The iron-responsive transcription factor HapX drives iron starvation adaptation and virulence in Talaromyces marneffei [0.03%]
铁调节转录因子HapX调控马尔尼菲青霉的缺铁适应和毒力
Artid Amsri,Patcharin Thammasit,Kritsada Pruksaphon et al.
Artid Amsri et al.
Talaromycosis is an opportunistic fungal infection caused by the thermally dimorphic fungus Talaromyces marneffei. During infection, T. marneffei survives within host phagocytic cells, where it encounters iron restriction and host-derived s...
Targeting the US21 viroporin of human cytomegalovirus by calcium channel blockers as a new antiviral strategy [0.03%]
钙通道阻滞剂靶向人巨细胞病毒US21穿孔蛋白作为新的抗病毒策略
Giulia Sibille,Davide Loggia,Gianluca Catucci et al.
Giulia Sibille et al.
The Human cytomegalovirus (HCMV) US21 protein is a calcium-conducting viroporin that modulates intracellular Ca2+ homeostasis, safeguards cells from apoptosis, stimulates cell migration, and supports efficient HCMV replication. To validate ...
Genomic and structural analysis of major antigenic proteins' variability in the human relapsing fever spirochete Borrelia persica [0.03%]
伯氏疏螺旋体主要抗原蛋白变异性的基因组和结构分析
Dor Shwartz,Yaarit Nachum-Biala,Reinhard K Straubinger et al.
Dor Shwartz et al.
Antigenic variation enables immune evasion of pathogens, yet the mechanisms for the rapid change in their antigens without loss of structural and functional features are not fully known. Tick-borne relapsing fever (TBRF) spirochetes of the ...
Lineage-specific endosymbiosis in Mucorales: restriction of Mycetohabitans to the genus Rhizopus [0.03%]
黏菌纲中门微生物的谱系特异性内共生现象：Mycetohabitans属仅限于毛霉属分类单元之内
Na Li,Jochem Buil,Qi-Rui Li et al.
Na Li et al.
Endosymbiotic bacteria have been reported in mucoralean fungi, yet their taxonomic distribution, range of ecological niches, and host specificity remain incompletely understood. Clarifying the occurrence of these bacterial partners across c...
Unexplored biosynthetic gene clusters in bacteria isolated from Brazilian stingless bee honey with activity against multidrug-resistant pathogens [0.03%]
来源于巴西无刺蜂蜂蜜细菌中的未探索生物合成基因簇及其对耐多药病原菌的活性
José Fhilipe De Miranda Da Silva,Carlos Filipe Ribeiro de Matos,Larissa Martins Moura et al.
José Fhilipe De Miranda Da Silva et al.
The emergence of new infectious diseases and the development of microbial resistance to existing drugs, accompanied by a decline in the discovery of new antibiotic classes through traditional approaches, highlight the urgent need for novel ...
Diverse and significant microbe-mediated mineral transformation in deep-sea hydrothermal vent indicated by Methylophaga, Sulfitobacter and Roseovarius [0.03%]
来源于甲基罗布氏菌、硫磺杆噬菌体和玫瑰杆菌的多样的深海热液口微生物介导的矿物转化证据
Minghua Liu,Yingwen Zhong,Yi Ding et al.
Minghua Liu et al.
Microbe-mineral interactions play a crucial role in microbial energy conservation and mineral mobilization within deep-sea hydrothermal vents, yet the specific microorganisms involved remain largely underexplored. In this study, sulfide min...
Metagenomics reveals the functional profiles of soil microorganisms and nutrient cycling under long-term grass vegetation cropping [0.03%]
基于长期草被种植的土壤微生物群落宏基因组及其养分循环功能解析
Hengkang Xu,Jiale Guo,Chao Chen et al.
Hengkang Xu et al.
Soil microbes are crucial for biogeochemical cycles and their functional potential is greatly affected by ecosystem management. Yet, how does grass vegetation affect the composition of soil microbial communities and the abundance of key nut...
Genetic engineering of gut commensals: heterologous protein expression in Bifidobacterium animalis subsp. lactis CECT8145 [0.03%]
乳酸动物双歧杆菌CTEC8145中异源蛋白表达及肠道共生菌的基因工程改造研究
Alba Arévalo-Lalanne,Paola Corbín-Agustí,Daniel Ramón et al.
Alba Arévalo-Lalanne et al.
Bifidobacterium is a key genus of the gut microbiota. Among commercially used probiotics, Bifidobacterium animalis subsp. lactis CECT 8145 has been shown to exert health benefits in metabolic health and healthy aging. Remarkably, these effe...
Assessing endometrial microbiota in endometriosis: culturomics and sequencing analysis of receptive-phase tissue [0.03%]
内异症种植窗期子宫内膜微生物组的培养和测序分析
A Canha-Gouveia,C M Tenorio,T Rööp et al.
A Canha-Gouveia et al.
Endometriosis has been associated with alterations in the reproductive tract microbiota, yet studies focusing on the endometrial microbiome remain inconsistent, partly due to the low-biomass nature of this niche and methodological heterogen...
Microbial community characterization in semi-hydroponic systems of Starbor kale (Brassica oleracea L.) grown under normal gravity and simulated microgravity [0.03%]
模拟微重力条件下常规重力培育的抱子甘蓝（芸苔属）半水培系统中微生物群落特征分析
Labode Hospice Stevenson Naitchede,Onyinye C Ihearahu,Kishan Saha et al.
Labode Hospice Stevenson Naitchede et al.
Kale is a member of the Brassicaceae family and contains a range of beneficial compounds. Given the global context of climate change, various vegetable production systems using advanced technologies, such as hydroponics, are being explored ...