Editorial for special issue "Microorganisms and food security under climate change scenarios: From taxonomy to host-microbe interactions" [0.03%]
特刊 “气候变化下的微生物与粮食安全：从分类学到宿主-微生物相互作用”序言
Brenda Román-Ponce,Fernando Uriel Rojas-Rojas
Brenda Román-Ponce
•Climate change and environmental stressors are major drivers affecting global food security and agricultural sustainability.•Microbial communities play a central role in nutrient cycling, plant health, and ecosystem resilience.•Climate ...
Association between secondhand smoke exposure and ocular microbiome changes in children [0.03%]
儿童被动吸烟与眼部微生物群变化的关系
Qihang Sun,Xiangtian Ling,Yuzhou Zhang et al.
Qihang Sun et al.
Purpose: To investigate whether secondhand smoke (SHS) exposure alters the ocular surface microbiome (OSM) in children and to explore potential functional consequences. ...
Endogenous hydrogen sulfide reprograms mitochondrial respiration and modulates pathogenicity in Ustilago maydis [0.03%]
内源硫化氢可重新设定Ustilago maydis的线粒体呼吸并调节其致病性
Emilio Espinoza-Simón,Nayeli Torres-Ramírez,Margarita Juárez-Montiel et al.
Emilio Espinoza-Simón et al.
Sulfur metabolism is a central determinant of microbial physiology and adaptation to environmental conditions. Hydrogen sulfide (H2S), a reactive sulfur species produced during cysteine metabolism, has recently emerged as a key regulator of...
Targeting cyclic di-AMP signaling through diadenylate cyclase inhibition reduces methicillin resistance in clinical MRSA isolates [0.03%]
靶向抑制二腺苷酸环化酶可降低临床分离的耐甲氧西林金黄色葡萄球菌的耐药性
Niti Kumari,Itishree Jali,Priyanka Garg et al.
Niti Kumari et al.
Background: Methicillin-resistant Staphylococcus aureus (MRSA) remains a major clinical challenge due to persistent β-lactam resistance and biofilm-associated tolerance. While canonical resistance mechanisms are well def...
Meropenem stress drives lipid remodeling and resistance gene dissemination via outer membrane vesicles in carbapenem-resistant Klebsiella pneumoniae [0.03%]
美罗培南压力通过碳青霉烯耐药肺炎克雷伯菌的外膜囊泡驱动脂质重塑和抗性基因传播
Fangfang Fan,Qiuyuan Shi,Guangzhang Chen et al.
Fangfang Fan et al.
Carbapenem-resistant Klebsiella pneumoniae (CRKP) has emerged as a critical global health threat, fueled by escalating antibiotic resistance rates among clinical isolates. This study investigates the adaptive responses of CRKP to meropenem,...
Organic acid-based deep eutectic solvents (DESs) are potent antimicrobial agents against antibiotic-resistant bacteria and viruses [0.03%]
基于有机酸的深吴溶剂（DES）对耐抗生素细菌和病毒具有强大的抗菌活性
Mohamed Abdelfattah Maky,Yanath Belguesmia,Chérifa Obone Opimba et al.
Mohamed Abdelfattah Maky et al.
The escalating threat of antibiotic-resistant bacteria, biofilms and viral contamination in the healthcare and food industries threatens global health and requires the development of innovative antimicrobials. Deep eutectic solvents (DESs) ...
Nutrient-driven small-colony variants as an adaptive outcome in Carbapenem-resistant Acinetobacter baumannii [0.03%]
卡培姆抗生素耐药性巴氏不动杆菌中营养驱动的小菌落变异体是一种适应性的结果
Samyar Moheb,Shayra D Sanchez,Irene Luu et al.
Samyar Moheb et al.
Carbapenem-resistant Acinetobacter baumannii (CRAB) is a serious threat, and resistance is emerging to cefiderocol, one of the few remaining treatment options. However, how host micronutrients drive bacterial adaptation under antibiotic pre...
Integrated omics reveal a unique antibacterial mechanism of action for the small molecule HSI#6 [0.03%]
整合组学揭示小分子HSI的功能机制
Haitham Sedky,Mohamed Belal Hamed,Kurt Vermeire et al.
Haitham Sedky et al.
The continuous risk of antibiotic resistance development underscores the demand for new agents with mechanisms distinct from existing antibacterial drugs. Here, we investigated HSI#6, a small-molecule antibacterial previously identified as ...
Smolstatin1, a unique cystatin-like stefin of Sphaerospora molnari, is essential for parasite development [0.03%]
Smolstatin1是Sphaerospora molnari中的一种独特胱抑素样stefin，对寄生虫发育至关重要
Pavla Bartošová-Sojková,Tamás Dobai,Jiří Kyslík et al.
Pavla Bartošová-Sojková et al.
Stefins, members of the cystatin superfamily, regulate cysteine proteases, yet their roles in early-branching metazoans remain poorly defined. Here, we characterize Smolstatin1, a cystatin-like stefin from the myxozoan Sphaerospora molnari,...
Antiviral potential of black tea and blueberry extracts against monkeypox virus by targeting orthopoxvirus surface proteins [0.03%]
针对正痘病毒表面蛋白的猴痘病毒抑制剂：黑茶和越橘提取物的抗病毒潜力研究
Yi&#x;ou Sha,Yixin Li,Yanchen Liu et al.
Yi&#x;ou Sha et al.
Monkeypox virus (MPXV) outbreaks primarily affect resource-limited regions in Africa, highlighting an urgent need for low-cost, accessible therapeutics. Food-medicine homologous (FMH) substances, which are bioactive food components with med...