Deep Learning-Based Quantification of Vitreous Hyperreflective Foci as a Biomarker for Intraocular Inflammation [0.03%]
基于深度学习的玻璃体内高反射焦点量化作为眼内炎症生物标志物的方法
Yaniv Cohen,Maxime Usdin,Matthew McLeod et al.
Yaniv Cohen et al.
Objective: To develop and validate an artificial intelligence (AI)-driven pipeline to quantify vitreous hyperreflective foci (vHRF) from OCT images and assess their association with intraocular inflammation (IOI). ...
Altered Spontaneous Brain Activity in Adolescents and Adults with Comitant Strabismus and Strabismic Amblyopia [0.03%]
斜视和斜视性弱视青少年和成人异常的自发脑活动
Yiru Huang,Zitian Liu,Yanyan Wu et al.
Yiru Huang et al.
Purpose: Neuroimaging studies have established that strabismus and amblyopia are associated with structural and functional brain alterations. However, differences in spontaneous brain activity between strabismus patients ...
Artificial Intelligence-Driven Multimodal Prediction of 10-Year Incident Glaucoma Integrating Genetic and Deep Learning-Derived Imaging Features [0.03%]
基于遗传和深度学习派生的图像特征的多模态人工智能驱动的10年期新发青光眼预测模型
Fengze Wu,Xiaoyi Raymond Gao
Fengze Wu
Purpose: Glaucoma is the leading cause of irreversible blindness worldwide. It often remains asymptomatic until advanced stages. Hence, accurate prediction of glaucoma is crucial for timely intervention to prevent vision ...
Rapid Access Macular Screening and Evaluation: A Datasheet for a Dataset to Diagnose and Triage Macular Diseases [0.03%]
快速黄斑筛查和评估：一个用于诊断和分类黄斑疾病的数据集资料表
Ariel Yuhan Ong,Reena Chopra,Henry David Jeffry Hogg et al.
Ariel Yuhan Ong et al.
Purpose: Macular disease can cause significant visual morbidity. Timely and accurate diagnosis and management is paramount. However, there is a lack of high-quality multimodal datasets reflective of real-world clinical pr...
Deep Learning-Guided Retinal Vascular Morphometric Quantification in Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy Mouse Models [0.03%]
基于深度学习的CADASIL小鼠模型视网膜血管形态定量分析方法
Hyungwoo Lee,Na-Kyung Ryoo,Said Arevalo-Alquichire et al.
Hyungwoo Lee et al.
Purpose: To develop and validate an explainable deep learning-guided workflow to localize and quantify focal retinal luminal pathology on fundus fluorescein angiography (FFA) in NOTCH3 variant knock-in mouse models of cer...
Low Rates of Fibrosis in Eyes Treated with the Port Delivery Platform with Ranibizumab or with Monthly Ranibizumab in the Archway Trial [0.03%]
Archway研究中Port Delivery系统注射雷珠单抗或每月注射雷珠单抗眼的低纤维化发生率
Usha Chakravarthy,Chui Ming Gemmy Cheung,Giovanni Staurenghi et al.
Usha Chakravarthy et al.
Purpose: To evaluate the proportion of eyes with fibrosis in the Archway neovascular age-related macular degeneration trial, which compared efficacy and safety between monthly injections of ranibizumab with treatment via ...
Integrative Network Pharmacology Analysis of Gut Microbial Metabolite-Mediated Gut-Eye Axis Regulation in Major Blinding Retinal Diseases [0.03%]
基于整合网络药理学分析的主要致盲性视网膜疾病中的肠道微生物代谢物介导的肠-眼轴调控机制研究
Bin Wei,Jingfen Zhang,Yichong Duan et al.
Bin Wei et al.
Objective: To systematically investigate the shared and disease-specific mechanisms by which gut microbial metabolites may regulate age-related macular degeneration (AMD), diabetic retinopathy (DR), and retinal vein occlu...
Evaluation of Hyaloid Artery Persistence as a Biomarker in Retinopathy of Prematurity Using OCT [0.03%]
采用OCT评估玻璃体血管持续存在作为早产儿视网膜病变的生物标志物的效果
Hanna N Luong,Aaron S Coyner,Elizabeth V Roti et al.
Hanna N Luong et al.
Objective: To evaluate whether hyaloid artery persistence, detected by handheld OCT, is associated with retinopathy of prematurity (ROP) severity. Design:...
Clinical and Molecular Features of CNGA1-Associated Retinitis Pigmentosa in an East Asian Cohort: Insights for Gene Therapy Trials [0.03%]
CNGA1相关视网膜色素变性临床及分子特征的东亚人群研究：基因治疗研究新见解
Zishi Liu,Jae Shin Song,Jieqiong Chen et al.
Zishi Liu et al.
Purpose: To characterize the natural history of CNGA1-associated retinitis pigmentosa (RP) in an East Asian cohort and to identify potential endpoints for clinical trials. ...