Seeing the Heart through the Eye: Retinal Imaging for Cardiovascular Risk in CKD [0.03%]
透过眼睛看心脏：视网膜影像在慢性肾脏病患者心血管风险评估中的应用
Charumathi Sabanayagam,Cynthia Ciwei Lim
Charumathi Sabanayagam
Can Fyn-Driven Wnt Activation Be the Key to Next-Generation Antifibrotic Therapy in CKD? [0.03%]
Fyn介导的Wnt激活是CKD下一代抗纤维化治疗的关键吗？
Yuanyuan Wang,Dong Zhou
Yuanyuan Wang
IgA-Producing B Cells Exert Regulatory Function Through Granzyme B in Kidney Allograft Tolerance [0.03%]
B细胞通过穿孔素和颗粒酶B发挥调节功能从而诱导肾移植耐受
Laureline Berthelot,Nicolas Degauque,Laura Cappelier et al.
Laureline Berthelot et al.
Background: Tolerant kidney transplant recipients without immunosuppression have a high frequency of circulating granzyme B (GZMB)-expressing regulatory B cells (Breg). Since the precursors of these Bregs remain unknown a...
Effect of Intravenous Iron Dextran on Kidney Outcomes in Acute Kidney Injury with Iron Deficiency: A Randomized Trial [0.03%]
铁缺乏急性肾损伤患者静脉注射铁焦谷氨酸二肽对肾脏结局的影响：一项随机试验
Jonathan S Chávez-Iñiguez,Miguel Ibarra-Estrada,Edgar Joel Carmona-Morales et al.
Jonathan S Chávez-Iñiguez et al.
Background: During AKI, iron deficiency may contribute to worse clinical outcome by interfering cellular repair. Correcting iron deficiency with intravenous (IV) dextran iron may reduce the risk of major adverse kidney ev...
Real-Time ATP Imaging Reveals the Metabolic State During Branching Nephrogenesis [0.03%]
实时ATP成像揭示了分支型肾原基形成的代谢状态
Akiko Mii,Shinya Yamamoto,Masamichi Yamamoto et al.
Akiko Mii et al.
Background: Energy metabolism is fundamental to organ development, yet its role in determining nephron formation remains poorly understood. Disturbances in the intrauterine environment are known to affect nephron endowmen...
Temporal Evolution of the Impact of CKD on COVID-19 Outcomes: A Five-Year Nationwide Analysis [0.03%]
基于全国范围内五年数据分析的慢性肾脏病对新冠肺炎影响的时间演变规律研究
José D González-Barajas,Manuel L Prieto-Magallanes,Carolina Romo-Alvarez et al.
José D González-Barajas et al.
Background: CKD is among the strongest predictors of adverse COVID-19 outcomes, yet how CKD-associated risk evolved across pre-vaccination, roll-out, mass-vaccination, and post-pandemic phases remains incompletely defined...
Bevacizumab Associated Renal Adverse Events Signal Better Prognosis in Ovarian Cancer: A Double-Edged Vascular Endothelial Growth Factor Inhibition [0.03%]
贝伐单抗相关肾不良事件预示卵巢癌有较好的预后：双重刀刃的血管内皮生长因子抑制作用
Cristina Riaza,Marta Álvarez-Nadal,Antonio Casado et al.
Cristina Riaza et al.
Background: Bevacizumab, a monoclonal antibody targeting VEGF-A, is a cornerstone in ovarian cancer. Bevacizumab is associated with renal adverse events, including hypertension, proteinuria, and acute kidney injury. The i...
Impact of Loop Diuretics on Long-Term Kidney Outcome: A Post-Hoc Analysis of the STOP-ACEi Trial [0.03%]
利尿剂对长期肾脏结局的影响：来自STOP-ACEi试验的事后分析
Sunil Bhandari,Samir Mehta,Natalie Ives et al.
Sunil Bhandari et al.
Background: In the STOP-ACEi trial, patients with advanced CKD were randomised to continue or stop renin-angiotensin system inhibitors (RASi) and showed no difference in kidney outcomes. This post-hoc analysis investigate...
Clinical Characteristics and Disease Progression Among Non-Diabetic APOL1-Mediated Kidney Disease Patients and Patients with Other CKD [0.03%]
APOL1介导的肾脏病非糖尿病患者及其它慢性肾病患者的临床特征和疾病进展
Ankit Shah,Manish Maski,Debbie Goldschmidt et al.
Ankit Shah et al.
Background: Apolipoprotein L1 (APOL1)-mediated kidney disease (AMKD) is an aggressive form of chronic kidney disease (CKD). This study described characteristics of non-diabetic patients with AMKD and compared their diseas...