Central and Peripheral Alterations of Retinal and Choroidal Vasculature in Multiple Sclerosis: Insights from Multimodal Imaging [0.03%]
多发性硬化症视网膜和脉络膜血管中枢和外周改变的见解来自多模式成像
Jamie Mitchell,Gemma McIlwaine,Emma Pead et al.
Jamie Mitchell et al.
Purpose: To evaluate retinal and choroidal vascular alterations in multiple sclerosis (MS) using multimodal imaging and determine their association with disability and disease progression. ...
Geographic Atrophy in Patients with Age-Related Macular Degeneration Is Associated with Rare Variants in Complement Factor H and Complement Factor I [0.03%]
年龄相关性黄斑变性患者中地圖样萎缩与补体因子H和补体因子I罕见变异有关
Anita de Breuk,Sarah de Jong,Bjorn Bakker et al.
Anita de Breuk et al.
Purpose: To describe the phenotype of patients with age-related macular degeneration (AMD) carrying rare genetic variants in the complement factor H (CFH) and complement factor I (CFI) genes. ...
Fluid Volumes Longitudinal Modeling to Predict Atrophy and Fibrosis in Neovascular Age-Related Macular Degeneration [0.03%]
基于液体体积纵向评估预测新生血管性年龄相关性黄斑变性的萎缩和纤维化
Stefano Mercuri,Stefan Sacu,Sophie Frank-Publig et al.
Stefano Mercuri et al.
Purpose: To evaluate the impact of retinal fluid volumes on the development of atrophy and fibrosis in neovascular age-related macular degeneration (nAMD) during routine care. ...
Prospective Data Curation Enables High-Performance Artificial Intelligence for Diabetic Retinopathy Screening in a Resource-Limited Setting [0.03%]
前瞻性数据整理可让糖尿病视网膜病变筛查人工智能在资源缺乏地区高效运行
Cameron M Ashrafzadeh,Milan Bahi,Amira Mostafa et al.
Cameron M Ashrafzadeh et al.
Purpose: To determine whether a high-quality, prospectively curated dataset can, by itself, enable the development of robust and clinically effective artificial intelligence as a medical device (AIaMD) models for diabetic...
Applying Lincoff's Rule to Central Serous Chorioretinopathy: The Macula Society International CSCR Research Network (MICRoN) Report-15 [0.03%]
Lincoff法则在中央性浆液性脉络膜视网膜病变中应用的有效性——Macula Society国际CSCCN研究网络（MICRoN）第15号报告
Niroj Kumar Sahoo,Giulia Gregori,Nasiq Hasan et al.
Niroj Kumar Sahoo et al.
Purpose: To characterize subretinal fluid (SRF) accumulation patterns in central serous chorioretinopathy (CSCR) and develop a nonangiographic approach for predicting leak location, applying principles similar to Lincoff'...
Novel Clinical Trial Designs for Intermediate Age-Related Macular Degeneration [0.03%]
老年黄斑变性中期临床试验的新设计方法研究
Alessandro Berni,Mengxi Shen,Jeremy Liu et al.
Alessandro Berni et al.
Purpose: To develop and model clinical trial designs for intermediate age-related macular degeneration (iAMD) using OCT-based structural biomarkers to define inclusion criteria and estimate sample size requirements for de...
Safety and Biodistribution of Topical Laquinimod, an Immunomodulator Targeting Aryl Hydrocarbon Receptor: The LION Study [0.03%]
关于免疫调节剂拉奎尼莫的局部用药安全性和组织分布的LION研究（英文简称：狮子研究）
Dalia El Feky,Amir Akhavanrezayat,Azadeh Mobasserian et al.
Dalia El Feky et al.
Purpose: To evaluate the safety, tolerability, and distribution of laquinimod (LAQ) eye drops as a potential steroid-sparing anti-inflammatory therapy. De...
First-in-Human Clinical Evaluation of a Novel Nonsurgical Suprachoroidal Delivery Approach for Triamcinolone in Diabetic Macular Edema [0.03%]
人源化临床评估新型非手术后葡萄膜腔注射三氯叔丁醇治疗糖尿病黄斑水肿
Yoreh Barak,Alexey Rapoport,Keren Mano-Tamir et al.
Yoreh Barak et al.
Purpose: To evaluate the safety, tolerability, and effectiveness of the Everads Injector, a novel suprachoroidal drug delivery device, for administration of triamcinolone acetonide (TA) in patients with diabetic macular e...
Association of Autosomal Dominant Snowflake Vitreoretinal Degeneration with Retinoschisis [0.03%]
常染色体显性遗传雪花状视网膜变性与视网膜劈裂症的关系分析
Bikash R Pattnaik,Ken K Nischal,Oleg Alekseev et al.
Bikash R Pattnaik et al.
Objective: To define and characterize the clinical association of autosomal dominant snowflake vitreoretinal degeneration (SVD) with retinochisis arising from a heterozygous KCNJ13 variant in unrelated multigenerational f...
Plasma Metabolomic Associations with Incident Rhegmatogenous Retinal Detachment in UK Biobank [0.03%]
英国生物样本库中代谢组与视网膜裂孔的关系
Yuelan Gao,Jianming Xu,Jun Yu et al.
Yuelan Gao et al.
Objective: To investigate the associations of plasma metabolites with incident rhegmatogenous retinal detachment (RRD). Design: A prosp...