Mutations in the superoxide-responsive regulator SoxR confer fluoroquinolone resistance in Stenotrophomonas maltophilia [0.03%]
SOXR蛋白中的一种超氧阴离子响应调节因子的突变可赋予麻风分枝杆菌氟喹诺酮类耐药性
Poonyaporn Kanawong,Parinya Tipanyo,Suleepon Poomchuchit et al.
Poonyaporn Kanawong et al.
Stenotrophomonas maltophilia is a multidrug-resistant Gram-negative opportunistic pathogen. Its antimicrobial resistance arises from intrinsic traits and acquired mechanisms. Overexpression of drug efflux transporters is one of the key mech...
Uncovering the endophytic bacterial diversity and crop improvement potential under salinity stress in the halophyte Halocnemum strobilaceum [0.03%]
盐胁迫下卤碱植物Halocnemum strobilaceum内生细菌多样性及其农作物改良潜能的挖掘
Elena Romano-Rodríguez,Noris J Flores-Duarte,Eloísa Pajuelo et al.
Elena Romano-Rodríguez et al.
Halophytes are considered promising sources of halophilic and halotolerant bacteria for biotechnological applications in agriculture, particularly as soil salinization threatens crop yield. Although interest in halophyte-associated endophyt...
Bacterial warfare at the molecular level: Pseudoalteromonas sp. H2 disrupts Vibrio splendidus membrane integrity via ClpP-CheW2 regulation [0.03%]
分子水平上的细菌作战：荧光假单胞菌H2通过ClpP-CheW2调节紊乱灿烂弧菌膜的完整性
Ya Li,Fa Dai,Weibo Shi et al.
Ya Li et al.
In mariculture ecosystems where Vibrio spp. are predominant pathogens, effective biocontrol through antagonistic probiotics remains an unresolved biological challenge. Here, the Pseudoalteromonas sp. H2 strain was first determined to inhibi...
Manganese homeostasis supports Stenotrophomonas maltophilia oxidative stress defense and replication in Acanthamoeba castellanii phagosomes [0.03%]
锰代谢稳态支持斯氏假单胞菌氧化应激反应以及在哈坎托克斯体包囊中的复制能力
Fulvia-Stefany Argueta-Zepeda,Javier Rivera,Julio César Valerdi-Negreros et al.
Fulvia-Stefany Argueta-Zepeda et al.
Manganese homeostasis is essential for the environmental adaptability and pathogenic potential of Stenotrophomonas maltophilia, a bacterium that thrives across diverse and fluctuating environments. Here, we characterize the manganese homeos...
Multi-omics analysis-based insights into the microbial community composition and flavor development potentiality of different varieties of sorghum (Sorghum bicolor L. Moench) fermented into Sesame flavor Baijiu [0.03%]
基于多组学分析的高梁品种差异发酵生成芝麻香型白酒的微生物群体构成及风味潜力研究
Meina Jiang,Jiaxin Tang,Angui Lai et al.
Meina Jiang et al.
Sorghum is a key raw ingredient in the fermentation of Sesame-flavor Baijiu (SFB). However, studies on the microbial and metabolic dynamics of sorghum varieties on SFB fermentation is limited. In this study, microbial and flavor differences...
Metagenomic profiling of ocular surface microbiome alterations in patients with progressive supranuclear palsy-Richardson's syndrome [0.03%]
进行性核上性麻痹-理查森综合征患者眼表微生物组的元基因组分析
Rui Zhang,Yong-Kang Chen,Qing-Yong Zhu et al.
Rui Zhang et al.
This study employed shotgun metagenomic sequencing to characterize the ocular surface microbiome in 20 progressive supranuclear palsy-Richardson's syndrome (PSP-RS) patients, 17 Parkinson's disease (PD) patients, and 30 healthy controls (HC...
Bifidobacterium stercoris KC84 attenuates IBS-D-like symptoms via modulation of serotonin-related pathways and dendritic cell-mediated IFN-β induction [0.03%]
粪产碱杆菌KC84通过调节五羟色胺相关途径和树突细胞介导的IFN-β诱导缓解腹泻型肠易激综合征症状
Seokcheon Song,Myeonghwan Han,Kwanwoo Moon et al.
Seokcheon Song et al.
Irritable bowel syndrome with diarrhea (IBS-D) is a prevalent disorder that significantly impairs quality of life, yet therapeutic advances remain limited. Serotonin dysregulation, primarily driven by enterochromaffin cells in the intestina...
The genome-scale sugar metabolic model from Neurospora crassa reveals lower gene redundancy than that of Aspergillus niger [0.03%]
源自Neurospora crassa的基因组规模糖代谢模型揭示了其基因冗余度低于Aspergillus niger
Jiajia Li,Mao Peng,Bo Baas et al.
Jiajia Li et al.
The filamentous fungus Neurospora crassa has been a model organism for understanding many fundamental aspects of eukaryotic biology. Here, we constructed a genome-scale model of its sugar metabolism based on the sugar metabolic model of Asp...
Transcriptional and cellular reprogramming in Anabaena sp. PCC7120 biofilms: implications for stress response [0.03%]
固氮蓝藻被囊中的转录和细胞重组：对压力响应的影响
Irene Olivan-Muro,Alodia Liesa,Emma Sevilla et al.
Irene Olivan-Muro et al.
Cyanobacteria are major components of phototrophic biofilms, driving critical biogeochemical cycles and offering sustainable solutions for agriculture. However, the factors governing their transition from planktonic to sessile lifestyles re...
Probiotic-driven microbiome remodeling is associated with coordinated immune and metabolic responses, improving growth and disease resistance in farmed tongue sole (Cynoglossus semilaevis) [0.03%]
益生菌驱动的肠道微生物组重塑与养殖黑斑侧带舌齿鱼生长和疾病抵抗力改善相关的免疫和代谢反应同步协调
Yuanri Hu,Xu Yan,Fengtao Gao et al.
Yuanri Hu et al.
In flatfish aquaculture, labour-intensive tank cleaning represents a major operational challenge, limiting sustainability due to its high labour requirements and associated costs. We tested a new semi-closed recirculating aquaculture system...