Effects of Aspirin on Kidney Biopsy Bleeding Complications: A Systematic Review and Meta-Analysis (PROSPERO 2021 CRD42021261005) [0.03%]
阿司匹林对肾脏活检出血并发症的影响：系统评价和 meta 分析（Prospero 2021 crd42021261005）
Miguel Relvas,Joana Gonçalves,Inês Castro et al.
Miguel Relvas et al.
Postprocedural bleeding is the main complication of percutaneous kidney biopsy (PKB). Therefore, aspirin is routinely withheld in patients undergoing PKB to reduce the bleeding risk. The authors aimed to examine the association between aspi...
Meta-Analysis
Kidney360. 2023 May 1;4(5):700-710. DOI:10.34067/KID.0000000000000091 2023
Ixazomib for Desensitization (IXADES) in Highly Sensitized Kidney Transplant Candidates: A Phase II Clinical Trial [0.03%]
用于高度敏感的肾脏移植候选者的伊沙佐米脱敏（IXADES）II期临床试验
Nancy Wilson,Shannon Reese,Lucy Ptak et al.
Nancy Wilson et al.
Key Points: Ixazomib treatment resulted in decreases in B-cell subsets and bone marrow lymphocytes.Ixazomib treatment resulted in modest decreases in certain anti-HLA antibody specificities.Ixazomib treatment was tolerat...
Clinical Trial
Kidney360. 2023 Jun 1;4(6):e796-e808. DOI:10.34067/KID.0000000000000113 2023
Mortality Burden and Life-Years Lost Across the Age Spectrum for Adults Living with CKD [0.03%]
成人慢性肾脏病患者全生命周期死亡负担和生命年损失分析
Alexander J Kula,David K Prince,Ronit Katz et al.
Alexander J Kula et al.
Key Points: Limited data exist to inform younger persons with CKD how their risk for mortality compares with equivalently aged individuals without CKD.Compared with the general population without CKD, the age-stratified ...
Single-Bolus Tinzaparin Anticoagulation in Extended Hemodialysis Session: A Feasibility Study [0.03%]
extended hemodialysis会场单次注射依诺肝素抗凝的可行性研究
Benoît Harvey,Jean-Philippe Lafrance,Naoual Elftouh et al.
Benoît Harvey et al.
Key Points: A single bolus of tinzaparin is effective for 8-hour hemodialysis session.Eight-hour simulation sessions with anti-Xa monitoring are useful to adjust tinzaparin dose. ...
Variability of Serum Phosphate in Incident Hemodialysis Patients: Association with All-Cause Mortality [0.03%]
初诊血液透析患者血磷波动与全因死亡率的关系：一项回顾性队列研究
Karlien J Ter Meulen,Xiaoling Ye,Yuedong Wang et al.
Karlien J Ter Meulen et al.
Key Points: An increase in serum phosphate variability is an independent risk factor of mortality.The effects of a positive directional range (DR) is most pronounced in patients with high serum phosphate levels whereas t...
Cardiac Mechanics and Kidney Function Decline in the Cardiovascular Health Study [0.03%]
心血管健康研究中的心脏机械与肾功能下降
Rupal Mehta,Petra Buzkova,Harnish Patel et al.
Rupal Mehta et al.
Key Points: Two-dimensional speckle-tracking echocardiography (2D-STE) can detect early changes in cardiac mechanics and may be able to identify individuals at risk for kidney disease progression.Novel indices of cardiac...
Tissue Inhibitor Metalloproteinase-2 and Insulin-Like Growth Factor Binding Protein-7 Kinetics Following Exposure to High-Dose Methotrexate [0.03%]
大剂量甲氨蝶呤暴露后组织金属基质蛋白酶-2和胰岛素样生长因子结合蛋白-7的动态变化
Jason N Barreto,Erin F Barreto,Kristin C Mara et al.
Jason N Barreto et al.
Urinary TIMP2×IGFBP7 (uTIMP2×IGFBP7) concentrations experienced a rapid and sustained decline after high-dose methotrexate (MTX) exposure.uTIMP2×IGFBP7 kinetics and concentrations after high-dose MTX exposure demonstrated no utility in p...
Prescribing Immunosuppressive Treatment for Older People with Glomerular Diseases: Time to Assess Frailty? [0.03%]
评估免疫抑制治疗老年 glomerular 疾病患者的虚弱状况？
Henry H L Wu,Alexander Woywodt,Andrew C Nixon et al.
Henry H L Wu et al.
Lrpap1 (RAP) Inhibits Proximal Tubule Clathrin Mediated and Clathrin Independent Endocytosis, Ameliorating Renal Aminoglycoside Nephrotoxicity [0.03%]
LRPAP1（Rap）通过抑制近端小管的网格蛋白依赖和非依赖介导的内吞作用，改善肾氨基糖苷类药物毒性
Mark C Wagner,Ruben M Sandoval,Shiv Pratap S Yadav et al.
Mark C Wagner et al.
Key Points: Proximal tubule endocytosis of toxins often leads to nephrotoxicity.Inhibition of endocytosis with receptor-associated protein may serve as a clinical approach to reduce or eliminate kidney damage from a pote...
Paul Rosenstiel,Deepa Luitel,Maria Luna
Paul Rosenstiel
Case Reports
Kidney360. 2023 Feb 1;4(2):287-288. DOI:10.34067/KID.0000000000000034 2023