Identification and expression analysis of IL-2 receptors in large yellow croaker (Larimichthys crocea) [0.03%]
大黄鱼(Larimichthys crocea)中白细胞介素-2受体的鉴定及表达分析
Pengfei Mu,Jieying Huo,Min Sun et al.
Pengfei Mu et al.
Interleukin-2 (IL-2) signals influence various lymphocyte subsets during differentiation, immune responses and homeostasis. IL-2 acts on different cells by binding to its receptors (IL-2R), which consists of three subunits, IL-2Rα (CD25), ...
NLRP3-like protein negatively regulates the expression of antimicrobial peptides in Penaeus vannamei hemocyates [0.03%]
NLRP3样蛋白负调控凡纳滨对虾血细胞的抗菌肽表达
Zhihong Zheng,Deyi Tang,Weiling Zhao et al.
Zhihong Zheng et al.
NACHT, LRR and PYD domains-containing protein 3 (NLRP3) protein is the core actor involved in inflammasome formation, and plays a pivotal role in the innate immune response. However, whether NLRP3 participates in the regulation of innate im...
Rapid regulation of hemocyte homeostasis in crayfish and its manipulation by viral infection [0.03%]
病毒传染对 crayfish血细胞稳态的快速调节及其操控
Zaichao Zheng,Fang Li,Hongyu Li et al.
Zaichao Zheng et al.
In crustaceans, the number of circulating hemocytes changes rapidly in response to pathogen infection and injury, but the underlying mechanism remains unclear. In this study, we investigated the regulation of hemocytes homeostasis in crayfi...
Characterization and functional analysis of hybrid pearl gentian grouper (Epinephelus lanceolatus♂ × Epinephelus fuscoguttatus♀) complement C3 against Cryptocaryon irritans infection [0.03%]
杂交珍珠石斑鱼(Epinephelus lanceolatus ♂×Epinephelus fuscoguttatus ♀)补体C3对Cryptocaryon irritans感染的特征和功能分析
Zequan Mo,Biao Jiang,Xueli Lai et al.
Zequan Mo et al.
Pearl gentian grouper is a new aquacultural hybrid resulted from breeding of female tiger grouper (Epinephelus fuscogutattus) and male giant grouper (E. lanceolatus). Our preliminary study found that pearl gentian grouper exhibits less susc...
Characterization and functional analysis of tandem threonine containing C-type lectin (Thr-Lec) from the ridgetail white prawn Exopalaemon carinicauda [0.03%]
脊尾白对虾串联苏氨酸C-型凝集素(Thr-Lec)的特征和功能分析
Xin Huang,Guanjie Li,Beixiang Liu et al.
Xin Huang et al.
As an important pattern-recognition receptor (PRR), C-type lectins (CTLs) play significant roles in recognizing microbes and battle against pathogenic microorganism in innate immunity. In this study, two tandem threonine containing CTLs (de...
Functional role of CD40 and CD154 costimulatory signals in IgZ-mediated immunity against bacterial infection [0.03%]
CD40和CD154共刺激信号在抵抗细菌感染的IgZ介导免疫中的功能作用
Ning Su,Chong-Bin Hu,Tong Shao et al.
Ning Su et al.
CD40 and CD154 are one of the best-characterized costimulatory molecules essential for adaptive immunity, which extensively involved in T and B cell activation, IgM Ab production, isotype class switching, germinal center formation and affin...
Identification and expression of phospholipase A2 genes related to transcriptional control in the interleukin-17A/F1 pathway in the intestines of Japanese medaka Oryzias latipes [0.03%]
日本青鳉鱼肠道白细胞介素17A/F1通路中与转录控制相关的磷脂酶A2基因的识别和表达
Yo Okamura,Hiroshi Miyanishi,Tomoya Kono et al.
Yo Okamura et al.
Phospholipase A2 (PLA2), a phospholipid hydrolase, has recently attracted attention owing to its broad functionality. Immunological evidence has revealed increased susceptibility to infectious diseases and immunodeficiency in knockout (KO) ...
Essential role of 4E-BP1 for lymphocyte activation and proliferation in the adaptive immune response of Nile tilapia [0.03%]
尼罗河鲈适应性免疫反应中淋巴细胞激活和增殖中4E-BP1的重要作用
Cheng Li,Kang Li,Kunming Li et al.
Cheng Li et al.
Eukaryotic translation initiation factor 4E-binding protein 1 (4E-BP1) is a translation repressor downstream of mTORC1 pathway, and plays a pivotal role in the adaptive immune response. However, whether 4E-BP1 participates in the regulation...
Effect of parenteral endotoxin administration on the immuno-haematological responses of catfish , Heteropneustes fossilis [0.03%]
外源内毒素对鲶鱼(Heteropneustes fossilis)免疫血液反应的影响
S K Nayak,N Jahan,S Pattnaik
S K Nayak
Endotoxin, the outer cell wall membrane lipopolysaccharide component of the Gram-negative bacteria is a factor responsible for a number of complications/disorders and plays important role in the associated with pathophysiological complicati...
Long-term dexamethasone treatment increases the engraftment efficiency of human breast cancer cells in adult zebrafish [0.03%]
长期的DEX治疗提高了成人斑马鱼移值人类乳腺癌细胞的效率
Juliana Moreira Mendonça-Gomes,Thalita Marcolan Valverde,Thaís Maria da Mata Martins et al.
Juliana Moreira Mendonça-Gomes et al.
The host immune system tends to reject xenogenic-implanted cells making tumor development in adult host animal models difficult. Immune system suppression is used for successful xenotransplantation of human cancer cells in many animal model...