A genomic compendium of hundreds of teleost fishes reveals their evolutionary landscape [0.03%]
鱼类基因组综述揭示其进化景观
Yue Song,Zengbao Yuan,Chengchi Fang et al.
Yue Song et al.
The remarkable morphological diversity and species abundance of teleost fishes offer a valuable resource for understanding vertebrate evolution. In phase I of the Fish10K project, genomes of 110 teleost species were sequenced and assembled,...
Leveraging biomarkers and primary care embedding for scalable precision cancer prevention in China: Insights from the FuSion study [0.03%]
中国精准癌症预防生物标志物和基层医疗嵌入的可扩展性研究:来自FuSion研究的启示
Huangbo Yuan,Yanfeng Jiang,Zhenqiu Liu et al.
Huangbo Yuan et al.
Hydrogel-mEV-SKAP2: A promising biotherapeutic product for male fertility decline [0.03%]
新型生物疗法产品Hydrogel-mEV-SKAP2有望治疗男性不育症
Guanghui Zhang,Kuan Sun,Jiaming Zhou et al.
Guanghui Zhang et al.
mRNA-engineered CRISPR-Cas epigenetic editors enable durable and efficient gene silencing in vivo [0.03%]
工程化的mRNA CRISPR-Cas表观遗传编辑系统可在体内实现高效和持久的基因沉默功能
Chao Xu,Chen Zeng,Mengge Wang et al.
Chao Xu et al.
Programmable epigenetic editors (EEs) that achieve long-term gene expression modulation without altering the DNA sequence hold immense therapeutic potential. However, the clinical translation of current CRISPR-based epigenome editors is imp...
Insights into knowledge evolution based on semantic representation and dynamic visual analytics [0.03%]
基于语义表示和动态视觉分析的知识进化洞察力
Jieyang Peng,Jianing Li,Zhibin Niu et al.
Jieyang Peng et al.
In the field of knowledge science, understanding the structure and dynamic evolution of knowledge is essential for advancing disciplinary development and anticipating research trends. However, current methodologies lack a unified semantic f...
stSCI: A multi-task learning framework for integrative analysis of single-cell and spatial transcriptomics data [0.03%]
SCCI:单细胞和空间转录组数据综合分析的多任务学习框架
Han Shu,Jing Chen,Jialu Hu et al.
Han Shu et al.
Spatial transcriptomics (ST) preserves spatial context in gene expression analysis yet faces limitations like low resolution and RNA capture inefficiency. To address these, we present stSCI, a computational method integrating single-cell (S...
Carbon nanotubes: From disordered ensembles to van der Waals crystals [0.03%]
从无序集合到范德瓦尔斯晶体的碳纳米管研究进展
Yi Chen,Zhichun Zhang,Jiajun Chen et al.
Yi Chen et al.
Carbon nanotubes (CNTs) have ignited worldwide excitement for their extraordinary electrical and mechanical properties. Yet, despite decades of effort, realizing the "dream material" for carbon-based electronics-a wafer-scale, perfectly ali...
An efficient tissue-culture-free soybean genetic transformation technology using the extremely simple cut-dip-budding strategy [0.03%]
一种高效的无组织培养物大豆遗传转化技术——简易切割-浸泡-芽生策略
Xuesong Cao,Hongtao Xie,Zhonghui Wang et al.
Xuesong Cao et al.
Orbital-mediated local symmetry in ScAlN probed by scandium K-edge XAFS [0.03%]
基于钪K边X射线吸收精细结构的ScAlN的轨道介导局域对称性研究
Jianqiu Zhu,Xiaonan Liu,Jiye Yang et al.
Jianqiu Zhu et al.
Sustainable innovation for the clear waters of Hangzhou West Lake, China: Achievements and insights [0.03%]
中国杭州西湖的可持续创新:成就与启示
Guoliang Bai,Yadong Tang,Yunli Liu et al.
Guoliang Bai et al.
Despite many efforts and financial support, globally successful eutrophication restoration cases are rare, particularly in subtropical shallow lakes. Proposal and implementation of restoration strategy is hindered by lack of evidence in the...