A geroscience response to cancellation of the UK's Medicines Repurposing Programme: challenges and opportunities [0.03%]
英国医药再定位计划取消事件的衰老科学应对方案:挑战与机遇响应文章
Nicholas J W Rattray,Zahra Rattray,Ilaria Bellantuono et al.
Nicholas J W Rattray et al.
The Lancet Healthy Longevity
The Lancet Healthy Longevity
Esther K Hui,Andrew Sommerlad,Hamish Naismith
Esther K Hui
Imaging biomarkers of ageing: a review of artificial intelligence-based approaches for age estimation [0.03%]
基于人工智能的年龄估测成像生物标志物的研究进展综述
Fridolin Haugg,Grace Lee,John He et al.
Fridolin Haugg et al.
Chronological age, although commonly used in clinical practice, fails to capture individual variations in rates of ageing and physiological decline. Recent advances in artificial intelligence (AI) have transformed the estimation of biologic...
Associations between life course exposure to ambient air pollution with cognition and later-life brain structure: a population-based study of the 1946 British Birth Cohort [0.03%]
基于1946年英国出生队列的前瞻性研究:生命历程接触大气污染与认知及晚年内在脑结构之间的关联性分析
Thomas Canning,Jorge Arias-de la Torre,Helen L Fisher et al.
Thomas Canning et al.
Background: Previous research has linked higher exposure to air pollution to increased cognitive impairment at older ages. We aimed to extend the existing evidence in this area by incorporating exposures across the life c...
Method-specific suicide mortality rates among older adults in 47 countries and territories, 1996-2021, with projections to 2050: a global time series and modelling study [0.03%]
47个国家和地区1996年至2021年的老年人自杀死亡率(按方法分类)及其2050年预测值:全球时间序列和建模研究
Hanseul Cho,Soeun Kim,Yejun Son et al.
Hanseul Cho et al.
Background: Suicide rates are highest among older adults, yet comprehensive global studies are limited. This study aimed to estimate suicide mortality rates among older adults aged 65 years and older across 47 countries a...
Factors related to blood-based biomarkers for neurodegenerative diseases and their intergenerational associations in the Young Finns Study: a cohort study [0.03%]
青年芬兰研究中与神经退行性疾病的血液生物标志物及其代际关联相关的因素:群组队列研究
Marja A Heiskanen,Juha Mykkänen,Katja Pahkala et al.
Marja A Heiskanen et al.
Background: Blood-based biomarkers (BBM) of neurodegenerative diseases are emerging as cost-effective tools in the differential diagnostics of Alzheimer's disease and other dementias. Scarce data exist about factors expla...
Influence of age on the association of vascular risk factors with acute stroke (INTERSTROKE): a case-control study [0.03%]
年龄对血管危险因素与急性卒中之间关联的影响( INTERSTROKE):一项病例对照研究
Catriona Reddin,Graeme J Hankey,John Ferguson et al.
Catriona Reddin et al.
Background: The absolute burden of stroke is increasing due to an ageing population, as well as an increased incidence of stroke in young adults. We aimed to determine whether age modifies the magnitude of association bet...
Is pneumococcal vaccination required for new residents of care facilities for older adults? [0.03%]
新的养老院入住者需要肺炎球菌疫苗接种吗?
Claire von Mollendorf
Claire von Mollendorf
Pneumococcal vaccination for new residents entering older adult care homes in England: national observational surveillance study [0.03%]
英格兰养老院新入住老人肺炎球菌疫苗接种的国家观察性监测研究
Fariyo Abdullahi,Tara Patel,Kelly Stoker et al.
Fariyo Abdullahi et al.
Background: The incidence of invasive pneumococcal disease (IPD) increases rapidly with age. In the UK, adults aged 65 years are eligible for the 23-valent pneumococcal polysaccharide vaccine (PPV23) as part of the nation...