Chemotherapy-induced diminished murine ovarian reserve model and impact of low-dose chemotherapy on fertility [0.03%]
化疗诱导的小鼠卵巢储备减少模型及低剂量化疗对生育力的影响
Lara Houeis,Graziella van der Plancke,Jen-Yu Wen et al.
Lara Houeis et al.
Objective: To establish a murine model of chemotherapy-induced diminished ovarian reserve (DOR) and investigate residual fertility after chemotherapy exposure. ...
Luteinizing hormone receptor deficiency in immature cumulus-oocyte complexes retrieved for assisted reproduction [0.03%]
卵母细胞体外成熟中黄体生成素受体缺乏对其后续发育的影响
Maíra Casalechi,Maria Thereza V Pereira,Wiviane A Assis et al.
Maíra Casalechi et al.
This study investigated whether luteinizing hormone receptor (LHR) expression varies in the granulosa cells of individual follicles according to the maturation stage of the oocytes harvested for assisted reproductive technology (ART) treatm...
Relugolix reduces leiomyoma extracellular matrix production via the TGF β pathway [0.03%]
Relugolix通过TGFβ途径减少子宫肌瘤的细胞外基质产生
Adina Schwartz,Minnie Malik,Paul Driggers et al.
Adina Schwartz et al.
Objective: To determine if the oral GnRH antagonist relugolix affects leiomyoma extracellular matrix production through the TGF β pathway DESIGN: Laboratory Study SUBJECTS: None. ...
Amir Mokhtare,Amirhossein Favakeh,Philip Xie et al.
Amir Mokhtare et al.
Objective: To introduce an innovative non-contact method for denudation process of cumulus-oocyte complexes (COCs) for intracytoplasmic sperm injection (ICSI). ...
Direct Assessment of Hereditary Hemochromatosis in Preimplantation Genetic Testing [0.03%]
植入前基因筛查中遗传性血色病的直接评估
Qinnan Zhang,Maria Katz,Benjamin Podgursky et al.
Qinnan Zhang et al.
Objective: Hereditary hemochromatosis (HH) is a common genetic disorder characterized by iron overload, which, if undiagnosed, can lead to severe organ damage. There are four types of HH. Type 1 HH, the most common form, ...
Uterine pathology and microbiome among patients with endometrial polyps and fibroids [0.03%]
子宫息肉和肌瘤患者的病理及微生物群分析
Sabrine Bensouda,Sarah C Cromack,Allison S Komorowski et al.
Sabrine Bensouda et al.
Objective: To evaluate the uterine microbiome among women with endometrial polyps and submucosal fibroids and to compare results between endometrial sampling techniques. ...
Mitochondrial activator BGP-15 protects sperm quality against oxidative damage and improves embryo developmental competence [0.03%]
线粒体激活剂BGP-15保护精子质量免受氧化损伤并提高胚胎发育潜能
Macarena B Gonzalez,Nicole O McPherson,Haley S Connaughton et al.
Macarena B Gonzalez et al.
Objective: To study the efficacy of mitochondrial activator BGP-15 to preserve sperm quality and competence against cellular damage. Design: ...
Receptive window might be shorter in patients with endometriosis and lesions cyclically prepare for implantation [0.03%]
子宫内膜异症患者接受窗可能较短且病灶周期性准备植入
Nirukshi Samarajeewa,Sophea Heng,Ying Li et al.
Nirukshi Samarajeewa et al.
Objective: To investigate whether endometrial receptivity is affected in patients with endometriosis using podocalyxin (PCX) as a functional biomarker; to study how endometriotic lesions display PCX and the potential path...
Sphingosine 1-phosphate acts as proliferative and fibrotic cue in leiomyoma cells [0.03%]
鞘氨醇-1-磷酸作为平滑肌瘤细胞增殖和纤维化的信号分子
Margherita Rossi,Isabelle Seidita,Matteo Prisinzano et al.
Margherita Rossi et al.
Objective: To determine whether the bioactive sphingolipid sphingosine 1-phosphate (S1P) modulates cellular proliferation and synthesis of fibrotic proteins in leiomyoma differently than myometrial cells. ...
Blood-based inflammatory markers in female infertility: evidence from Mendelian randomization analysis [0.03%]
基于女性不孕的血液炎症标志物：来自孟德尔随机化分析的证据
Simon Alesi,Helena Teede,Joanne Enticott et al.
Simon Alesi et al.
Objective: To investigate causal associations between blood-based inflammatory markers and female infertility using Mendelian randomization (MR). Design: ...