Tom A H Janssen,Caroline V Lowisz,Stuart Phillips
Tom A H Janssen
Aging is accompanied by a decline in muscle mass, strength, and physical function, a condition known as sarcopenia. Muscle disuse attributed to decreased physical activity, hospitalization, or illness (e.g. sarcopenia) results in a rapid de...
How PPAR-alpha mediated inflammation may affect the pathophysiology of chronic kidney disease [0.03%]
PPAR-α介导的炎症可能如何影响慢性肾脏疾病的病理生理学
Sepiso K Masenga,Selam Desta,Mark Hatcher et al.
Sepiso K Masenga et al.
Chronic kidney disease (CKD) is a major risk factor for death in adults. Inflammation plays a role in the pathogenesis of CKD, but the mechanisms are poorly understood. Peroxisome proliferator-activated receptor alpha (PPAR-α) is a nuclear...
Yeast supplementation potentiates fluoxetine's anti-depressant effect in mice via modulation of oxido-inflammatory, CREB, and MAPK signaling pathways [0.03%]
酿酒酵母增强氟西汀的抗抑郁作用:通过调节氧化-炎症、CREB和MAPK信号通路实现
Augustina Potokiri,Noah A Omeiza,Abayomi M Ajayi et al.
Augustina Potokiri et al.
Introduction: The therapeutic potential of yeast in the management of depression is unknown. Thus, we evaluated the modulatory effect of nutritional yeast supplementation on antidepressant activity of fluoxetine in mice m...
Glycophagy is involved in cardiac glycogen regulation in response to exercise [0.03%]
运动诱发的心肌糖原调节涉及糖原自噬现象
Samuel L James,Parisa Koutsifeli,Randall F DSouza et al.
Samuel L James et al.
Cardiac glycogen-autophagy ('glycophagy') is disturbed in cardiometabolic pathologies. The physiological role of cardiac glycophagy is unclear. Exercise induces transient cardiac glycogen accumulation. Thus, this study experimentally examin...
Unveiling the ethical void: Bias in reference citations and its academic ramifications [0.03%]
揭开伦理真空:参考文献偏见及其学术影响
Alicia Mattiazzi,Martin Vila-Petroff
Alicia Mattiazzi
Citation bias receives scant attention in discussions of ethics. However, inaccurate citation may lead to significant distortions in scientific understanding. Although ethnical and gender citation disparities have been proposed as critical ...
Effects of aerobic exercise during recovery from eccentric contraction on muscular performance, oxidative stress and inflammation [0.03%]
有氧运动促进离心收缩后肌肉功能、氧化应激及炎症恢复
Luciano A da Silva,Daniel Boeira,Ramiro Doeynart et al.
Luciano A da Silva et al.
This study investigated the effects of aerobic exercise during recovery from eccentric contraction (EC) on muscular performance, oxidative stress, and inflammation. Nineteen male subjects between 18 and 29 years were divided into unexercise...
Effects of cosmos caudatus (Kenikir) antioxidant properties on bone metabolism marker in rat [0.03%]
Cosmos caudatus(Kenikir)抗氧化属性对大鼠骨代谢标志物的影响
Gadis Meinar Sari,Idha Kusumawati,Yoga Akbar Arifandi et al.
Gadis Meinar Sari et al.
Cosmos caudatus leaves are one of around 7500 types of plants that are known to have herbal or medicinal plant properties in Indonesia. This research determines the effectiveness of Cosmos caudatus as an antioxidant agent against cells, bio...
Allosteric modulation of serotonin and dopamine transporters: New insights from computations and experiments [0.03%]
血清素和多巴胺转运体的别构调节:来自计算和实验的新见解
Hoang Nguyen,Mary Hongying Cheng,Ji Young Lee et al.
Hoang Nguyen et al.
Human monoamine transporters (MATs) are critical to regulating monoaminergic neurotransmission by translocating their substrates from the synaptic space back into the presynaptic neurons. As such, their primary substrate binding site S1 has...
Rib cage contributions to inspiratory capacity in patients with cervical spinal cord injury [0.03%]
颈椎脊髓损伤患者吸气量的肋 cage 贡献
Ryo Yoshida,Kenta Kawamura,Yukako Setaka et al.
Ryo Yoshida et al.
Background: Cervical spinal cord injury (CSI) often leads to impaired respiratory function, affecting the overall well-being of patients. This study aimed to investigate the influence of rib cage motion on inspiratory cap...
Olugbenga S Michael,Praghalathan Kanthakumar,Hitesh Soni et al.
Olugbenga S Michael et al.
Chronic kidney disease (CKD) is a progressive and long-term condition marked by a gradual decline in kidney function. CKD is prevalent among those with conditions such as diabetes mellitus, hypertension, and glomerulonephritis. Affecting ov...