Variation in breeding practices and geographic isolation drive subpopulation differentiation, contributing to the loss of genetic diversity within dog breed lineages [0.03%]
繁殖习惯的变化和地理隔离导致亚群分化，从而导致犬品种系内遗传多样性的丧失
Sara Lampi,Jonas Donner,Heidi Anderson et al.
Sara Lampi et al.
Background: Discrete breed ideals are not restricted to delimiting dog breeds from another, but also are key drivers of subpopulation differentiation. As genetic differentiation due to population fragmentation results in ...
Demographic assessment of the Dalmatian dog - effective population size, linkage disequilibrium and inbreeding coefficients [0.03%]
达尔马提亚犬的人口统计评估-有效种群规模，连锁不平衡和近交系数
Danae Vasiliadis,Julia Metzger,Ottmar Distl
Danae Vasiliadis
Background: The calculation of demographic measures is a useful tool for evaluating the genomic architecture of dog breeds and enables ranking dog breeds in terms of genetic diversity. To achieve this for the German Dalma...
Polymorphisms in the CTLA4 promoter sequence are associated with canine hypoadrenocorticism [0.03%]
CTLA4启动子序列中的多态性与犬低肾上腺皮质功能相关
Alisdair M Boag,Andrea Short,Lorna J Kennedy et al.
Alisdair M Boag et al.
Background: Canine hypoadrenocorticism is an immune-mediated endocrinopathy that shares both clinical and pathophysiological similarities with Addison's disease in humans. Several dog breeds are overrepresented in the dis...
Epidemiology and clinical management of elbow joint disease in dogs under primary veterinary care in the UK [0.03%]
英国初级兽医护理下犬肘关节疾病的流行病学和临床管理
Dan G O&#x;Neill,Dave C Brodbelt,Rebecca Hodge et al.
Dan G O&#x;Neill et al.
Background: Conditions affecting the elbow joint are a common cause of lameness in dogs. Primary-care veterinary clinical data are now recognised as a valuable research resource. Using data from the VetCompass Programme, ...