Enhancing diagnostic efficiency of pyrazinamide resistance in Mycobacterium tuberculosis via modified MGIT assay and genotypic correlation [0.03%]
改良MGIT检测结合基因型分析提高结核分枝杆菌吡嗪酰胺耐药的诊断效率
Ananthi Rajendran,Ahmed Kabir Refaya,Balaji Subramanyam et al.
Ananthi Rajendran et al.
Pyrazinamide (PZA) plays a crucial role in the treatment of both active and latent tuberculosis, particularly in regimens designed to treat drug-resistant TB. However, diagnosing resistance to PZA poses challenges for managing TB, highlight...
Advances in the type IX secretion system: an exploration focusing on Riemerella anatipestifer [0.03%]
第九型分泌系统研究进展及鸭疫巴氏杆菌的探索性研究
Pengfei Niu,Rong Guo,Chan Ding et al.
Pengfei Niu et al.
The type IX secretion system (T9SS) is specific to the Fibrobacteres-Chlorobi-Bacteroidetes superphylum, the members of which have many specialized features, including gliding motility and the transport of cargo proteins across the outer me...
Geographical and environmental factors influence snow microbial communities in city and suburban areas of Northern China [0.03%]
城市和郊区地理和环境因素对中国北部雪微生物群的影响
Hengkang Xu,Yuchuan Shi,Siyi Wang et al.
Hengkang Xu et al.
The response of snow microbial communities to environmental variations represents a critical topic in ecological research, particularly given that winter snowfall constitutes the main form of precipitation in northern China. In this study, ...
A T cell-based ubiquitin-mediated mRNA vaccine provides cross-protection against H1N1 and B influenza viruses in mice [0.03%]
基于T细胞的泛素介导的mRNA疫苗可使小鼠针对H1N1和B型流感病毒产生交叉保护作用
Yaxin Di,Ziliang Wang,Zilin Ren et al.
Yaxin Di et al.
Given the persistent antigenic drift of seasonal influenza viruses and the continuous threat of emerging pandemics, there is an urgent necessity to develop novel influenza vaccines capable of conferring broad-spectrum immunity against multi...
Cold stress enhances cryotolerance in Lacticaseibacillus rhamnosus B6 via membrane lipid remodeling and differential protein expression [0.03%]
冷胁迫通过膜脂重塑和差异蛋白表达增强Lacticaseibacillus rhamnosus B6的冻耐受性
Ting Yang,Jia Zhang,Ranjin Zhang et al.
Ting Yang et al.
Understanding the molecular mechanisms underlying the cryotolerance of lactic acid bacteria is critical for preserving their viability in food processing. In this study, Lacticaseibacillus rhamnosus B6 and KF7 with different phenotypic prop...
Supragingival microbial profiles in caries-free and caries-active adolescents treated with fixed orthodontics [0.03%]
固定正畸矫治者的无龋和患龋青少年的龈上微生物特征
Xiaoyu Miao,Henglong Cao,Jin Chen et al.
Xiaoyu Miao et al.
Background: Dental caries occur primarily due to the formation of excessive dental plaque biofilm on teeth surfaces. This study aims to analyze the supragingival microbial profiles of permanent teeth in caries-free and ca...
Genomic evolution, antimicrobial resistance, and dissemination of global Serratia spp. unveil increasing species diversity and carbapenemae‑resistance: A retrospective and genomic epidemiology study [0.03%]
霍乱弧菌的进化、抗微生物药物耐药性及全球志贺氏不动杆菌的传播揭示了日益增长的物种多样性以及碳青霉烯耐药性的增加：一项回顾性和基因组流行病学研究
Wentao Zhu,Xi Chen,Hong Shen et al.
Wentao Zhu et al.
Serratia spp., an opportunistic pathogen, has increasingly acquired resistance, particularly the emergence of carbapenemase-resistance. However, previous studies have focused on fragmented surveillance and have not conducted overall correla...
The role of opsonophagocytosis in killing of Klebsiella pneumoniae in human blood [0.03%]
人血中杀死肺炎克雷伯菌的调理吞噬作用的作用
Charlotte Mejlstrup Hymøller,Trine S Jensen,Pernille Vigsø Rasmussen et al.
Charlotte Mejlstrup Hymøller et al.
Klebsiella pneumoniae is an opportunistic, gram-negative pathogen causing life-threatening sepsis in patients with co-morbidity. In contrast, in healthy persons, K. pneumoniae rarely causes sepsis. To elucidate how K. pneumoniae is eliminat...
Shifting seas and first feeds: gut microbiome dynamics in juvenile chum salmon (Oncorhynchus keta) and their climate vulnerability [0.03%]
变幻的海洋和最初的觅食：狗鱼大麻哈鱼（Oncorhynchus keta）肠道微生物组动态及其气候脆弱性
Subrata Kumar Ghosh,Marty Kwok-Shing Wong,Susumu Hyodo et al.
Subrata Kumar Ghosh et al.
Background: The early development of host-associated microbiota is crucial for host health and resilience. In migratory fish like chum salmon, the transition from freshwater to seawater and the onset of feeding are critic...
Microbial dark matter spearheading the biogeochemical cycle in the Solar Lake of Taba, Egypt [0.03%]
埃及塔巴太阳湖地质化学循环中的微生物暗物质
Rehab Z Abdallah,Ali H A Elbehery,Amged Ouf et al.
Rehab Z Abdallah et al.
Microbial dark matter (MDM) represents a vast, uncultured fraction of microbial life with largely unknown ecological roles, particularly in extreme environments. This study investigates MDM in the hypersaline microbial mats of Solar Lake, T...