Apoptosis Inhibitor of Macrophage and Acute Inflammation in IgA Nephropathy [0.03%]
肾小球系膜细胞凋亡抑制蛋白与IgA肾病急性炎症的关系研究
Rina Kato,Hitoshi Suzuki,Ryosuke Aoki et al.
Rina Kato et al.
Background: IgA nephropathy is characterized by mesangial deposits of IgA1-containing immune complex with complement 3 (C3). Our previous study demonstrated that apoptosis inhibitor of macrophage (AIM) plays a critical ro...
The Positive Feedback Regulation of NF-κB/miR-21c/IL-9 Axis in Septic Acute Kidney Injury [0.03%]
NF-κB/miR-21c/IL-9轴的正反馈调节在脓毒症急性肾损伤中的作用
Zheng Li,Juan Wang,Lei Zhang et al.
Zheng Li et al.
Background: Sepsis-associated acute kidney injury (septic AKI) is a leading cause of mortality in critically ill patients. Despite its high prevalence, no specific therapies are currently available, primarily because the ...
Shaping an Early Nephrology Fellowship Curriculum: Results from the American Society of Nephrology Fellow Survey [0.03%]
美国肾脏病学会学员调查:塑造早期肾脏病学培训项目的结果
Ashley M La,Suzanne M Boyle,Kurtis A Pivert et al.
Ashley M La et al.
Background: The transition between residency and nephrology fellowship can be difficult for many trainees because of nephrology's inherent complexity and high-intensity nature as well as the lack of standardization in int...
Association of Loop Diuretic Use with Hospitalization with Atrial Fibrillation in CKD [0.03%]
CKD患者使用袢利尿剂与房颤住院的关系
Katherine Scovner Ravi,Armida LeFranc Torres,Finnian R Mc Causland
Katherine Scovner Ravi
Background: CKD is associated with a high burden of cardiovascular complications, including atrial fibrillation. While loop diuretic medications are commonly prescribed for volume and blood pressure management in CKD, the...
A Pre-Kidney Transplant Blood-Based Next-Generation Sequencing Assay to Predict Early Acute Rejection [0.03%]
一种基于血液的下一代测序检测方法用于预测肾移植前急性排异反应
Beatrice P Concepcion,Oriol Bestard,Milagros Samaniego-Picota et al.
Beatrice P Concepcion et al.
Background: Although donor and recipient characteristics are used to estimate graft failure risk, they remain limited in predicting early acute rejection. We developed and validated a next-generation sequencing (NGS) assa...
Physician Variability in Time to Kidney Biopsy and Glucocorticoid Prescription in IgA Nephropathy: A Population-Based Cohort Study [0.03%]
IgA肾病患者活检和糖皮质激素使用的时间差异及人群队列研究
Bryce Barr,Hailey Hildebrand,Ian W Gibson et al.
Bryce Barr et al.
Background: Practice patterns in the management of IgA nephropathy (IgAN) vary but the extent of physician-level variability in key decisions such as kidney biopsy and glucocorticoid use is unknown. Understanding variabil...
Impact of Disease Recurrence and Outcomes following Kidney Transplantation for Glomerulonephritis: A Prospective Nationwide Cohort Study [0.03%]
免疫介导性肾小球病患者肾移植术后的复发及移植预后:前瞻性全国队列研究
Matthieu Halfon,Patrick Taffé,Christian Bucher et al.
Matthieu Halfon et al.
Background: Patients who receive transplants following kidney failure due to glomerulonephritis (GN-KTx) constitute a significant portion of recipients and may face unique challenges post transplantation, related to the r...
Integrated Study of Vancomycin-Induced Nephrotoxicity in the Context of Sepsis: Animal Models and Transcriptomics [0.03%]
万古霉素致脓毒症鼠肾毒性的整合研究:动物模型和转录组学分析
Yuxi Liu,Linqiong Liu,Hongxu Li et al.
Yuxi Liu et al.
Background: Vancomycin (VAN) is widely used in sepsis but may exacerbate sepsis-associated acute kidney injury (SA-AKI). The mechanisms by which VAN aggravates renal injury in the septic context remain unclear, and early ...
Irregularly Shaped Microplastic Particles Compromise the Integrity of the Glomerular Filtration Barrier of the Kidney [0.03%]
不规则形状的微塑料颗粒损害肾脏肾小球滤过屏障的完整性
Hannah Triebel,Francesco De Luca,Sophia J Baumann et al.
Hannah Triebel et al.
Background: Environmental pollution with microplastics (MPs) is continuously increasing. Humans are inevitably exposed to MPs. Although the shape of MPs influences their biological effects, for practical reasons, most stu...
Correction to: Safety and Efficacy of Tenapanor for Long-term Serum Phosphate Control in Maintenance Dialysis: A 52-Week Randomized Phase 3 Trial (PHREEDOM) [0.03%]
他莫帕诺用于维持性透析患者长期血磷控制的疗效和安全性:一项为期52周随机III期临床研究(PHREEDOM)的纠正说明
Geoffrey A Block,Anthony J Bleyer,Arnold L Silva et al.
Geoffrey A Block et al.