Breaking the upper limit of innovation: China's dual-track regulatory framework for emerging biomedical innovations [0.03%]
突破创新上限：中国新兴生物医学创新双轨监管框架
Shawnholm Lau,Zhihong Wu,Xing Liu et al.
Shawnholm Lau et al.
Unignorable carbon sequestration potential of afforested forests in the breadbasket of the Tibetan Plateau [0.03%]
青藏高原粮仓造林林地的碳汇潜力不容忽视
Xinyao Xie,Wei Zhao,Yong Wang et al.
Xinyao Xie et al.
Cooperative integrated surgical robots for high-performance targeted therapies [0.03%]
高性能靶向治疗的协作集成外科机器人
Zhengyang Li,Zhaoyang Qi,Zehao Wu et al.
Zhengyang Li et al.
The escalating demand for secure, precise, and high-performance targeted therapies has elevated surgical robots to a prominent position in the field of robotics and translational medicine research in recent decades. However, surgical robots...
Innovation Editorial Teamzzxang@gmail.com
Innovation Editorial Teamzzxang@gmail.com
Chinese consensus on first-line precision therapy for advanced gastric cancer [0.03%]
中国晚期胃癌一线精准治疗专家共识
Xiaotian Zhang,Weiqi Sheng,Tong Xie et al.
Xiaotian Zhang et al.
Gastric cancer (GC) remains a formidable public health challenge in China, characterized by a high incidence and mortality rate. A significant proportion of patients are diagnosed with advanced or metastatic disease, where traditional chemo...
Xinyu Du,Shuang Li,Lizhi Wang et al.
Xinyu Du et al.
Fast high-resolution dental MRI using a disposable wireless intraoral coil: From concept to reality [0.03%]
一种一次性无线口腔线圈的快速高分辨率牙科磁共振成像技术：从理念到现实
Enhua Xiao,Shahzeb Hayat,Peiyu He et al.
Enhua Xiao et al.
Fast high-resolution dental MRI remains challenging due to the low signal-to-noise ratio (SNR) in small-volume tissues and the reliance on unwieldy, clinically impractical signal detection devices. In this study, we present a fast high-reso...
PROTAC-mediated regulation of programmed cell death: From molecular mechanisms to therapeutic breakthroughs [0.03%]
基于蛋白降解的细胞凋亡调控：从分子机制到精准治疗
Hangqi Huang,Aoli Deng,Feifan Pan et al.
Hangqi Huang et al.
Proteolysis-targeting chimeras (PROTACs) represent a revolutionary therapeutic strategy that achieves selective protein degradation through the ubiquitin-proteasome system, offering transformative potential for modulating programmed cell de...
Design and development of novel EGFR inhibitors spanning all subgroups of EGFR mutations in non-small cell lung cancer [0.03%]
新型表皮生长因子受体抑制剂的设计与开发用于非小细胞肺癌表皮生长因子所有突变亚群
Caolin Wang,Yiting Cen,Manzhan Zhang et al.
Caolin Wang et al.
EGFR mutations are common in non-small cell lung cancer (NSCLC), with classical mutations (L858R and exon 19 deletions [Ex19del]) and T790M mutation responsive to three generations of EGFR inhibitors (TKIs). However, the other 30% EGFR muta...
Xiang Li,Zhong Lin Wang,Di Wei
Xiang Li