Herbal medications and natural products for patients with covid-19 and diabetes mellitus: Potentials and challenges [0.03%]
冠状病毒病与糖尿病患者的草药及天然药物治疗：机遇和挑战
Abdurrahman Pharmacy Yusuf,Jian-Ye Zhang,Jing-Quan Li et al.
Abdurrahman Pharmacy Yusuf et al.
Background: The presence of diabetes mellitus (DM) among COVID-19 patients is associated with increased hospitalization, morbidity, and mortality. Evidence has shown that hyperglycemia potentiates SARS-CoV-2 (severe acute...
Molecular and structural insights of β-boswellic acid and glycyrrhizic acid as potent SARS-CoV-2 Envelope protein inhibitors [0.03%]
β-乳香酸和甘草酸作为强效SARS-CoV-2包膜蛋白抑制剂的分子及结构见解
Syeda Warisul Fatima,Shahenvaz Alam,Sunil K Khare
Syeda Warisul Fatima
Background: Over million people have been infected with SARS-CoV-2 virus worldwide, with around 3% reported deaths till date. A few conventional antiviral treatments have been tried to mitigate the coronavirus. However, m...
In silico, in vitro screening of plant extracts for anti-SARS-CoV-2 activity and evaluation of their acute and sub-acute toxicity [0.03%]
基于计算和体外筛选植物提取物的抗SARS-CoV-2活性及对其急性亚急性毒性的评估研究论文摘要
Damle Latha,Damle Hrishikesh,Ganju Shiban et al.
Damle Latha et al.
Background: In the absence of a specific drug for COVID 19, treatment with plant extracts could be an option worthy of further investigation and has motivated to evaluate the safety and anti-SARS-CoV-2 activity of plant e...
Effects of theaflavin-gallate in-silico binding with different proteins of SARS-CoV-2 and host inflammation and vasoregulations referring an experimental rat-lung injury [0.03%]
茶黄素加棓与SARS-CoV-2不同蛋白及宿主炎症和血管调节的体内结合效果并参考实验性肺损伤的大鼠模型结果
Smarajit Maiti,Amrita Banerjee,Mehak Kanwar
Smarajit Maiti
Background SARS-CoV-2 claimed 5,209,104 lives, infected 260,997,910 individuals, globally. Infection is caused due to exposure or susceptibility; deaths occur due to age,comorbidity,higher-viral-load, immuno-suppression, inflammation, and m...
Research on the mechanism of berberine in the treatment of COVID-19 pneumonia pulmonary fibrosis using network pharmacology and molecular docking [0.03%]
网络药理学和分子对接技术在探究小檗碱治疗新型冠状病毒肺炎肺纤维化机制中的研究
Junfeng Cao,Lianglei Li,Li Xiong et al.
Junfeng Cao et al.
Purpose Pulmonary fibrosis caused by COVID-19 pneumonia is a serious complication of COVID-19 infection, there is a lack of effective treatment methods clinically. This article explored the mechanism of action of berberine in the treatment ...
Revisiting liquorice (Glycyrrhiza glabra L.) as anti-inflammatory, antivirals and immunomodulators: Potential pharmacological applications with mechanistic insight [0.03%]
从抗炎、抗病毒和免疫调节角度重新审视甘草(Glycyrrhiza glabra L。)的药用价值：具有机制见解的潜在药理应用
Dheeraj Bisht,Mohmmad Rashid,Rajeshwar Kamal Kant Arya et al.
Dheeraj Bisht et al.
Background: Glycyrrhiza glabra L. (G. glabra) commonly known as liquorice is one of the highly exploited and utilized medicinal plant of the world. Since ancient times liquorice is considered as an auspicious and valuable...
Axelle Septembre-Malaterre,Ahcène Boumendjel,Anne-Laure Sandenon Seteyen et al.
Axelle Septembre-Malaterre et al.
Background: Polyphenols and particularly flavonoids are of constant interest to the scientific community. Flavonoids are investigated for their biological and pharmacological purposes, notably as antioxidant, anticancer, ...
Phytoconstituents from ten natural herbs as potent inhibitors of main protease enzyme of SARS-COV-2: In silico study [0.03%]
基于计算研究的十种天然草药植物有效成分作为SARS-CoV-2主要蛋白酶抑制剂的研究
Nitish Kumar,Atamjit Singh,Harmandeep Kaur Gulati et al.
Nitish Kumar et al.
Background: Lack of treatment of novel Coronavirus disease led to the search of specific antivirals that are capable to inhibit the replication of the virus. The plant kingdom has demonstrated to be an important source of...
Computational screening of phytochemicals from three medicinal plants as inhibitors of transmembrane protease serine 2 implicated in SARS-CoV-2 infection [0.03%]
计算筛选三种药用植物中的植物化学成分作为SARS-CoV-2感染的跨膜丝氨酸蛋白酶2抑制剂
Omotayo O Oyedara,Joseph M Agbedahunsi,Folasade M Adeyemi et al.
Omotayo O Oyedara et al.
Background: SARS-CoV-2 infection or COVID-19 is a major global public health issue that requires urgent attention in terms of drug development. Transmembrane Protease Serine 2 (TMPRSS2) is a good drug target against SARS-...
The potential of BEN815 as an anti-inflammatory, antiviral and antioxidant agent for the treatment of COVID-19 [0.03%]
BEN815用作治疗新冠肺炎的抗炎、抗病毒和抗氧化剂的潜力
Jin A Shin,Subin Oh,Jong-Moon Jeong
Jin A Shin
Background: The corona virus disease 2019 (COVID-19) pandemic has highlighted the fact that there are few effective antiviral agents for treating severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections. Al...