Dose-Dependent Modulation of LH Receptor Expression in Human Granulosa Cells and Progesterone Production During Ovarian Stimulation [0.03%]
剂量依赖性调节促黄体生成素受体在人类颗粒细胞中的表达以及在卵巢刺激过程中的孕酮产生
Barbara Lawrenz,Sahar Ghafari,Erkan Kalafat et al.
Barbara Lawrenz et al.
Objective: To assess the impact of different recombinant (rec)FSH dosages in ovarian stimulation (OS) on LH-receptor- and FSH-receptor expression in granulosa cells (GC) and progesterone level. ...
Complementary Therapeutic Actions of Shikonin and Indolepropionic Acid Ameliorate Diabetic Infertility via Distinct Antioxidant and Metabolic Pathways [0.03%]
基于紫草素和吲哚丙酸互补的疗法通过不同的抗氧化和代谢途径改善糖尿病不育症
Imran Tarique,Ali Haider,Fatima Nawazish
Imran Tarique
Objective: To evaluate the effect of Shikonin, a potent direct ROS scavenger, and Indolepropionic acid (IPA), a microbiome-derived metabolite, on epididymis and sperm morphology and function in diabetic rats. ...
Functional stability of the second mitotic spindle in blastomeres and its association with multinucleation repair [0.03%]
第二次有丝分裂纺锤体在卵裂球中的功能稳定性及其与多核修复的关联性研究
Taichi Sakaguchi,Hiromitsu Shirasawa,Yuki Ono et al.
Taichi Sakaguchi et al.
Objective: To study mitotic spindle morphology and chromosomal segregation in second mitosis. Design: Live-cell imaging of DNA and tubu...
Euploid but failing to implant? Insights from trophectoderm transcriptomics of euploid blastocysts using an in vitro model [0.03%]
染色体正常但着床失败？通过体外模型正常二倍体囊胚滋养层转录组研究提供新见解
David Ortega-Jaén,Antonio Capalbo,Ángel Martín et al.
David Ortega-Jaén et al.
Objective: To investigate transcriptomic differences in mural trophectoderm (TE) cells of euploid human blastocysts based on their ability to remain attached in extended in vitro culture, and to identify gene expression p...
The work of science is to substitute facts for appearances, and demonstrations for impressions [0.03%]
用事实代替表象，用实证代替印象才是科学的工作。
William H Catherino
William H Catherino
Environmental factors accelerate epigenetic aging of sperm via mechanistic target of rapamycin/blood-testes barrier mechanism [0.03%]
环境因素通过雷帕霉素信号靶点/血睾屏障机制加速精子表观遗传衰老
Olatunbosun Arowolo,Oladele A Oluwayiose,Jiahui Zhu et al.
Olatunbosun Arowolo et al.
Background: Research on sperm epigenetics demonstrated that DNA methylation patterns in spermatozoa may be affected by a broad range of environmental factors, health conditions, and aging. It was also shown that these cha...
The Dual Role of IL-22: Balancing Protection and Risk in Pregnancy during Inflammatory Challenges [0.03%]
IL-22的双重作用：在炎症挑战下的妊娠期平衡保护与风险
Umida Ganieva,Mahmood Bilal,Ana Adam et al.
Umida Ganieva et al.
Objective: To investigate the potential of recombinant IL-22 (rIL-22) in preventing inflammation-triggered abortion. Design: Using wild...
Transvaginal Shear Wave Elastography for Measuring Uterine Myometrial and Leiomyoma Stiffness: a Protocol Pilot Study [0.03%]
盆腔剪切波弹性成像测量子宫肌瘤及周围肌层硬度的临床应用价值研究方案报告
Hannah T Ryles,Sumeyra Agambayev,Mervat Omran et al.
Hannah T Ryles et al.
Objective: Recent studies suggest that the stiffness of uterine leiomyomas may be related to their growth and behavior. Shear wave elastography, a quantitative method of measuring tissue stiffness, has been increasingly s...
PGR Isoform modulation via enhancer activation regulates progesterone signaling in endometrial stromal cells [0.03%]
宫腔内膜间质细胞中增强子激活介导的PGR异构体调节调控孕酮信号通路
Skylar G Montague Redecke,Austin Bell-Hensley,MyeongJin Yi et al.
Skylar G Montague Redecke et al.
Objective: To investigate enhancer-mediated regulation of progesterone receptor (PGR) isoforms, PGR-A and PGR-B, in human endometrial stromal cells, and to determine how isoform modulation shapes the progesterone-responsi...
Use of AMD3100 for Bone Marrow Derived Mesenchymal Stem Cells Mobilization in the Treatment of Murine Asherman's Syndrome [0.03%]
AMD3100动员骨髓来源间充质干细胞治疗小鼠Asherman综合征的研究
V A Flores,P A Delis,R Mamillapalli et al.
V A Flores et al.
Objective: Asherman's syndrome (AS) is characterized by intrauterine adhesions/fibrosis, resulting from damage to the endometrial basalis layer. The consequences of AS include infertility, recurrent pregnancy loss, preter...