Tregs in allogeneic hematopoietic stem cell transplantation (allo-HSCT): Suppressing GVHD While Preserving GVL [0.03%]
同种异体造血干细胞移植(allo-HSCT)中的Tregs:在抑制GVHD的同时保持GVL效应
Niloufar Khayam Nekouei,Negin Najjari,Nafiseh Esmaeil et al.
Niloufar Khayam Nekouei et al.
Graft-versus-host disease (GVHD) is still a significant challenge for allogeneic hematopoietic stem cell transplantation (allo-HSCT), resulting in substantial non-relapse mortality. Regulatory T cells (Tregs) are essential for modulating im...
Impact of Extramedullary Disease at Diagnosis on Outcomes Post Allogeneic Hematopoietic Cell Transplant in Children and Young Adults with Acute Myeloid Leukemia: A CIBMTR Report [0.03%]
急性髓系白血病初诊时发生髓外病变对儿童及年轻成人异基因造血干细胞移植预后的的影响：CIBMTR报告
Hemalatha G Rangarajan,Deepakbabu Chellapandian,Rasha Atshan et al.
Hemalatha G Rangarajan et al.
Background: Conflicting reports exist regarding the impact of extramedullary disease (EMD) at diagnosis upon outcomes after allogeneic hematopoietic cell transplantation (HCT) in children and young adults with acute myelo...
Letermovir prophylaxis does not hinder immune reconstitution while reshaping viral infection landscape in children Immune reconstitution under letermovir in children [0.03%]
莱托莫韦预防不影响免疫重建的同时重塑儿童病毒谱系 莱托莫韦在儿童中的免疫重建作用
Manuela Spadea,Francesca Romani,Silvia Nucera et al.
Manuela Spadea et al.
Background: Letermovir prophylaxis in adults reduces CMV-related morbidity and mortality and may delay T-cell recovery. Pediatric data are limited. Object...
Validation of the CARE-BMT Score and Proposal of a Modified Risk Model with Post-Transplant Cyclofosfamide for Predicting Early Cardiac Events after Allo-HCT [0.03%]
CARE-BMT评分的验证及提出改良风险模型用于预测allo-HCT后早期心脏事件及环磷酰胺的作用
Arnau Torrent,Enric Cascos,Esther Carcelero et al.
Arnau Torrent et al.
Background: Early cardiac events (ECE) are a recognized cause of morbidity and mortality after allogeneic hematopoietic cell transplantation (allo-HCT), especially with the widespread use of post-transplant cyclophosphami...
Optimal avidity of the Immune Synapse and mitochondrial repair trigger asymmetrical cell division and CAR T cell persistence - Review [0.03%]
免疫突触的最佳亲和力和线粒体修复触发非对称细胞分裂及CAR-T细胞的持久性-综述
Jyotishankar Raychaudhuri,Claudio Anasetti
Jyotishankar Raychaudhuri
Chimeric antigen receptor (CAR) T cell persistence with memory is the current research focus of cancer immunotherapy. The incomplete effect of CAR T cells against tumors results from CAR T cell dysfunction and exhaustion. Asymmetric cell di...
Proteomic Signatures and Early Biomarkers Predicting Veno-Occlusive Disease in Pediatric Patients Undergoing Haploidentical HSCT with Busulfan-based Conditioning and Post-Transplant Cyclophosphamide [0.03%]
基于_BUSULFAN_预处理和移植后环磷酰胺的单倍体相合HSCT儿科患者肝静脉闭塞性病的蛋白质组特征及早期生物标志物预测
Kyung Taek Hong,Suwan Yu,Jin Woo Jung et al.
Kyung Taek Hong et al.
Hepatic veno-occlusive disease (VOD), or sinusoidal obstruction syndrome, is a life-threatening complication following hematopoietic cell transplantation (HSCT). In pediatric patients, busulfan-based myeloablative conditioning is a major ri...
CD34+ selected stem cell boost provides robust outcomes in patients with poor graft function [0.03%]
CD34+选择干细胞输注可改善造血干细胞移植后植入不良患者的预后
Leland Metheny,Sayan Mullick Chowdhury,Qiuhong Zhao et al.
Leland Metheny et al.
Quality of Life and Comorbidities of Long-Term Survivors of Allogeneic Hematopoietic Cell Transplant versus their Siblings [0.03%]
allo-HSCT长期生存者与兄弟姐妹的生活质量和合并症的对比研究
Dylan E O&#x;Sullivan,Nikki Blosser,Nicole Crisp et al.
Dylan E O&#x;Sullivan et al.
Background Survivors of allogeneic hematopoietic cell transplantation (allo-HCT) are known to be at risk of late toxicities. The spectrum of late toxicities may be impacted by changing allo-HCT practices: In contemporary allo-HCT practice, ...
Second Allogeneic Hematopoietic Stem Cell Transplantation for Adult T-Cell Leukemia/Lymphoma: A Nationwide Registry Analysis [0.03%]
成人T细胞白血病/淋巴瘤二次异基因造血干细胞移植的全国登记数据分析
Makoto Yoshimitsu,Hidehiro Itonaga,Koji Kato et al.
Makoto Yoshimitsu et al.
Spatial Transcriptomics Analysis of Macrophage-to-Myofibroblast Transition in Bronchiolitis Obliterans Following Hematopoietic Stem Cell Transplantation [0.03%]
造血干细胞移植后支气管壁巨噬细胞向肌成纤维细胞转化的时空转录组分析
Akira Yamamoto,Nobuharu Fujii,Keisuke Seike et al.
Akira Yamamoto et al.
Background: Bronchiolitis obliterans (BO) is a severe, fibrotic manifestation of chronic graft-versus-host disease (GVHD) after hematopoietic stem cell transplantation (HSCT). Macrophage-derived TGF-β is linked to GVHD-r...