Effect of an autism-associated KCNMB2 variant, G124R, on BK channel properties [0.03%]
自闭症相关KCNMB2基因变异体G124R对BK通道性质的影响
Hans J Moldenhauer,Ria L Dinsdale,Sara Alvarez et al.
Hans J Moldenhauer et al.
BK K+ channels are critical regulators of neuron and muscle excitability, comprised of a tetramer of pore-forming αsubunits from the KCNMA1 gene and cell- and tissue-selective β subunits (KCNMB1-4). Mutations in KCNMA1 are associated with...
Effects of carbohydrate-electrolyte dissolved alkaline electrolyzed water on physiological responses during exercise under heat stress in physically active men [0.03%]
碳水化合物电解质溶解碱性电解水对热应力下运动时的生理反应的影响
Shohei Dobashi,Tomohiro Kobayashi,Yoshinori Tanaka et al.
Shohei Dobashi et al.
Purpose: This study investigated the effects of 1400 mL intake of alkaline electrolyzed water (AEW) or purified water (PW) into which carbohydrate-electrolyte (CE) was dissolved on improving physiological responses during...
Blockade of vasopressin receptors reduces the threshold pressure of micturition reflex in female rats [0.03%]
血管加压素受体阻滞降低雌性大鼠排尿反射的压力阈值
Luciana S S Neri,Rodrigo P de Carvalho,Sergio A Daiuto et al.
Luciana S S Neri et al.
The mechanisms involved in urinary bladder control are not fully understood, but it is well accepted that a complex central network is involved in micturition control. The micturition reflex can be modulated by direct cortical influence thr...
Evaluation of the sex steroids mediated modulation of leucocyte immune responses in an ophidian Natrix piscator [0.03%]
蛇(Natrix piscator)中性激素介导的免疫反应评估
Alka Singh,Ramesh Singh,Manish Kumar Tripathi
Alka Singh
The immune-suppressive role of sex steroids in mammals is well documented, but information on other vertebrates is limited. The present study was planned to analyze the effect of testosterone and progesterone in the modulation of immune fun...
Modulatory roles of melatonin on respiratory and heart rates and their circadian rhythmicity in donkeys (Equus asinus) subjected to packing during the hot-dry season [0.03%]
夏季炎热干燥季节骡子负重时褪黑素对心率和呼吸频率及其昼夜节律调制作用的研究
Joseph Olusegun Ayo,Ayodele Stephen Ake
Joseph Olusegun Ayo
In mammals a central circadian clock is located in the suprachiasmatic nuclei of the hypothalamus, which regulates the innate physiological rhythms to the ambient 24-h light-dark cycle. Melatonin is an essential component of circadian rhyth...
Sustained hypoxia in mice increases parasympathetic but not sympathetic tone [0.03%]
持续低氧增加小鼠副交感神经但不增加交感神经紧张度
Juliana R Souza,Mauro de Oliveira,Benedito H Machado
Juliana R Souza
The autonomic profile of mice submitted to sustained hypoxia (SH) was not yet fully evaluated. Herein, we characterized the cardiovascular and autonomic profile of conscious freely moving mice submitted to SH using two sequential experiment...
Biochemical properties of H+-Ca2+-exchanger in the myometrium mitochondria [0.03%]
人子宫平滑肌细胞线粒体H+-Ca2+交换器的生化性质研究
Yurii V Danylovych,Hanna V Danylovych,Oksana V Kolomiets et al.
Yurii V Danylovych et al.
Some biochemical properties of the H+-Ca2+-exchanger in uterine smooth muscle mitochondria have been described. The experiments were performed on a suspension of isolated mitochondria from the myometrium of rats. Methods of confocal microsc...
Proteomic analysis of temperature-dependent developmental plasticity within the ventricle of juvenile Atlantic salmon (Salmo salar) [0.03%]
温度依赖的早期大西洋鲑鱼心脏发育可塑性的蛋白质组分析
Carlie A Muir,Bradley S Bork,Bryan D Neff et al.
Carlie A Muir et al.
In teleosts, cardiac plasticity plays a central role in mediating thermal acclimation. Previously, we demonstrated that exposure to elevated temperatures throughout development (+4°C) improved acute thermal tolerance of the heart in juveni...
The comparison of endothelial function of moderate intensity interval exercise with continuous exercise in healthy men [0.03%]
中等强度间歇运动与持续运动对健康男性内皮功能影响的比较研究
Burcu Meri C,Serdar Solak,Nurettin Aydogdu et al.
Burcu Meri C et al.
Background/aim: Exercise enhances endothelium-dependent vasodilation; however, it is unclear whether intermittent exercise has a different effect on vascular endothelial function compared to continuous exercise. This stud...
Elucidating the combined effect of intermittent hypoxia training and acetazolamide on hypoxia induced hematological and physiological changes [0.03%]
间断低氧训练和乙酰唑胺对低氧诱导的血液学及生理变化联合影响的研究
Megha A Nimje,Himadri Patir,Rajeshkumar Tirpude et al.
Megha A Nimje et al.
As the number of people travelling to altitude increases, the risk of life threatening medical emergencies also increases. It is important that we have effective strategies to minimize the risk of altitude illness. In this study, an attempt...