Serum electrolytes and blood urea nitrogen changes in end-stage renal disease patients undergoing contemporary haemodialysis: A multi-center cross-sectional study [0.03%]
维持性血液透析终末期肾病患者血清电解质及血尿素氮水平的多中心横断面研究
Wastina Bitewlign,Mohammed Jemal,Enyew Fenta Mengistu et al.
Wastina Bitewlign et al.
Background: Correction of electrolyte imbalance and adequate haemodialysis (HD) minimizes disease complications and hospitalization. Despite the problem, there is a paucity of data regarding the assessment of serum electr...
Exploration of neural mechanisms underlying antidepressant-like property of Ziziphora clinopodioides Lam. essential oil using mouse forced swimming test: Involvement of the monoaminergic systems [0.03%]
使用鼠标强制游泳测试探索Lamessential油的神经机制抗抑郁药理性质：涉及单胺能系统
Saeedeh Ghaffarzadeh Shirabad,Samad Alimohammadi
Saeedeh Ghaffarzadeh Shirabad
Objective: Ziziphora clinopodioides has been valued in Iranian traditional medicine for various medicinal applications. This novel study was conducted to assess the antidepressant-like effect of the essential oil of Zizip...
Differential responses to acute endurance exercise-induced signaling protein phosphorylation and abundance alterations in whole murine gastrocnemius muscle and isolated myofibers [0.03%]
急性耐力运动引起的信号蛋白磷酸化和丰度变化的差异反应：整个小鼠腓肠肌与分离单个肌肉纤维之间的比较研究
Kazuki Uemichi,Takanaga Shirai,Shunsuke Sugiyama et al.
Kazuki Uemichi et al.
Skeletal muscle is composed of diverse cell types, including myofibers. In this study, we investigated how acute endurance exercise could induce signaling protein phosphorylation and abundance alterations using protein lysate extracted from...
Austin Dada,Jing Ren,Yao Shi et al.
Austin Dada et al.
Obesity is a global health epidemic linked to numerous chronic disease conditions and consequences, including type 2 diabetes mellitus (T2DM), cardiovascular disease, chronic kidney disease (CKD) and premature mortality. CKD, which can prog...
The persistence of changes in insulin sensitivity and metabolic gene expression after acute exercise in male and female mice [0.03%]
短暂运动后小鼠胰岛素敏感性及代谢基因表达的持久变化
Jack H Thompson,Alexa M Fooskas,Erica J Locke et al.
Jack H Thompson et al.
Background: Acute exercise has been suggested to increase insulin sensitivity, although the duration of the improvement may last anywhere from 4 to 72 h. In addition, changes in gene expression in response to exercise is ...
Carnosine ameliorates dexamethasone-induced muscle atrophy with associated modulation of ubiquitin ligases and oxidative stress in C57BL/6J female mice [0.03%]
卡那辛改善脱氧皮质醇诱导的小鼠肌肉萎缩及相关的泛素连接酶和氧化应激调节作用（C57BL/6J雌性小鼠模型）
Md Mizanur Rahman,Anayt Ulla,Honomi Ogura et al.
Md Mizanur Rahman et al.
Muscle atrophy, characterized by a decline in muscle mass and function, has limited treatment options, highlighting the need for further research. In this study, we investigated the effect of carnosine, a dipeptide with well-established ant...
The senescent synapse: A look at autophagy, calcium handling, and mitochondrial bioenergetics at the synapse in ageing and Parkinson's disease [0.03%]
衰老的突触：老化和帕金森病中突触自噬、钙离子稳态及线粒体生物能学研究一瞥
Shahzabe Mukhtar,Shikha Kataria,Gloria Cimaglia et al.
Shahzabe Mukhtar et al.
The synapse is a vitally important physiological structure fundamental to electrochemical communication between neurones, and is required for basic and important functions we perform daily. Underpinning the normal physiological function of ...
Mechanisms involved in aminoacidurias: impacts of genetic and environmental factors [0.03%]
氨基酸尿的发病机制：遗传和环境因素的影响
Joseph Abayomi Ajayi,Evelyn Nnashiru Ananias,Muneerah Issa-Lawal et al.
Joseph Abayomi Ajayi et al.
Background: Amino acids play vital roles in protein synthesis, energy metabolism, and cellular function. Aminoacidurias are metabolic disorders characterized by excessive urinary excretion of amino acids resulting from de...
The beneficial effect of propolis during an eight-weeks of resistance training on TNF-α and IL-6 genes expression in the kidney tissue of female Wistar rats undergoing testosterone enanthate consumption [0.03%]
八周阻抗训练联合使用巴西蜂胶和庚酸睾酮对雌性威斯特大鼠肾脏组织中TNF-α和IL-6基因表达的影响研究
Khadijeh Molaei,Sanaz Mirzayan Shanjani,Ali Gorzi et al.
Khadijeh Molaei et al.
This study investigated the potential benefits of propolis in mitigating the adverse effects of testosterone enanthate on the gene expression levels of pro-inflammatory cytokines, tumor necrosis factor-alpha (TNF-α), and interleukin-6 (IL-...
Vascular adaptation in elite female and male rowers across a competitive season [0.03%]
精英男女赛艇运动员在一个竞赛赛季中的血管适应性变化
Sarah R Henley-Martin,Carly J Brade,Hugh Riddell et al.
Sarah R Henley-Martin et al.
The 'athlete's artery' phenotype describes exercise-induced vascular adaptation whereby athletes have enlarged conduit arteries resulting from chronic endurance exercise. However, studies remain limited to males, with few evaluating changes...