Autonomous cryoprotectant loading of the oocyte using microfluidic transistors [0.03%]
使用微流体晶体管进行卵母细胞自动冷冻保护剂装载
Li Zhan,Hunter Hinnen,Kaustav A Gopinathan et al.
Li Zhan et al.
Oocyte cryopreservation is a critical step of in vitro fertilization (IVF). The handling and loading of cryoprotectant currently rely on manual pipetting methods, which leads to outcome variations, high cost and limited accessibility. Here ...
A soft robotic, modular laparoscopic grasper for atraumatic retraction of the small intestine [0.03%]
一种软体模块化腹腔镜夹持器 用于小肠无创伤牵拉
Lorenzo Kinnicutt,Leah T Gaeta,Jacob Rogatinsky et al.
Lorenzo Kinnicutt et al.
In order to address the risk of iatrogenic trauma and retraction challenges associated with minimally invasive surgery, we propose a novel laparoscopic grasper equipped with a suction unit and elastomeric actuators that are inherently soft ...
Bioelectronic Drug-free Control of Opportunistic Pathogens through Selective Excitability [0.03%]
通过选择性兴奋无药物控制机会性病原体的生物电子药物
Saehyun Kim,Ethan Eig,Jiping Yue et al.
Saehyun Kim et al.
The natural excitability in mammalian tissues has been extensively exploited for drug-free electroceutical therapies. However, it is unclear whether bacterial residents on the human body are equally excitable and if their excitability can a...
Wearable bioelectronics based on emerging nanomaterials for telehealth applications [0.03%]
基于新兴纳米材料的远程医疗应用可穿戴生物电子设备
Yichong Ren,Feng Zhang,Zheng Yan et al.
Yichong Ren et al.
Nanomaterial-driven, soft wearable bioelectronics are transforming telemedicine by offering skin comfort, biocompatibility, and the capability for continuous remote monitoring of physiological signals. The devices, enabled by advanced zero-...
Leah T Gaeta,M Deniz Albayrak,Lorenzo Kinnicutt et al.
Leah T Gaeta et al.
For individuals with hand motor function losses, rehabilitation is necessary for regaining strength and range of motion to accomplish daily activities. Typically within a clinical setting, repetitive strength-based and task-specific exercis...
Hen-Wei Huang,Peter R Chai,Seungho Lee et al.
Hen-Wei Huang et al.
Naloxone can effectively rescue victims from opioid overdose, but less than 5% survive due to delayed or absent first responder intervention. Current overdose reversal systems face key limitations, including low user adherence, false positi...
Experimental Full-volume Airway Approximation for Assessing Breath-dependent Regional Aerosol Deposition [0.03%]
一种实验性全气道逼近法用于评估呼吸依赖性的局部气溶胶沉降分布规律
Ian R Woodward,Yinkui Yu,Catherine A Fromen
Ian R Woodward
Modeling aerosol dynamics in the airways is challenging, and most modern personalized in vitro tools consider only a single inhalation maneuver through less than 10% of the total lung volume. Here, we present an in vitro modeling pipeline t...
Arincheyan Gerald,Kamin Palkawong Na Ayuddhaya,Max McCandless et al.
Arincheyan Gerald et al.
Colonoscopies are vital procedures allowing diagnosis of colorectal cancer and other gastrointestinal diseases. However, excessive forces may be applied to the colon during navigation. This can cause bleeding, especially in patients present...
Design of an injectable, self-adhesive, and highly stable hydrogel electrode for sleep recording [0.03%]
一种用于睡眠记录的可注射、自粘附和高度稳定的水凝胶电极的设计
Ju-Chun Hsieh,Weilong He,Dhivya Venkatraghavan et al.
Ju-Chun Hsieh et al.
High-quality and continuous electroencephalogram (EEG) monitoring is desirable for sleep research, sleep monitoring, and the evaluation and treatment of sleep disorders. Existing continuous EEG monitoring technologies suffer from fragile co...
Transparent and Conformal Microcoil Arrays for Spatially Selective Neuronal Activation [0.03%]
用于空间选择性神经元激活的透明且符合形状的微线圈阵列
Vineeth Raghuram,Aditya D Datye,Shelley I Fried et al.
Vineeth Raghuram et al.
Micromagnetic stimulation (μMS) using small, implantable microcoils is a promising method for achieving neuronal activation with high spatial resolution and low toxicity. Herein, we report a microcoil array for localized activation of cort...