivated COVID-19 vaccine [0.03%]
接种BNT162B2 mRNA和灭活新冠病毒疫苗后的抗体反应
Metin Yigit,Aslinur Ozkaya-Parlakay,Yasemin Cosgun et al.
Metin Yigit et al.
Introduction: The necessity of a booster dose is a matter that has not been as yet illuminated, although it is noted that neutralizing antibody titers decrease over time. We aimed therefore to evaluate antibody titers and...
Evaluation of serological assays for SARS-CoV-2 antibody testing from dried blood spots collected from cohorts with prior SARS-CoV-2 infection [0.03%]
评估SARS-CoV-2抗体检测血液斑干血斑点试验的效果：基于之前感染过SARS-CoV-2的队列人群所采集的干血斑点样本
Beth Catlett,Mitchell Starr,Dorothy A Machalek et al.
Beth Catlett et al.
Background: Dried blood spot (DBS) specimens are a useful serosurveillance tool particularly in hard-to-reach populations but their application for detecting SARS-CoV-2 infection is poorly characterised. ...
Detection of SARS-CoV-2 VOC-Omicron using commercial sample-to-answer real-time RT-PCR platforms and melting curve-based SNP assays [0.03%]
商业样本到答案的实时RT-PCR平台和熔解曲线SNP检测方法在奥密克戎变异株中的应用性能评估研究
Brian H M Sit,Kathy Hiu Laam Po,Yuk-Yam Cheung et al.
Brian H M Sit et al.
Objectives: The World Health Organization (WHO) had designated the SARS-CoV-2 lineage B.1.1.529 as the new Variant of Concern Omicron (VOC-Omicron) on 26th November 20211. Real-time reverse transcription polymerase chain ...
Use of a sample-to-result shotgun metagenomics platform for the detection and quantification of viral pathogens in paediatric immunocompromised patients [0.03%]
一项针对儿科免疫缺陷患者中病原病毒检测与定量的样本到结果鸟枪法元基因组平台的应用研究
Divya Shah,Julianne R Brown,Jack C D Lee et al.
Divya Shah et al.
Background: Infections by several DNA viruses can severely impact outcomes in paediatric immunocompromised patients. Current testing, which is generally limited to singleplex qPCR assays, can miss both common and rarer vi...
Antibodies against SARS-CoV-2 after natural infection in healthcare workers and clinical characteristics as putative antibody production prediction [0.03%]
医护人员感染SARS-CoV-2后的抗体反应及预测产生抗体的临床特征
D A T Hanssen,J Penders,K Heijgele et al.
D A T Hanssen et al.
Introduction: There is a need for detailed data on early antibody responses against SARS-CoV-2 as this may contribute to the prediction of the clinical course of COVID-19 and the optimization of convalescent plasma treatm...
From Delta to Omicron SARS-CoV-2 variant: Switch to saliva sampling for higher detection rate [0.03%]
从Delta到Omicron新冠病毒变异株：切换为唾液采样可获得更高的检出率
Margot Cornette,Bieke Decaesteker,Geert Antoine Martens et al.
Margot Cornette et al.
Background: Real-time polymerase chain reaction (RT-PCR) testing on a nasopharyngeal swab is the current standard for SARS-CoV-2 virus detection. Since collection of this sample type is experienced uncomfortable by patien...