Utilization of a 3D in vitro co-culture system to characterize embryonic mechanisms associated with implantation [0.03%]
利用三维体外共培养系统来研究与胚胎着床相关的作用机制
Keelee J McCarty,Blair McCallie,William B Schoolcraft et al.
Keelee J McCarty et al.
Objective: Implantation success is dependent on timely molecular signaling to establish embryonic apposition, adhesion and invasion. In an effort to elucidate this critical period in human reproduction, the objective of t...
Stearoyl-coenzyme A desaturase enhances cell survival in human uterine leiomyoma [0.03%]
月见草酸CoA脱 saturase提高人子宫肌瘤细胞的存活率
Allison S Komorowski,John S Coon V,Melania Anton et al.
Allison S Komorowski et al.
Objective: Stearoyl-CoA desaturase (SCD1) is an enzyme that catalyzes the conversion of saturated delta-9 fatty acids to monounsaturated fatty acids. SCD1 is highly expressed in various cancers and facilitates cancer cell...
Impact of a Short-Term Western-Style Diet and Hyperandrogenism on Adult Rhesus Macaque Ovarian Function [0.03%]
西式饮食和高雄性激素对恒河猴卵巢功能的影响
Pamela B Parker,Melinda J Murphy,Sweta Ravisankar et al.
Pamela B Parker et al.
Objective: To determine the effect of an obesogenic Western-style diet and hyperandrogenemia on ovarian outcomes. Design: Experimental,...
Bupropion, the atypical antidepressant used in smoke cessation: an in vitro study on its effects on human sperm function [0.03%]
布普品，一种用于戒烟的非典型抗抑郁药：一项关于其对人精子功能影响的体外研究
Maria Brito,Ana Gonçalves,Alberto Barros et al.
Maria Brito et al.
Objective: To assess the effects of the active metabolite of Bupropion (BUP), hydroxybupropion (OH-BUP), on human spermatozoa in vitro. Design: ...
The dual nature of micronutrients on fertility: too much of a good thing? [0.03%]
微量营养元素对生育的双重影响：物极必反？
Aron Moazamian,Elisa Hug,Pauline Villeneuve et al.
Aron Moazamian et al.
Objective: To study the effects of generally considered safe doses of antioxidant micronutrient supplementation on semen parameters, systemic redox balance, sperm DNA structural integrity, and fertility. ...
Prioritization of potential drug targets in ovarian-related diseases: Mendelian randomization and colocalization analyses [0.03%]
卵巢相关疾病潜在药物靶点的优先排序：孟德尔随机化和共定位分析
Yanggang Hong
Yanggang Hong
Objective: To identify key genes and potential drug targets for ovarian-related diseases through genome-wide Mendelian randomization (MR) and colocalization analyses. ...
Genetic insights into the immunological basis of male infertility: A translational perspective [0.03%]
男性不育的免疫学基础的遗传见解：转化医学的角度
Yi Wang,Yanggang Hong
Yi Wang
Objective: To clearly elaborate the causal relationships between specific immunocyte phenotypes and male infertility. Design: Mendelian...
Effect of endometriosis-linked microRNAs on hepatic gene expression [0.03%]
与子宫内膜异位症相关的microRNA对肝基因表达的影响
Ramanaiah Mamillapalli,Rebecca Slutzky,Anjali Mangala et al.
Ramanaiah Mamillapalli et al.
Objective: To determine if microRNAs that are altered in the circulation of women with endometriosis affect metabolic gene expression in hepatic cells. De...
Polycystic ovary syndrome and morphokinetic embryonic development: A case-control study evaluating 791 embryos [0.03%]
多囊卵巢综合征与胚胎动力学发育：一项纳入791枚胚胎的病例对照研究
Gilad Karavani,Shira Shapira-Nass,Natali Schachter-Safrai et al.
Gilad Karavani et al.
Objective: To investigate the association between Polycystic Ovary Syndrome (PCOS) and the rate of embryo development, using time-lapse monitoring systems (TLM), compared to a control group of women with mechanical (tubal...
Enhanced Ovarian FKBP51 Expression is Associated with Ovarian Aging: A Molecular Insight for Age-Related Fertility in Women [0.03%]
卵巢FKBP51表达增强与卵巢衰老相关：女性年龄相关生育能力的分子见解
Papri Sarkar,Monica Moore,Asli Ozmen et al.
Papri Sarkar et al.
Objective: To study the relationship between FK506-binding protein 51 (FKBP51) and ovarian aging and/or diminished ovarian reserve (DOR) in human ovaries by comparing FKBP51 levels in granulosa (GC) and cumulus cells (CC)...